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Research ArticlePediatrics

Intracranial Arterial Tortuosity in Marfan Syndrome and Loeys-Dietz Syndrome: Tortuosity Index Evaluation Is Useful in the Differential Diagnosis

L. Spinardi, G. Vornetti, S. De Martino, R. Golfieri, L. Faccioli, M. Pastore Trossello, C. Graziano, E. Mariucci and A. Donti
American Journal of Neuroradiology October 2020, 41 (10) 1916-1922; DOI: https://doi.org/10.3174/ajnr.A6732
L. Spinardi
aFrom the Neuroradiology Unit (L.S., L.F., M.P.T.)
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G. Vornetti
bRadiology Unit (G.V., S.D.M., R.G.)
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S. De Martino
bRadiology Unit (G.V., S.D.M., R.G.)
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R. Golfieri
bRadiology Unit (G.V., S.D.M., R.G.)
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L. Faccioli
aFrom the Neuroradiology Unit (L.S., L.F., M.P.T.)
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M. Pastore Trossello
aFrom the Neuroradiology Unit (L.S., L.F., M.P.T.)
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C. Graziano
cDepartment of Experimental, Diagnostic and Specialty Medicine, the Department of Medical Genetics (C.G.)
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E. Mariucci
dPediatric Cardiology and GUCH Unit (E.M., A.D.), Sant’Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
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A. Donti
dPediatric Cardiology and GUCH Unit (E.M., A.D.), Sant’Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
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Article Information

vol. 41 no. 10 1916-1922
DOI 
https://doi.org/10.3174/ajnr.A6732
PubMed 
32819908

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received April 5, 2020
  • Accepted after revision June 20, 2020
  • Published online October 6, 2020.

Article Versions

  • Latest version (August 20, 2020 - 08:23).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2020 by American Journal of Neuroradiology

Author Information

  1. L. Spinardia,
  2. G. Vornettib,
  3. S. De Martinob,
  4. R. Golfierib,
  5. L. Facciolia,
  6. M. Pastore Trosselloa,
  7. C. Grazianoc,
  8. E. Mariuccid and
  9. A. Dontid
  1. aFrom the Neuroradiology Unit (L.S., L.F., M.P.T.)
  2. bRadiology Unit (G.V., S.D.M., R.G.)
  3. cDepartment of Experimental, Diagnostic and Specialty Medicine, the Department of Medical Genetics (C.G.)
  4. dPediatric Cardiology and GUCH Unit (E.M., A.D.), Sant’Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
  1. Please address correspondence: Gianfranco Vornetti, MD, Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Policlinico Sant’Orsola-Malpighi, Via Giuseppe Massarenti, 9, 40138 Bologna BO, Italy; e-mail: gianfranco.vornetti{at}gmail.com
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Cite this article
L. Spinardi, G. Vornetti, S. De Martino, R. Golfieri, L. Faccioli, M. Pastore Trossello, C. Graziano, E. Mariucci, A. Donti
Intracranial Arterial Tortuosity in Marfan Syndrome and Loeys-Dietz Syndrome: Tortuosity Index Evaluation Is Useful in the Differential Diagnosis
American Journal of Neuroradiology Oct 2020, 41 (10) 1916-1922; DOI: 10.3174/ajnr.A6732

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Intracranial Arterial Tortuosity in Marfan Syndrome and Loeys-Dietz Syndrome: Tortuosity Index Evaluation Is Useful in the Differential Diagnosis
L. Spinardi, G. Vornetti, S. De Martino, R. Golfieri, L. Faccioli, M. Pastore Trossello, C. Graziano, E. Mariucci, A. Donti
American Journal of Neuroradiology Oct 2020, 41 (10) 1916-1922; DOI: 10.3174/ajnr.A6732
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  • Apoptosis is increased in cortical neurons of female Marfan Syndrome mice
  • Growth Rate Assessed by Vascular Deformation Mapping predicts Type B Aortic Dissection in Marfan Syndrome
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • The Vertebral Artery: A Systematic Review and a Meta-Analysis of the Current Literature
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  • The Role of Genetic Testing in Patients with Heritable Thoracic Aortic Diseases
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    Diagnostics 2023 13 4
  • Prevalence of unruptured intracranial aneurysms in patients with Marfan syndrome: A cross-sectional study and meta-analysis
    Gianfranco Vornetti, Sara Rosa Maria De Martino, Maria Chiara Baroni, Cesare Rossi, Marco Seri, Elisabetta Mariucci, Andrea Donti, Caterina Tonon, Raffaele Lodi, Luca Spinardi
    European Stroke Journal 2023 8 2
  • Effect of Blood Transfusion on Cerebral Hemodynamics and Vascular Topology Described by Computational Fluid Dynamics in Sickle Cell Disease Patients
    Russell P. Sawyer, Sirjana Pun, Kristine A. Karkoska, Cherita A. Clendinen, Michael R. DeBaun, Ephraim Gutmark, Riccardo Barrile, Hyacinth I. Hyacinth
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  • Carotid Dolichoarteriopathy (Elongation) of the Carotid Arteries in Patients with Ischemic Stroke Anamnesis
    Denis A. Golovin, Tatyana M. Rostovtseva, Yuri S. Kudryavtsev, Alexander B. Berdalin, Svetlana E. Lelyuk, Vladimir G. Lelyuk
    Biomedicines 2023 11 10
  • Increased intracranial arterial tortuosity is associated with worse cardiovascular outcome in patients with Loeys-Dietz syndrome
    Gianfranco Vornetti, Luca Spinardi, Elisabetta Mariucci, Claudio Graziano, Maria Chiara Baroni, Luca Faccioli, Andrea Donti
    Journal of Clinical Neuroscience 2022 96
  • Loeys-Dietz syndrome: Case report and review of the literature
    David F. Malyuk, Norbert Campeau, John C. Benson
    Radiology Case Reports 2022 17 3
  • Anatomical analysis of vertebral arteries in vertebrobasilar dolichoectasia: A multi-center study
    Diogo Moniz-Garcia, Jorge Rios Zermeno, Rahul Singh, Gabriel Virador, Loizos Michaelides, Oktay Genel, Omar R. Ortega-Ruiz, Prasanna Vibhute, Vivek Gupta, Sukhwinder Sandhu, William D. Freeman, Rabih G. Tawk
    Clinical Neurology and Neurosurgery 2024 247
  • Arterial tortuosity in pediatric Loeys‐Dietz syndrome patients
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