Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • Advancing NeuroMRI with High-Relaxivity Contrast Agents
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • Advancing NeuroMRI with High-Relaxivity Contrast Agents
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates


Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleAdult Brain
Open Access

Characteristics of Diffusional Kurtosis in Chronic Ischemia of Adult Moyamoya Disease: Comparing Diffusional Kurtosis and Diffusion Tensor Imaging

K. Kazumata, K.K. Tha, H. Narita, Y.M. Ito, H. Shichinohe, M. Ito, H. Uchino and T. Abumiya
American Journal of Neuroradiology August 2016, 37 (8) 1432-1439; DOI: https://doi.org/10.3174/ajnr.A4728
K. Kazumata
aFrom the Departments of Neurosurgery (K.K., H.S., M.I., H.U., T.A.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for K. Kazumata
K.K. Tha
bRadiobiology and Medical Engineering (K.K.T.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for K.K. Tha
H. Narita
cPsychiatry (H.N.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for H. Narita
Y.M. Ito
dBiostatistics (Y.M.I.), Hokkaido University Graduate School of Medicine, Sapporo, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Y.M. Ito
H. Shichinohe
aFrom the Departments of Neurosurgery (K.K., H.S., M.I., H.U., T.A.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for H. Shichinohe
M. Ito
aFrom the Departments of Neurosurgery (K.K., H.S., M.I., H.U., T.A.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M. Ito
H. Uchino
aFrom the Departments of Neurosurgery (K.K., H.S., M.I., H.U., T.A.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for H. Uchino
T. Abumiya
aFrom the Departments of Neurosurgery (K.K., H.S., M.I., H.U., T.A.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for T. Abumiya
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Kuroda S,
    2. Houkin K
    . Moyamoya disease: current concepts and future perspectives. Lancet Neurol 2008;7:1056–66 doi:10.1016/S1474-4422(08)70240-0 pmid:18940695
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Karzmark P,
    2. Zeifert PD,
    3. Bell-Stephens TE, et al
    . Neurocognitive impairment in adults with Moyamoya disease without stroke. Neurosurgery 2012;70:634–38 doi:10.1227/NEU.0b013e3182320d1a pmid:21849919
    CrossRefPubMed
  3. 3.↵
    1. Kazumata K,
    2. Tha KK,
    3. Narita H, et al
    . Chronic ischemia alters brain microstructural integrity and cognitive performance in adult Moyamoya disease. Stroke 2015;46:354–60 doi:10.1161/STROKEAHA.114.007407 pmid:25538200
    Abstract/FREE Full Text
  4. 4.↵
    1. Tha KK,
    2. Terae S,
    3. Nakagawa S, et al
    . Impaired integrity of the brain parenchyma in non-geriatric patients with major depressive disorder revealed by diffusion tensor imaging. Psychiatry Res 2013;212:208–15 doi:10.1016/j.pscychresns.2012.07.004 pmid:23149032
    CrossRefPubMed
  5. 5.↵
    1. Basser PJ,
    2. Mattiello J,
    3. LeBihan D
    . MR diffusion tensor spectroscopy and imaging. Biophys J 1994;66:259–67 pmid:8130344
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Jensen JH,
    2. Helpern JA,
    3. Ramani A, et al
    . Diffusional kurtosis imaging: the quantification of non-gaussian water diffusion by means of magnetic resonance imaging. Magnetic Reson Med 2005;53:1432–40 pmid:15906300
    CrossRefPubMed
  7. 7.↵
    1. Back SA
    . Cerebral white and gray matter injury in newborns: new insights into pathophysiology and management. Clin Perinatal 2014;41:1–24 doi:10.1016/j.clp.2013.11.001 pmid:24524444
    CrossRefPubMed
  8. 8.↵
    1. Zhang S,
    2. Boyd J,
    3. Delaney K, et al
    . Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia. J Neurosci 2005;25:5333–38 pmid:15930381
    Abstract/FREE Full Text
  9. 9.↵
    1. Fieremans E,
    2. Jensen JH,
    3. Helpern JA
    . White matter characterization with diffusional kurtosis imaging. Neuroimage 2011;58:177–88 doi:10.1016/j.neuroimage.2011.06.006 pmid:21699989
    CrossRefPubMed
  10. 10.↵
    1. Li X,
    2. Gao J,
    3. Hou X, et al
    . Diffusion kurtosis imaging with tract-based spatial statistics reveals white matter alterations in preschool children. Conf Proc IEEE Eng Med Biol Soc 2012;2012:2298–301 doi:10.1109/EMBC.2012.6346422 pmid:23366383
    CrossRefPubMed
  11. 11.↵
    1. Coutu JP,
    2. Chen JJ,
    3. Rosas HD, et al
    . Non-Gaussian water diffusion in aging white matter. Neurobiol Aging 2014;35:1412–21 doi:10.1016/j.neurobiolaging.2013.12.001 pmid:24378085
    CrossRefPubMed
  12. 12.↵
    1. Gong NJ,
    2. Wong CS,
    3. Chan CC, et al
    . Aging in deep gray matter and white matter revealed by diffusional kurtosis imaging. Neurobiol Aging 2014;35:2203–16 doi:10.1016/j.neurobiolaging.2014.03.011 pmid:24910392
    CrossRefPubMed
  13. 13.↵
    1. Caverzasi E,
    2. Henry RG,
    3. Vitali P, et al
    . Application of quantitative DTI metrics in sporadic CJD. Neuroimage Clin 2014;4:426–35 doi:10.1016/j.nicl.2014.01.011 pmid:24624328
    CrossRefPubMed
  14. 14.↵
    1. Weber RA,
    2. Hui ES,
    3. Jensen JH, et al
    . Diffusional kurtosis and diffusion tensor imaging reveal different time-sensitive stroke-induced microstructural changes. Stroke 2015;46:545–50 doi:10.1016/j.nicl.2014.01.011 pmid:25563646
    Abstract/FREE Full Text
  15. 15.↵
    1. Grinberg F,
    2. Farrher E,
    3. Ciobanu L, et al
    . Non-Gaussian diffusion imaging for enhanced contrast of brain tissue affected by ischemic stroke. PLoS One 2014;9:e89225 doi:10.1371/journal.pone.0089225 pmid:24586610
    CrossRefPubMed
  16. 16.↵
    1. Umesh Rudrapatna S,
    2. Wieloch T,
    3. Beirup K, et al
    . Can diffusion kurtosis imaging improve the sensitivity and specificity of detecting microstructural alterations in brain tissue chronically after experimental stroke? Comparisons with diffusion tensor imaging and histology. Neuroimage 2014;97:363–73 doi:10.1016/j.neuroimage.2014.04.013 pmid:24742916
    CrossRefPubMed
  17. 17.↵
    1. Tabesh A,
    2. Jensen JH,
    3. Ardekani BA, et al
    . Estimation of tensors and tensor-derived measures in diffusional kurtosis imaging. Magn Reson Med 2011;65:823–36 doi:10.1002/mrm.22655 pmid:21337412
    CrossRefPubMed
  18. 18.↵
    1. Reijmer YD,
    2. Leemans A,
    3. Heringa SM, et al
    ; Vascular Cognitive Impairment Study group. Improved sensitivity to cerebral white matter abnormalities in Alzheimer's disease with spherical deconvolution based tractography. PLoS One 2012;7:e44074 doi:10.1371/journal.pone.0044074 pmid:22952880
    CrossRefPubMed
  19. 19.↵
    1. Wakana S,
    2. Jiang H,
    3. Nagae-Poetscher LM, et al
    . Fiber tract-based atlas of human white matter anatomy. Radiology 2004;230:77–87 pmid:14645885
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Cheng HL,
    2. Lin CJ,
    3. Soong BW, et al
    . Impairments in cognitive function and brain connectivity in severe asymptomatic carotid stenosis. Stroke 2012;43:2567–73 pmid:22935402
    Abstract/FREE Full Text
  21. 21.↵
    1. Schmidt R,
    2. Seiler S,
    3. Loitfelder M
    . Longitudinal change of small-vessel disease-related brain abnormalities. J Cereb Blood Flow Metab 2015 Apr 22. [Epub ahead of print] doi:10.1038/jcbfm.2015.72 pmid:25899293
    Abstract/FREE Full Text
  22. 22.↵
    1. Kamagata K,
    2. Tomiyama H,
    3. Hatano T, et al
    . A preliminary diffusional kurtosis imaging study of Parkinson disease: comparison with conventional diffusion tensor imaging. Neuroradiology 2014;56:251–58 doi:10.1007/s00234-014-1327-1 pmid:24468858
    CrossRefPubMed
  23. 23.↵
    1. Fieremans E,
    2. Benitez A,
    3. Jensen JH, et al
    . Novel white matter tract integrity metrics sensitive to Alzheimer disease progression. AJNR Am J Neuroradiol 2013;34:2105–12 doi:10.3174/ajnr.A3553 pmid:23764722
    Abstract/FREE Full Text
  24. 24.↵
    1. Steven AJ,
    2. Zhuo J,
    3. Melhem ER
    . Diffusion kurtosis imaging: an emerging technique for evaluating the microstructural environment of the brain. AJR Am J Roentgenol 2014;202:W26–33 doi:10.2214/AJR.13.11365 pmid:24370162
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Cechetti F,
    2. Pagnussat AS,
    3. Worm PV, et al
    . Chronic brain hypoperfusion causes early glial activation and neuronal death, and subsequent long-term memory impairment. Brain Res Bull 2012;87:109–16 doi:10.1016/j.brainresbull.2011.10.006 pmid:22040859
    CrossRefPubMedWeb of Science
  26. 26.↵
    1. Jbabdi S,
    2. Behrens TE,
    3. Smith SM
    . Crossing fibres in tract-based spatial statistics. Neuroimage 2010;49:249–56 doi:10.1016/j.neuroimage.2009.08.039 pmid:19712743
    CrossRefPubMed
  27. 27.↵
    1. Gläscher J,
    2. Rudrauf D,
    3. Colom R, et al
    . Distributed neural system for general intelligence revealed by lesion mapping. Proc Natl Acad Sci U S A 2010;107:4705–09 doi:10.1073/pnas.0910397107 pmid:20176936
    Abstract/FREE Full Text
  28. 28.↵
    1. Deary IJ,
    2. Weiss A,
    3. Batty GD
    . Intelligence and personality as predictors of illness and death: how researchers in differential psychology and chronic disease epidemiology are collaborating to understand and address health inequalities. Psychol Sci Public Interest 2010;11:53–79 doi:10.1177/1529100610387081 pmid:26168413
    FREE Full Text
  29. 29.↵
    1. Barbey AK,
    2. Colom R,
    3. Solomon J, et al
    . An integrative architecture for general intelligence and executive function revealed by lesion mapping. Brain 2012;135:1154–64 doi:10.1093/brain/aws021 pmid:22396393
    Abstract/FREE Full Text
  30. 30.↵
    1. Kurumatani T,
    2. Kudo T,
    3. Ikura Y, et al
    . White matter changes in the gerbil brain under chronic cerebral hypoperfusion. Stroke 1998;29:1058–62 pmid:9596257
    Abstract/FREE Full Text
  31. 31.↵
    1. Lin CS,
    2. Polsky K,
    3. Nadler JV, et al
    . Selective neocortical and thalamic cell death in the gerbil after transient ischemia. Neuroscience 1990;35:289–99 pmid:2381510
    CrossRefPubMedWeb of Science
  32. 32.↵
    1. Fukuda A,
    2. Muramatsu K,
    3. Okabe A, et al
    . NMDA receptor-mediated differential laminar susceptibility to the intracellular Ca2+ accumulation induced by oxygen-glucose deprivation in rat neocortical slices. J Neurophysiol 1998;79:430–38 pmid:9425211
    Abstract/FREE Full Text
  33. 33.↵
    1. Yang AW,
    2. Jensen JH,
    3. Hu CC, et al
    . Effect of cerebral spinal fluid suppression for diffusional kurtosis imaging. J Magn Reson Imaging 2013;37:365–71 doi:10.1002/jmri.23840 pmid:23034866
    CrossRefPubMed
  34. 34.↵
    1. Jelescu IO,
    2. Veraart J,
    3. Adisetiyo V, et al
    . One diffusion acquisition and different white matter models: how does microstructure change in human early development based on WMTI and NODDI? Neuroimage 2015;107:242–56 doi:10.1016/j.neuroimage.2014.12.009 pmid:25498427
    CrossRefPubMed
  35. 35.↵
    1. Zhang H,
    2. Schneider T,
    3. Wheeler-Kingshott CA, et al
    . NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain. Neuroimage 2012;61:1000–16 doi:10.1016/j.neuroimage.2012.03.072 pmid:22484410
    CrossRefPubMed
  36. 36.↵
    1. Ferguson BR,
    2. Gao WJ
    . Development of thalamocortical connections between the mediodorsal thalamus and the prefrontal cortex and its implication in cognition. Front Hum Neurosci 2014;8:1027 pmid:25620923
    PubMed
  37. 37.↵
    1. Szczepankiewicz F,
    2. Lätt J,
    3. Wirestam R, et al
    . Variability in diffusion kurtosis imaging: impact on study design, statistical power and interpretation. Neuroimage 2013;76:145–54 doi:10.1016/j.neuroimage.2013.02.078 pmid:23507377
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 37 (8)
American Journal of Neuroradiology
Vol. 37, Issue 8
1 Aug 2016
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Characteristics of Diffusional Kurtosis in Chronic Ischemia of Adult Moyamoya Disease: Comparing Diffusional Kurtosis and Diffusion Tensor Imaging
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
K. Kazumata, K.K. Tha, H. Narita, Y.M. Ito, H. Shichinohe, M. Ito, H. Uchino, T. Abumiya
Characteristics of Diffusional Kurtosis in Chronic Ischemia of Adult Moyamoya Disease: Comparing Diffusional Kurtosis and Diffusion Tensor Imaging
American Journal of Neuroradiology Aug 2016, 37 (8) 1432-1439; DOI: 10.3174/ajnr.A4728

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Characteristics of Diffusional Kurtosis in Chronic Ischemia of Adult Moyamoya Disease: Comparing Diffusional Kurtosis and Diffusion Tensor Imaging
K. Kazumata, K.K. Tha, H. Narita, Y.M. Ito, H. Shichinohe, M. Ito, H. Uchino, T. Abumiya
American Journal of Neuroradiology Aug 2016, 37 (8) 1432-1439; DOI: 10.3174/ajnr.A4728
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Myelin and Axonal Damage in Normal-Appearing White Matter in Patients with Moyamoya Disease
  • MR Diffusional Kurtosis Imaging-Based Assessment of Brain Microstructural Changes in Patients with Moyamoya Disease before and after Revascularization
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Diagnostic Neuroradiology of Monoclonal Antibodies
  • NCCT vs. MRI for Brain Atrophy in Acute Stroke
  • Clinical Outcomes After Chiari I Decompression
Show more Adult Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire