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Treatment-related outcomes after Y-stent-assisted coiling of bifurcation aneurysms
Variables Results of Systematic Review and Meta-Analysis No. of Articles Statistic (95% CI) (I2) Angiographic outcomes Rate of successful stent deployment 550/569 = 97% 20 (96–99) (I2 = 0%) Immediate aneurysm occlusion rate (RR 1–2) 352/468 = 82.2% 15 (71.4–93) (I2 = 92%) Long-term aneurysm occlusion rate (RR 1–2) 564/598 = 95.4% 24 (93.7–97) (I2 = 0%) Aneurysm recanalization 20/496 = 3% 19 (1.5–4.5) (I2 = 0%) Recanalization among anterior circulation 2/89 = 2% 9 (0.9–9) (I2 = 0%) Recanalization among posterior circulation 11/130 = 4% 12 (2–9) (I2 = 0%) Mean size of recanalized vs nonrecanalized aneurysms (mm) 11 ± 2.4 vs 7 ± 1.18 7 Rate of retreatment of recanalized aneurysms 10/20 = 50% 19 (29–70) Treatment-related complications and clinical outcomes Overall treatment-related complications 63/614 = 8.9% 23 (5.8–12.1) (I2 = 44%) Periprocedural/early complications (within 30 days) 46/574 = 6.7% 21 (4–9) (I2 = 35%) Delayed complications (after 30 days) 9/574 = 2.1% 21 (1–3) (I2 = 0%) Transient complications 33/540 = 6.5% 20 (2.2–6) (I2 = 21%) Symptomatic complications without permanent deficits 22/540 = 3% 20 (1.3–4) (I2 = 35%) Permanent complications 18/540 = 2.4% 20 (1.2–3.7) (I2 = 0%) Treatment-related mortality 5/668 = 1.1% 23 (0.3–1.9) (I2 = 0%) Overall rate of good neurologic outcome 291/317 = 94.5% 15 (92–97) (I2 = 7%) Type of complications Thromboembolic complications 44/594 = 6.5% 22 (3–7.6) (I2 = 29%) Hemorrhagic complications 11/594 = 2% 22 (0.7–3) (I2 = 0%) Acute in-stent thrombosis 20/577 = 2.1% 22 (1.6–6) (I2 = 0%) Aneurysm rupture after treatment 0/650 = 0% 22 Chronic in-stent stenosis 10/295 = 2.3% 11 (0.6–4) (I2 = 0%) Note:—RR indicates Raymond-Roy grade.