Radiogenomics in Medulloblastoma: Can the Human Brain Compete with Artificial Intelligence and Machine Learning?

American Journal of Neuroradiology

Comparison of predictive accuracy defined as AUC on ROC analyses reported in the 2 studies^1,4

Molecular Subgrouping of Medulloblastoma	AUC Using Radiomic MRI Signatures		AUC Using Semantic MRI Features
Molecular Subgrouping of Medulloblastoma	Double 10-Fold Cross-Validation Model	3-Dataset Cross-Validation Model	Training Cohort (n = 76)	Validation Cohort (n = 35)
WNT	0.45	0.45	0.75	0.69
SHH	0.79	0.70	0.94	0.99
Group 3	0.70	0.39	0.73	0.60
Group 4	0.83	0.80	0.85	0.79