Article Figures & Data
Figures
- Fig 1.
MR imaging pattern of ODDD. Mild, diffuse T2 hyperintensity of the supratentorial white matter (B–D) and normal T1 signal (E) characteristic of hypomyelination in patient 1 with involvement of the posterior limb of the internal capsule (B), lateral splenium (C), and typical brain stem tract involvement at the level of the pons (A). Note T2 hypointensity of the Rolandic cortex compared with subcortical NAWM (arrows) of the medial and superior frontal gyri (B–D) and of the primary visual cortex compared with the anterior limb of the internal capsule, genu, and subcortical frontal NAWM (B and C). The craniocervical junction is normal (F). For an overview of MR imaging changes of all patients see On-line Fig 1.
- Fig 2.
Pattern of brain stem tract involvement. T2WI at the level of the pons demonstrates characteristic involvement of the pyramidal tract (1), lemniscus medialis (2, black arrow), raphe pontis (3, black arrow), middle cerebellar peduncle (4), and the triangular lateral pontine T2 hyperintensity consistent with the anterior course of the pontocerebellar fibers forming the middle cerebellar peduncle (5); schematic representation of tracts is given in inset in A 2, 3 in black. A, Patient 1, B, patient 2, C, patient 3, D, patient 4, E, patient 5, F, patient 6. Field strength is 3T in patient 3; otherwise, it is 1.5T. Images are from the last scan from patients with multiple scans.
