Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in
  • Log out

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in
  • Log out

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatrics
Open Access

A Prospective Longitudinal Brain Morphometry Study of Children with Sickle Cell Disease

R. Chen, M. Arkuszewski, J. Krejza, R.A. Zimmerman, E.H. Herskovits and E.R. Melhem
American Journal of Neuroradiology February 2015, 36 (2) 403-410; DOI: https://doi.org/10.3174/ajnr.A4101
R. Chen
aFrom the Department of Diagnostic Radiology and Nuclear Medicine (R.C., J.K., E.H.H., E.R.M.), University of Maryland, Baltimore, Maryland
dDepartment of Radiology (R.C., R.A.Z.), Raymond and Ruth Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Arkuszewski
bDepartment of Neurology (M.A.), Medical University of Silesia, Katowice, Poland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
J. Krejza
aFrom the Department of Diagnostic Radiology and Nuclear Medicine (R.C., J.K., E.H.H., E.R.M.), University of Maryland, Baltimore, Maryland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R.A. Zimmerman
cDepartment of Radiology (R.A.Z.), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
dDepartment of Radiology (R.C., R.A.Z.), Raymond and Ruth Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
E.H. Herskovits
aFrom the Department of Diagnostic Radiology and Nuclear Medicine (R.C., J.K., E.H.H., E.R.M.), University of Maryland, Baltimore, Maryland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
E.R. Melhem
aFrom the Department of Diagnostic Radiology and Nuclear Medicine (R.C., J.K., E.H.H., E.R.M.), University of Maryland, Baltimore, Maryland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Information

vol. 36 no. 2 403-410
DOI 
https://doi.org/10.3174/ajnr.A4101
PubMed 
25234033

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received May 14, 2014
  • Accepted after revision July 16, 2014
  • Published online February 11, 2015.

Article Versions

  • Latest version (September 18, 2014 - 06:57).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2015 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org

Author Information

  1. R. Chena,d,
  2. M. Arkuszewskib,
  3. J. Krejzaa,
  4. R.A. Zimmermanc,d,
  5. E.H. Herskovitsa and
  6. E.R. Melhema
  1. aFrom the Department of Diagnostic Radiology and Nuclear Medicine (R.C., J.K., E.H.H., E.R.M.), University of Maryland, Baltimore, Maryland
  2. bDepartment of Neurology (M.A.), Medical University of Silesia, Katowice, Poland
  3. cDepartment of Radiology (R.A.Z.), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
  4. dDepartment of Radiology (R.C., R.A.Z.), Raymond and Ruth Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  1. Please address correspondence to Rong Chen, PhD, MTR, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, 22 South Greene St, Baltimore, MD 21201; e-mail: rchen{at}umm.edu
View Full Text

Altmetrics

Cited By...

  • 23 Citations
  • 22 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease
    Melanie E. Fields, Kristin P. Guilliams, Dustin K. Ragan, Michael M. Binkley, Cihat Eldeniz, Yasheng Chen, Monica L. Hulbert, Robert C. McKinstry, Joshua S. Shimony, Katie D. Vo, Allan Doctor, Hongyu An, Andria L. Ford, Jin-Moo Lee
    Neurology 2018 90 13
  • Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia
    Melanie E. Fields, Kristin P. Guilliams, Dustin Ragan, Michael M. Binkley, Amy Mirro, Slim Fellah, Monica L. Hulbert, Morey Blinder, Cihat Eldeniz, Katie Vo, Joshua S. Shimony, Yasheng Chen, Robert C. McKinstry, Hongyu An, Jin-Moo Lee, Andria L. Ford
    Blood 2019 133 22
  • Vascular Instability and Neurological Morbidity in Sickle Cell Disease: An Integrative Framework
    Hanne Stotesbury, Jamie M. Kawadler, Patrick W. Hales, Dawn E. Saunders, Christopher A. Clark, Fenella J. Kirkham
    Frontiers in Neurology 2019 10
  • Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy
    Kristin P. Guilliams, Melanie E. Fields, Dustin K. Ragan, Yasheng Chen, Cihat Eldeniz, Monica L. Hulbert, Michael M. Binkley, James N. Rhodes, Joshua S. Shimony, Robert C. McKinstry, Katie D. Vo, Hongyu An, Jin-Moo Lee, Andria L. Ford
    Pediatric Neurology 2017 69
  • Hemoglobin and mean platelet volume predicts diffuse T1-MRI white matter volume decrease in sickle cell disease patients
    Soyoung Choi, Adam M. Bush, Matthew T. Borzage, Anand A. Joshi, William J. Mack, Thomas D. Coates, Richard M. Leahy, John C. Wood
    NeuroImage: Clinical 2017 15
  • Contrasting resting-state fMRI abnormalities from sickle and non-sickle anemia
    Julie Coloigner, Yeun Kim, Adam Bush, Soyoung Choi, Melissa C. Balderrama, Thomas D. Coates, Sharon H. O’Neil, Natasha Lepore, John C. Wood, Andrea Kassner
    PLOS ONE 2017 12 10
  • Neuroimaging in Sickle Cell Disease: A Review
    Dermot Mallon, David Doig, Luke Dixon, Anastasia Gontsarova, Wajanat Jan, Francesca Tona
    Journal of Neuroimaging 2020 30 6
  • MRI detection of brain abnormality in sickle cell disease
    Hanne Stotesbury, Jamie Michelle Kawadler, Dawn Elizabeth Saunders, Fenella Jane Kirkham
    Expert Review of Hematology 2021 14 5
  • Functional Connectivity Decreases with Metabolic Stress in Sickle Cell Disease
    Melanie E. Fields, Amy E. Mirro, Kristin P. Guilliams, Michael M. Binkley, Luisa Gil Diaz, Jessica Tan, Slim Fellah, Cihat Eldeniz, Yasheng Chen, Andria L. Ford, Joshua S. Shimony, Allison A. King, Hongyu An, Christopher D. Smyser, Jin‐Moo Lee
    Annals of Neurology 2020 88 5
  • Graph Lasso-Based Test for Evaluating Functional Brain Connectivity in Sickle Cell Disease
    Julie Coloigner, Ronald Phlypo, Thomas D. Coates, Natasha Lepore, John C. Wood
    Brain Connectivity 2017 7 7
  • Brain morphometric analysis predicts decline of intelligence quotient in children with sickle cell disease: A preliminary study
    Rong Chen, Jaroslaw Krejza, Michal Arkuszewski, Robert A. Zimmerman, Edward H. Herskovits, Elias R. Melhem
    Advances in Medical Sciences 2017 62 1
  • Progressive loss of brain volume in children with sickle cell anemia and silent cerebral infarct: A report from the silent cerebral infarct transfusion trial
    Deepika S. Darbari, Odianosen Eigbire‐Molen, Maria R. Ponisio, Mikhail V. Milchenko, Mark J. Rodeghier, James F. Casella, Robert C. McKinstry, Michael R. DeBaun
    American Journal of Hematology 2018 93 12
  • Conventional and advanced brain MR imaging in patients with sickle cell anemia
    Pratibha Issar, Maya Nehra, Gurmeet Singh, SK Issar
    Indian Journal of Radiology and Imaging 2018 28 03
  • Dynamic network model with continuous valued nodes for longitudinal brain morphometry
    Rong Chen, Yuanjie Zheng, Erika Nixon, Edward H. Herskovits
    NeuroImage 2017 155
  • Effects of regional brain volumes on cognition in sickle cell anemia: A developmental perspective
    Shifa Hamdule, Melanie Kölbel, Hanne Stotesbury, Russell Murdoch, Jonathan D. Clayden, Sati Sahota, Anna Marie Hood, Christopher A. Clark, Fenella Jane Kirkham
    Frontiers in Neurology 2023 14
  • Brain volume in Tanzanian children with sickle cell anaemia: A neuroimaging study
    Mboka Jacob, Jamie M. Kawadler, Russell Murdoch, Magda Ahmed, Hilda Tutuba, Upendo Masamu, Karin Shmueli, Dawn E. Saunders, Chris A. Clark, Jinna Kim, Shifa Hamdule, Julie Makani, Hanne Stotesbury, Fenella J. Kirkham
    British Journal of Haematology 2023 201 1
  • Neuroimaging and Cognitive Function in Sickle Cell Disease: A Systematic Review
    Suad S. Abdi, Michelle De Haan, Fenella J. Kirkham
    Children 2023 10 3
  • Brain Volumes and Cognition in Patients with Sickle Cell Anaemia: A Systematic Review and Meta-Analysis
    Shifa Hamdule, Fenella J. Kirkham
    Children 2023 10 8
  • Neurovascular Manifestations of Sickle Cell Disease
    Marialuisa Zedde, Micol Quaresima, Isabella Capodanno, Ilaria Grisendi, Federica Assenza, Manuela Napoli, Claudio Moratti, Claudio Pavone, Lara Bonacini, Giovanna Di Cecco, Serena D’Aniello, Franco Valzania, Francesco Merli, Rosario Pascarella
    Hemato 2024 5 3
  • Diagnostic Imaging: Pädiatrische Neuroradiologie
    Luke L. Linscott, Anna Illner, Eberhard Siebert
    2023
  • Neurologic and Cognitive Outcomes in Sickle Cell Disease from Infancy through Adolescence
    Sarah L. Mayer, Melanie E. Fields, Monica L. Hulbert
    NeoReviews 2021 22 8
  • Personalizing transfusion in sickle cell disease: where is the canary in the mine?
    Melanie E. Fields
    Transfusion 2019 59 8
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 36 (2)
American Journal of Neuroradiology
Vol. 36, Issue 2
1 Feb 2015
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
A Prospective Longitudinal Brain Morphometry Study of Children with Sickle Cell Disease
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
R. Chen, M. Arkuszewski, J. Krejza, R.A. Zimmerman, E.H. Herskovits, E.R. Melhem
A Prospective Longitudinal Brain Morphometry Study of Children with Sickle Cell Disease
American Journal of Neuroradiology Feb 2015, 36 (2) 403-410; DOI: 10.3174/ajnr.A4101

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
A Prospective Longitudinal Brain Morphometry Study of Children with Sickle Cell Disease
R. Chen, M. Arkuszewski, J. Krejza, R.A. Zimmerman, E.H. Herskovits, E.R. Melhem
American Journal of Neuroradiology Feb 2015, 36 (2) 403-410; DOI: 10.3174/ajnr.A4101
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Neurologic and Cognitive Outcomes in Sickle Cell Disease from Infancy through Adolescence
  • Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia
  • Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease
  • Crossref (22)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease
    Melanie E. Fields, Kristin P. Guilliams, Dustin K. Ragan, Michael M. Binkley, Cihat Eldeniz, Yasheng Chen, Monica L. Hulbert, Robert C. McKinstry, Joshua S. Shimony, Katie D. Vo, Allan Doctor, Hongyu An, Andria L. Ford, Jin-Moo Lee
    Neurology 2018 90 13
  • Hydroxyurea reduces cerebral metabolic stress in patients with sickle cell anemia
    Melanie E. Fields, Kristin P. Guilliams, Dustin Ragan, Michael M. Binkley, Amy Mirro, Slim Fellah, Monica L. Hulbert, Morey Blinder, Cihat Eldeniz, Katie Vo, Joshua S. Shimony, Yasheng Chen, Robert C. McKinstry, Hongyu An, Jin-Moo Lee, Andria L. Ford
    Blood 2019 133 22
  • Vascular Instability and Neurological Morbidity in Sickle Cell Disease: An Integrative Framework
    Hanne Stotesbury, Jamie M. Kawadler, Patrick W. Hales, Dawn E. Saunders, Christopher A. Clark, Fenella J. Kirkham
    Frontiers in Neurology 2019 10
  • Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy
    Kristin P. Guilliams, Melanie E. Fields, Dustin K. Ragan, Yasheng Chen, Cihat Eldeniz, Monica L. Hulbert, Michael M. Binkley, James N. Rhodes, Joshua S. Shimony, Robert C. McKinstry, Katie D. Vo, Hongyu An, Jin-Moo Lee, Andria L. Ford
    Pediatric Neurology 2017 69
  • Hemoglobin and mean platelet volume predicts diffuse T1-MRI white matter volume decrease in sickle cell disease patients
    Soyoung Choi, Adam M. Bush, Matthew T. Borzage, Anand A. Joshi, William J. Mack, Thomas D. Coates, Richard M. Leahy, John C. Wood
    NeuroImage: Clinical 2017 15
  • Contrasting resting-state fMRI abnormalities from sickle and non-sickle anemia
    Julie Coloigner, Yeun Kim, Adam Bush, Soyoung Choi, Melissa C. Balderrama, Thomas D. Coates, Sharon H. O’Neil, Natasha Lepore, John C. Wood, Andrea Kassner
    PLOS ONE 2017 12 10
  • Neuroimaging in Sickle Cell Disease: A Review
    Dermot Mallon, David Doig, Luke Dixon, Anastasia Gontsarova, Wajanat Jan, Francesca Tona
    Journal of Neuroimaging 2020 30 6
  • MRI detection of brain abnormality in sickle cell disease
    Hanne Stotesbury, Jamie Michelle Kawadler, Dawn Elizabeth Saunders, Fenella Jane Kirkham
    Expert Review of Hematology 2021 14 5
  • Functional Connectivity Decreases with Metabolic Stress in Sickle Cell Disease
    Melanie E. Fields, Amy E. Mirro, Kristin P. Guilliams, Michael M. Binkley, Luisa Gil Diaz, Jessica Tan, Slim Fellah, Cihat Eldeniz, Yasheng Chen, Andria L. Ford, Joshua S. Shimony, Allison A. King, Hongyu An, Christopher D. Smyser, Jin‐Moo Lee
    Annals of Neurology 2020 88 5
  • Graph Lasso-Based Test for Evaluating Functional Brain Connectivity in Sickle Cell Disease
    Julie Coloigner, Ronald Phlypo, Thomas D. Coates, Natasha Lepore, John C. Wood
    Brain Connectivity 2017 7 7

More in this TOC Section

  • SyMRI & MR Fingerprinting in Brainstem Myelination
  • Comparison of Image Quality and Radiation Dose in Pediatric Temporal Bone CT Using Photon-Counting Detector CT and Energy-Integrating Detector CT
  • Dandy-Walker Phenotype with Brainstem Involvement
Show more Pediatrics

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire