Article Figures & Data
Figures
- Fig 1.
Task-based fMRI map demonstrating activation of the VSMN with the vertical tongue movement task in a single subject (A). Rs-fMRI maps with the best visual correlates to tb-fMRI at different ICA groups (B–E) were selected.
- Fig 2.
Rs-fMRI ICA maps (yellow) and Tb-fMRI T-maps (red) were thresholded, and 100 threshold maps were generated for each in a single subject. At a low threshold, there is artificially higher overlap (orange) between the maps due to noise. At a very high threshold, the overlap is smaller.
- Fig 3.
The Dice coefficient matrix at different thresholds at the subject level between the rs-fMRI (x-axis) at ICA 20 and tb-fMRI (y-axis). An artificially high Dice coefficient is seen in the top left corner of the left map due to overlap of noise. A noise matrix was generated (middle map) and was subtracted (right map). Noise-removed Dice coefficient maps were generated for all the subjects across 4 different ICA orders.
- Fig 4.
fMRI comparison among the patients. The number of patients with full, partial, and no match between tb- and rs-fMRI at different ICA levels is demonstrated.
- Fig 5.
Group mean Dice coefficient maps across all the subjects at each ICA order calculated from subject-level noise-removed Dice coefficient maps. The x-axis depicts the rs-fMRI threshold levels, and the y-axis depicts the tb-fMRI threshold levels with the color bar demonstrating the Dice coefficient value.
- Fig 6.
Violin plots of Dice VUS across ICA orders. The mean Dice VUS for each ICA order is denoted by white diamonds. As the ICA order increases, there are larger numbers of subjects with higher Dice VUS values as reflected in the greater width of the violin plots corresponding to kernel densities.
- Fig 7.
Sample subject (patient 23 in the On-line Table) demonstrating an expansile mass lesion centered in the postcentral gyrus (arrows). Signal abnormality is extended to the subcortical white matter of the precentral gyrus. Red denotes tongue motor task activation, green denotes the VSMN network identified from rs-fMRI (ICA 50), and yellow denotes areas of overlap between tb- and rs-fMRI.
Tables
- Table 1:
Probability of getting a full match between rs-fMRI and tb-fMRI maps as a function of number of ICA components
ICA 20 ICA 30 ICA 40 ICA 50 Probability 0.53 0.65 0.69 0.73 - Table 2:
Dice coefficient values range, median, and mean at the subject level across different ICA orders
Minimum Maximum Median Mean ICA 20 −0.214 0.528 0.009 0.062 ICA 30 −0.134 0.540 0.015 0.071 ICA 40 −0.056 0.587 0.024 0.085 ICA 50 −0.368 0.616 0.024 0.086
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