Article Figures & Data
Figures
- Fig 1.
Flow chart.
- Fig 2.
Example of semiautomatic segmentation of the carotid artery plaque of a 63-year-old subject. Both right (A–C) and left (D–F) carotid arteries are shown, and the red lines in the axial (B and D) and coronal planes (C and F) show the IPH components.
- Fig 3.
Boxplot analysis of the volume of the plaque components (A) and percentages (B) for symptomatic (blue plots) and asymptomatic (red plots) sides.
- Fig 4.
Regression analysis diagrams between total plaque and IPH volume on asymptomatic sides (A and B, respectively) and between total plaque and IPH volume on symptomatic sides (C and D, respectively).
- Fig 5.
ROC curve analysis of the volume of the plaque components (A) and percentages (B) versus the presence of symptoms.
- Fig 6.
Bland-Altman plot analysis for the interobserver agreement in total volume (A) and fatty (B), IPH (C), lipid (D), calcified (E), and mixed (F) tissue.
Tables
Mean or No. (%) Age (yr) 70 ± 11 Male sex 15 (71.4%) Symptomatic side (right) 9 (42.8%) Smoking 11 (52.4%) Hypertension 14 (67%) Hyperlipidemia 13 (61.9%) Diabetes mellitus 8 (38%) History of CHD 9 (42.8%) Family history of CVD 9 (42.8%) Note:—CHD indicates coronary heart disease; CVD, cardiovascular disease.
Ipsilateral Contralateral P Value Total plaque 788 (548–941) 689 (551–1189) .543 Volume (mm3)b IPH 65 (36–161) 15 (12–46) .001 Fatty 154 (80–279) 141 (91–205) .375 Lipid 86 (44–115) 103 (62–157) .095 Mixed 460 (352–555) 424 (313–713) .339 Calcium 118 (66–206) 119 (99–261) .182 Percentage IPH 15% (6%–19%) 3% (2%–5%) .001 Fatty 23% (18%–30%) 18% (14%–21%) .011 Lipid 11% (7%–13%) 15% (10%–16%) .016 Mixed 57% (52%–63%) 61% (56%–65%) .312 Calcium 17% (12%–22%) 18% (15%–26%) .498 IPH/fatty ratio 0.596 (0.344–0.754) 0.171 (0.126–0.1991) .001 AUC SE 95% CI P Value Percentage IPH (<25 HU) 0.889 0.0506 0.754–0.965 .001 Fatty 0.707 0.0832 0.547–0.837 .013 Lipid 0.71 0.0819 0.549–0.839 .01 Mixed 0.595 0.091 0.433–0.744 .295 Calcium 0.551 0.0915 0.390–0.705 .577 Volume IPH (<25 HU) 0.796 0.0695 0.643–0.904 .001 Fatty 0.553 0.091 0.392–0.707 .558 Lipid 0.651 0.0857 0.488–0.791 .077 Mixed 0.529 0.0944 0.370–0.685 .755 Calcium 0.582 0.0907 0.420–0.732 .368 IPH/fatty ratio 0.582 0.0907 0.420–0.732 .368 Note:—AUC indicates area under the curve; SE, standard error.
