Index by author

The authors automated the identification of enlarged perivascular spaces in brain MR images using a custom quantitative program designed with Matlab. They quantified the densities of enlarged perivascular spaces for patients with mild cognitive impairment (n=14) and age-matched cognitively healthy controls (n=15) and compared them to determine whether the density of enlarged perivascular spaces can serve as an imaging surrogate for mild cognitive impairment diagnosis. The density of enlarged perivascular spaces was found to be significantly higher in those with mild cognitive impairment compared with age-matched healthy control subjects.