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Research ArticleNeurointervention

Clinical Impact of Flat Panel Volume CT Angiography in Evaluating the Accurate Intraoperative Deployment of Flow-Diverter Stents

F. Clarençon, F. Di Maria, J. Gabrieli, E. Shotar, V. Degos, A. Nouet, A. Biondi and N.-A. Sourour
American Journal of Neuroradiology October 2017, 38 (10) 1966-1972; DOI: https://doi.org/10.3174/ajnr.A5343
F. Clarençon
aFrom the Departments of Interventional Neuroradiology (F.C., J.G., E.S., N.-A.S.)
dParis VI University (F.C., J.G., E.S., V.D.), Pierre et Marie Curie, Paris. France
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F. Di Maria
eDepartment of Interventional Neuroradiology (F.D.M.), Foch Hospital, Suresnes, France
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J. Gabrieli
aFrom the Departments of Interventional Neuroradiology (F.C., J.G., E.S., N.-A.S.)
dParis VI University (F.C., J.G., E.S., V.D.), Pierre et Marie Curie, Paris. France
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E. Shotar
aFrom the Departments of Interventional Neuroradiology (F.C., J.G., E.S., N.-A.S.)
dParis VI University (F.C., J.G., E.S., V.D.), Pierre et Marie Curie, Paris. France
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V. Degos
bAnesthesiology (V.D.)
dParis VI University (F.C., J.G., E.S., V.D.), Pierre et Marie Curie, Paris. France
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A. Nouet
cNeurosurgery (A.N.), Pitié-Salpêtrière Hospital. Paris France
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A. Biondi
fDepartment of Neuroradiology and Endovascular Therapy (A.B.), Besançon University Hospital, Besançon, France.
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N.-A. Sourour
aFrom the Departments of Interventional Neuroradiology (F.C., J.G., E.S., N.-A.S.)
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    Fig 1.

    A 51-year-old woman presenting a recurrence of a left unruptured PComA aneurysm previously clipped. A, DSA in working projection showing the 5.2 × 5.0 mm recurrence with a 4.7 mm neck (arrowheads). B, Unsubtracted snapshot of the DSA in working projection displaying the clip (white arrow). C, Unsubtracted snapshot during the deployment of the FDS (Pipeline Embolization Device) from the left M1 segment to the carotid siphon. D and E, Snapshots from the FPV-CTA acquisition performed with 20% contrast media intra-arterial injection through the guiding catheter; MIP reconstruction. Satisfactory deployment of the stent is seen. Note the presence of the clip from the previous treatment (black arrows) and the microcatheter's tip, left in the FDS lumen during the acquisition (white arrows). Note that neither the clip nor the microcatheter's tip hamper the FDS visualization. F and G, Final DSA in working projection after FDS deployment (F, early phase; G, late phase). Stagnation of the contrast media within the aneurysm sac is seen at late phase (G). PComA indicates posterior communicating artery.

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    Fig 2.

    A 40-year-old woman treated for an incidental large right carotid ophthalmic aneurysm. A, Right ICA DSA in working projection showing the large paraclinoid aneurysm. B, Plain x-ray snapshot in working projection after the deployment of the FDS (Pipeline Embolization Device) in the parent artery, with a microcatheter jailed in the aneurysm sac (arrow). C, FPV-CTA acquisition, MIP reconstruction in sagittal view showing the satisfactory deployment of the FDS with the microcatheter jailed between the FDS and the wall of the parent artery (arrows). D, FPV-CTA, axial view. The jailed microcatheter is seen between the FDS and the wall of the parent artery (arrow). E, Final control DSA in working projection after loose coiling of the sac. Satisfactory exclusion of the sac is seen.

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    Fig 3.

    A 52-year-old woman treated for an unruptured left carotid ophthalmic large-neck aneurysm. A, Left ICA DSA in working projection (A) and 3D rotational angiography (B) showing the bi-lobed paraclinoid aneurysm with a large neck. Two overlapped FDSs (NeuroEndoGraft) were deployed in the carotid siphon to cover the aneurysm neck. C, Unsubtracted plain x-ray in lateral projection; the satisfactory opening of the distal FDS is demonstrated, but the proximal aspect of the proximal FDS is not clearly seen. D, FPV-CTA (sagittal view MIP reconstruction clearly separates the 2 FDSs and confirms an incomplete opening of the proximal aspect of the proximal FDS (arrow), which was subsequently treated by intrastent balloon angioplasty (E). F and G, Plain x-ray snapshots (F, without and G, with contrast media injection) in lateral projection showing a satisfactory opening of the FDS. H, One-year follow-up DSA in working projection showing the complete occlusion of the aneurysm.

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    Fig 4.

    A 30-year-old man treated for a traumatic left carotid cavernous fistula, 1 month after a severe traumatic brain injury. A, Left ICA DSA in lateral projection before stent placement. Note the filling of the ipsilateral cavernous sinus (arrows). Treatment with an FDS covering the ICA's arterial tear was chosen. One FDS (NeuroEndoGraft) was deployed in the carotid siphon to cover the arterial tear. B, Unsubtracted snapshot after the stent deployment. No obvious malapposition of the stent is seen. C and D, FPV-CTA after the stent deployment in sagittal MIP reconstruction (C) and thin section sagittal oblique reconstruction (D). This acquisition clearly shows a narrowing of the distal aspect of the FDS (arrow) that prompted the operator to perform an intrastent balloon angioplasty. E and F, Postangioplasty FPV-CTA (E, sagittal view, MIP reconstruction; F, thin-section sagittal oblique reconstruction) shows incomplete but satisfactory opening of the distal aspect of the FDS (arrow). G, One-year follow-up DSA showing the complete cure of the traumatic fistula.

Tables

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    Table 1:

    Patient demographics and aneurysm characteristics

    Demographics/CharacteristicsOverall PopulationPatients Who Underwent FPV-CTA
    No. of patients8368
    Age (mean ± SD)51 ± 1251 ± 12
    Female (no., %)62 (75)51 (75)
    No. of aneurysms8770
    Direct CC fistula (no.)11
    No. of procedures8470
    Aneurysm locations
        Anterior circulation (no., %)76 (87.4)63 (90)
            Paraclinoid ICA (no., %)36 (41.4)28 (40)
            Cavernous ICA (no., %)20 (23)17 (24)
            ACA/AComA (no., %)7 (8)6 (8.6)
            ICA terminus (no., %)4 (4.6)4 (5.7)
            AChoA/PComA (no., %)4 (4.6)4 (5.7)
            MCA (no., %)4 (4.6)3 (4.3)
            Petrous ICA (no., %)1 (1.1)1 (1.4)
        Posterior circulation11 (12.6)7 (10)
            Vertebral artery (no., %)5 (5.7)3 (4.3)
            BA (no., %)3 (3.4)1 (1.4)
            PCA (no., %)2 (2.3)2 (2.9)
            SCA (no., %)1 (1.1)1 (1.45)
    Aneurysm maximum diameter (mean ± SD)9.2 ± 6.59.8 ± 6.5
    Aneurysm neck (mean ± SD)5.4 ± 35.4 ± 3
    Acutely ruptured aneurysms (no., %)5 (5.7)3 (4.3)
    Recanalized aneurysms (no., %)16 (18.4)13 (18.6)
            Previously clipped (no., %)2 (2.3)2 (2.9)
            Previously coiled (no., %)14 (16.1)11 (15.7)
    • Note:—ACA indicates anterior cerebral artery; AChoA, anterior choroidal artery; AComA, anterior communicating artery; BA, basilar artery; CC, carotid cavernous; PCA, posterior cerebral artery; PComA, posterior communicating artery; SCA, superior cerebellar artery.

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    Table 2:

    Interrater agreements and analysis in consensus for the evaluation of FPV-CTAs

    Interrater agreements
        Stent visualization qualityκ = 0.38
        Stent rate visualizedκ = 0.49
        Misdeploymentκ = 0.57
    Analysis in consensus
        Good visualization83.8%
        Fair/poor visualization16.2%
        Complete visualization73.5%
        Partial visualization27%
        Satisfactory opening88.2%
        Misdeployment11.8%
    • View popup
    Table 3:

    Univariate and multivariate analyses

    VariablesPoor/Fair FDS VisualizationGood FDS VisualizationUnivariate Analysis (P Value)Multivariate Analysis (P Value)
    Age, yr (mean ± SD)51.5 ± 12.751.5 ± 12.3.12.7
    Female (no., %)7 (64)44 (77).45.61
    Anterior location (no., %)10 (90)51 (89)1.94
    Acute rupture (no., %)0 (0)3 (5)1.64
    Recanalization/recurrence4 (36)7 (12).73.34
    Aneurysm max. diameter, mm (mean ± SD)15.5 ± 8.28.7 ± 5.2<.001a.06
    Aneurysm neck, mm (mean ± SD)6.35 ± 3.655.1 ± 2.2.13.795
    Stent type (PED; no., %)36 (63)8 (73).73.96
    No. of stents (mean ± SD)1.2 ± 0.51.1 ± 0.3.25.92
    Additional coils (no., %)8 (73)14 (25).004a.015a
    Microcatheter in place (no., %)2 (18)11 (19)1.28
    Contrast media stagnation (no., %)2 (18)2 (3.5).12.02a
    • Note:—max indicates maximum; PED, Pipeline Embolization Device.

    • ↵a Statistically significant difference.

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American Journal of Neuroradiology: 38 (10)
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F. Clarençon, F. Di Maria, J. Gabrieli, E. Shotar, V. Degos, A. Nouet, A. Biondi, N.-A. Sourour
Clinical Impact of Flat Panel Volume CT Angiography in Evaluating the Accurate Intraoperative Deployment of Flow-Diverter Stents
American Journal of Neuroradiology Oct 2017, 38 (10) 1966-1972; DOI: 10.3174/ajnr.A5343

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Clinical Impact of Flat Panel Volume CT Angiography in Evaluating the Accurate Intraoperative Deployment of Flow-Diverter Stents
F. Clarençon, F. Di Maria, J. Gabrieli, E. Shotar, V. Degos, A. Nouet, A. Biondi, N.-A. Sourour
American Journal of Neuroradiology Oct 2017, 38 (10) 1966-1972; DOI: 10.3174/ajnr.A5343
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