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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticlePediatric Neuroimaging

“Ears of the Lynx” MRI Sign Is Associated with SPG11 and SPG15 Hereditary Spastic Paraplegia

B. Pascual, S.T. de Bot, M.R. Daniels, M.C. França, C. Toro, M. Riverol, P. Hedera, M.T. Bassi, N. Bresolin, B.P. van de Warrenburg, B. Kremer, J. Nicolai, P. Charles, J. Xu, S. Singh, N.J. Patronas, S.H. Fung, M.D. Gregory and J.C. Masdeu
American Journal of Neuroradiology January 2019, 40 (1) 199-203; DOI: https://doi.org/10.3174/ajnr.A5935
B. Pascual
aFrom the Departments of Neurology (B.P., M.R.D., J.C.M.)
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S.T. de Bot
dDepartment of Neurology (S.T.d.B.), Leiden University Medical Centre, Leiden, the Netherlands
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M.R. Daniels
aFrom the Departments of Neurology (B.P., M.R.D., J.C.M.)
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M.C. França Jr
eDepartment of Neurology (M.C.F.), University of Campinas, Campinas, Brazil
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C. Toro
fNational Institutes of Health Intramural Research Program (C.T., N.J.P., M.D.G.), Bethesda, Maryland
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M. Riverol
gDepartment of Neurology (M.R.), Clínica Universidad de Navarra, Pamplona, Spain
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P. Hedera
hDepartment of Neurology (P.H.), Vanderbilt University Medical Center, Nashville, Tennessee
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M.T. Bassi
iLaboratory of Molecular Biology (M.T.B.), Scientific Institute Istituto di Ricovero e Cura a Carattere Scientifico E. Medea, Bosisio Parini, Lecco, Italy
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N. Bresolin
jDepartment of Neuroscience and Mental Health (N.B.), University Hospital Policlinico Ca'Granda, University of Milan, Milan, Italy
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B.P. van de Warrenburg
kDepartment of Neurology (B.P.v.d.W.), Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands
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B. Kremer
lDepartment of Neurology (B.K.), University Medical Center Groningen, Groningen, the Netherlands
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J. Nicolai
mDepartment of Neurology (J.N.), Maastricht University Medical Centre, Maastricht, the Netherlands
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P. Charles
nDepartment of Genetics (P.C.), Hôpital Pitié-Salpêtrière, Paris, France.
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J. Xu
bBiostatistics (J.X.)
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S. Singh
cRadiology (S.S., S.H.F.), Houston Methodist Research Institute, Houston, Texas
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N.J. Patronas
fNational Institutes of Health Intramural Research Program (C.T., N.J.P., M.D.G.), Bethesda, Maryland
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S.H. Fung
cRadiology (S.S., S.H.F.), Houston Methodist Research Institute, Houston, Texas
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M.D. Gregory
fNational Institutes of Health Intramural Research Program (C.T., N.J.P., M.D.G.), Bethesda, Maryland
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J.C. Masdeu
aFrom the Departments of Neurology (B.P., M.R.D., J.C.M.)
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References

  1. 1.↵
    1. Chrestian N,
    2. Dupré N,
    3. Gan-Or Z, et al
    . Clinical and genetic study of hereditary spastic paraplegia in Canada. Neurol Genet 2017;3:e122 doi:10.1212/NXG.0000000000000122 pmid:27957547
    Abstract/FREE Full Text
  2. 2.↵
    1. Goizet C,
    2. Boukhris A,
    3. Maltete D, et al
    . SPG15 is the second most common cause of hereditary spastic paraplegia with thin corpus callosum. Neurology 2009;73:1111–19 doi:10.1212/WNL.0b013e3181bacf59 pmid:19805727
    Abstract/FREE Full Text
  3. 3.↵
    1. Hehr U,
    2. Bauer P,
    3. Winner B, et al
    . Long-term course and mutational spectrum of spatacsin-linked spastic paraplegia. Ann Neurol 2007;62:656–65 doi:10.1002/ana.21310 pmid:18067136
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Kara E,
    2. Tucci A,
    3. Manzoni C, et al
    . Genetic and phenotypic characterization of complex hereditary spastic paraplegia. Brain 2016;139:1904–18 doi:10.1093/brain/aww111 pmid:27217339
    CrossRefPubMed
  5. 5.↵
    1. Pensato V,
    2. Castellotti B,
    3. Gellera C, et al
    . Overlapping phenotypes in complex spastic paraplegias SPG11, SPG15, SPG35 and SPG48. Brain 2014;137:1907–20 doi:10.1093/brain/awu121 pmid:24833714
    CrossRefPubMed
  6. 6.↵
    1. Stevanin G,
    2. Azzedine H,
    3. Denora P, et al
    ; SPATAX consortium. Mutations in SPG11 are frequent in autosomal recessive spastic paraplegia with thin corpus callosum, cognitive decline and lower motor neuron degeneration. Brain 2008;131:772–84 doi:10.1093/brain/awm293 pmid:18079167
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Estrada-Cuzcano A,
    2. Martin S,
    3. Chamova T, et al
    . Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78). Brain 2017;140:287–305 doi:10.1093/brain/aww307 pmid:28137957
    CrossRefPubMed
  8. 8.↵
    1. Eichler F,
    2. Ratai E,
    3. Carroll JJ, et al
    . Inherited or acquired metabolic disorders. Handb Clin Neurol 2016;135:603–36 doi:10.1016/B978-0-444-53485-9.00029- pmid:27432685
    CrossRefPubMed
  9. 9.↵
    1. Abdel-Hamid MS,
    2. Issa MY,
    3. Otaify GA, et al
    . PGAP3-related hyperphosphatasia with mental retardation syndrome: report of 10 new patients and a homozygous founder mutation. Clin Genet 2018;93:84–91 doi:10.1111/cge.13033 pmid:28390064
    CrossRefPubMed
  10. 10.↵
    1. Barmherzig R,
    2. Bullivant G,
    3. Cordeiro D, et al
    . A new patient with intermediate severe Salla disease with hypomyelination: a literature review for Salla disease. Pediatr Neurol 2017;74:87–91.e82 doi:10.1016/j.pediatrneurol.2017.05.022 pmid:28662915
    CrossRefPubMed
  11. 11.↵
    1. Depienne C,
    2. Nava C,
    3. Keren B, et al
    . Genetic and phenotypic dissection of 1q43q44 microdeletion syndrome and neurodevelopmental phenotypes associated with mutations in ZBTB18 and HNRNPU. Hum Genet 2017;136:463–79 doi:10.1007/s00439-017-1772-0 pmid:28283832
    CrossRefPubMed
  12. 12.↵
    1. Flex E,
    2. Niceta M,
    3. Cecchetti S, et al
    . Biallelic mutations in TBCD, encoding the tubulin folding cofactor D, perturb microtubule dynamics and cause early-onset encephalopathy. Am J Hum Genet 2016;99:962–73 doi:10.1016/j.ajhg.2016.08.003 pmid:27666370
    CrossRefPubMed
  13. 13.↵
    1. Kurata H,
    2. Terashima H,
    3. Nakashima M, et al
    . Characterization of SPATA5-related encephalopathy in early childhood. Clin Genet 2016;90:437–44 doi:10.1111/cge.12813 pmid:27246907
    CrossRefPubMed
  14. 14.↵
    1. Lamers IJC,
    2. Reijnders MR,
    3. Venselaar H, et al
    . Recurrent de novo mutations disturbing the GTP/GDP binding pocket of RAB11B cause intellectual disability and a distinctive brain phenotype. Am J Hum Genet 2017;101:824–32 doi:10.1016/j.ajhg.2017.09.015 pmid:29106825
    CrossRefPubMed
  15. 15.↵
    1. Meng L,
    2. Donti T,
    3. Xia F, et al
    . Homozygous variants in pyrroline-5-carboxylate reductase 2 (PYCR2) in patients with progressive microcephaly and hypomyelinating leukodystrophy. Am J Med Genet A 2017;173:460–70 doi:10.1002/ajmg.a.38049 pmid:27860360
    CrossRefPubMed
  16. 16.↵
    1. Rosti RO,
    2. Dikoglu E,
    3. Zaki MS, et al
    . Extending the mutation spectrum for Galloway-Mowat syndrome to include homozygous missense mutations in the WDR73 gene. Am J Med Genet A 2016;170A:992–98 doi:10.1002/ajmg.a.37533 pmid:27001912
    CrossRefPubMed
  17. 17.↵
    1. Sidhu M,
    2. Brady L,
    3. Tarnopolsky M, et al
    . Clinical manifestations associated with the N-Terminal-Acetyltransferase NAA10 gene mutation in a girl: Ogden syndrome. Pediatr Neurol 2017;76:82–85 doi:10.1016/j.pediatrneurol.2017.07.010 pmid:28967461
    CrossRefPubMed
  18. 18.↵
    1. Kraus MF,
    2. Susmaras T,
    3. Caughlin BP, et al
    . White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study. Brain 2007;130:2508–19 doi:10.1093/brain/awm216 pmid:17872928
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Mori S,
    2. Wakana S,
    3. van Zijl PC, et al
    . MRI Atlas of Human White Matter. Amsterdam: Elsevier; 2005, see: https://www.elsevier.com/books/mri-atlas-of-human-white-matter/mori/978-0-444-51741-8
  20. 20.↵
    1. Riverol M,
    2. Samaranch L,
    3. Pascual B, et al
    . Forceps minor region signal abnormality “ears of the lynx”: an early MRI finding in spastic paraparesis with thin corpus callosum and mutations in the spatacsin gene (SPG11) on chromosome 15. J Neuroimaging 2009;19:52–60 doi:10.1111/j.1552-6569.2008.00327.x pmid:19040626
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. Sze G,
    2. De Armond SJ,
    3. Brant-Zawadzki M, et al
    . Foci of MRI signal (pseudo lesions) anterior to the frontal horns: histologic correlations of a normal finding. AJR Am J Roentgenol 1986;147:331–37 doi:10.2214/ajr.147.2.331 pmid:3487952
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. de Bot ST,
    2. Burggraaff RC,
    3. Herkert JC, et al
    . Rapidly deteriorating course in Dutch hereditary spastic paraplegia type 11 patients. Eur J Hum Genet 2013;21:1312–15 doi:10.1038/ejhg.2013.27 pmid:23443022
    CrossRefPubMed
  23. 23.↵
    1. França MC Jr.,
    2. D'Abreu A,
    3. Maurer-Morelli CV, et al
    . Prospective neuroimaging study in hereditary spastic paraplegia with thin corpus callosum. Mov Disord 2007;22:1556–62 doi:10.1002/mds.21480 pmid:17516453
    CrossRefPubMedWeb of Science
  24. 24.↵
    1. Hertzog MA
    . Considerations in determining sample size for pilot studies. Res Nurs Health 2008;31:180–91 doi:10.1002/nur.20247 pmid:18183564
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Landis JR,
    2. Koch GG
    . The measurement of observer agreement for categorical data. Biometrics 1977;33:159–74 doi:10.2307/2529310 pmid:843571
    CrossRefPubMedWeb of Science
  26. 26.↵
    1. Stevanin G,
    2. Santorelli FM,
    3. Azzedine H, et al
    . Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum. Nat Genet 2007;39:366–72 doi:10.1038/ng1980 pmid:17322883
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Faber I,
    2. Servelhere KR,
    3. Martinez ARM, et al
    . Clinical features and management of hereditary spastic paraplegia. Arq Neuropsiquiatr 2014;72:219–26 doi:10.1590/0004-282X20130248 pmid:24676440
    CrossRefPubMed
  28. 28.↵
    1. Renvoisé B,
    2. Chang J,
    3. Singh R, et al
    . Lysosomal abnormalities in hereditary spastic paraplegia types SPG15 and SPG11. Ann Clin Transl Neurol 2014;1:379–89 doi:10.1002/acn3.64 pmid:24999486
    CrossRefPubMed
  29. 29.↵
    1. Giannoccaro MP,
    2. Liguori R,
    3. Arnoldi A, et al
    . Atypical late-onset hereditary spastic paraplegia with thin corpus callosum due to novel compound heterozygous mutations in the SPG11 gene. J Neurol 2014;261:1825–27 doi:10.1007/s00415-014-7443-3 pmid:25059394
    CrossRefPubMed
  30. 30.↵
    1. Fraidakis MJ,
    2. Brunetti M,
    3. Blackstone C, et al
    . Novel compound heterozygous spatacsin mutations in a Greek kindred with hereditary spastic paraplegia SPG11 and dementia. Neurodegener Dis 2016;16:373–81 doi:10.1159/000444715 pmid:27318863
    CrossRefPubMed
  31. 31.↵
    1. Chakrabarty S,
    2. Vijayakumar N,
    3. Radhakrishnan K, et al
    . Spastizin mutation in hereditary spastic paraplegia with thin corpus callosum. J Neurol 2016;263:2130–32 doi:10.1007/s00415-016-8258-1 pmid:27544497
    CrossRefPubMed
  32. 32.↵
    1. Pacheco FT,
    2. Rego MM,
    3. do Rego JI, et al
    . “Ears of the lynx” sign in a Marchiafava-Bignami patient: structural basis and fiber-tracking DTI contribution to the understanding of this imaging abnormality. J Neuroimaging 2014;24:205–07 doi:10.1111/j.1552-6569.2012.00714.x pmid:23216703
    CrossRefPubMed
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B. Pascual, S.T. de Bot, M.R. Daniels, M.C. França, C. Toro, M. Riverol, P. Hedera, M.T. Bassi, N. Bresolin, B.P. van de Warrenburg, B. Kremer, J. Nicolai, P. Charles, J. Xu, S. Singh, N.J. Patronas, S.H. Fung, M.D. Gregory, J.C. Masdeu
“Ears of the Lynx” MRI Sign Is Associated with SPG11 and SPG15 Hereditary Spastic Paraplegia
American Journal of Neuroradiology Jan 2019, 40 (1) 199-203; DOI: 10.3174/ajnr.A5935

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“Ears of the Lynx” MRI Sign Is Associated with SPG11 and SPG15 Hereditary Spastic Paraplegia
B. Pascual, S.T. de Bot, M.R. Daniels, M.C. França, C. Toro, M. Riverol, P. Hedera, M.T. Bassi, N. Bresolin, B.P. van de Warrenburg, B. Kremer, J. Nicolai, P. Charles, J. Xu, S. Singh, N.J. Patronas, S.H. Fung, M.D. Gregory, J.C. Masdeu
American Journal of Neuroradiology Jan 2019, 40 (1) 199-203; DOI: 10.3174/ajnr.A5935
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  • 'Ear of the lynx sign: hereditary spastic paraplegia (HSP) type 11
  • Clinical and neurogenetic characterisation of autosomal recessive RBL2-associated progressive neurodevelopmental disorder
  • Systematic Analysis of Brain MRI Findings in Adaptor Protein Complex 4-Associated Hereditary Spastic Paraplegia
  • 'Ears of the Lynx sign: an important and useful MRI clue for diagnosis of hereditary spastic paraplegia (HSP) caused by mutation in SPG 15 gene
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