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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleAdult Brain

Brain Magnetic Susceptibility Changes in Patients with Natalizumab-Associated Progressive Multifocal Leukoencephalopathy

J. Hodel, O. Outteryck, S. Verclytte, V. Deramecourt, A. Lacour, J.-P. Pruvo, P. Vermersch and X. Leclerc
American Journal of Neuroradiology December 2015, 36 (12) 2296-2302; DOI: https://doi.org/10.3174/ajnr.A4436
J. Hodel
aFrom the University of Lille, CHU Lille (J.H., O.O., V.D., A.L., J.-P.P., P.V., X.L.), Lille, France
bDepartments of Neuroradiology (J.H., J.-P.P., X.L.)
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O. Outteryck
aFrom the University of Lille, CHU Lille (J.H., O.O., V.D., A.L., J.-P.P., P.V., X.L.), Lille, France
cNeurology (O.O., A.L., P.V.), Roger Salengro Hospital, Lille, France
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S. Verclytte
dDepartment of Radiology (S.V.), Saint Philibert Hospital, Lille, France
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V. Deramecourt
aFrom the University of Lille, CHU Lille (J.H., O.O., V.D., A.L., J.-P.P., P.V., X.L.), Lille, France
eDepartment of Pathology (V.D.), Lille University Hospital, Lille, France.
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A. Lacour
aFrom the University of Lille, CHU Lille (J.H., O.O., V.D., A.L., J.-P.P., P.V., X.L.), Lille, France
cNeurology (O.O., A.L., P.V.), Roger Salengro Hospital, Lille, France
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J.-P. Pruvo
aFrom the University of Lille, CHU Lille (J.H., O.O., V.D., A.L., J.-P.P., P.V., X.L.), Lille, France
bDepartments of Neuroradiology (J.H., J.-P.P., X.L.)
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P. Vermersch
aFrom the University of Lille, CHU Lille (J.H., O.O., V.D., A.L., J.-P.P., P.V., X.L.), Lille, France
cNeurology (O.O., A.L., P.V.), Roger Salengro Hospital, Lille, France
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X. Leclerc
aFrom the University of Lille, CHU Lille (J.H., O.O., V.D., A.L., J.-P.P., P.V., X.L.), Lille, France
bDepartments of Neuroradiology (J.H., J.-P.P., X.L.)
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REFERENCES

  1. 1.↵
    1. Clifford DB,
    2. De Luca A,
    3. Simpson DM, et al
    . Natalizumab-associated progressive multifocal leukoencephalopathy in patients with multiple sclerosis: lessons from 28 cases. Lancet Neurol 2010;9:438–46 doi:10.1016/S1474-4422(10)70028-4 pmid:20298967
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Dong-Si T,
    2. Richman S,
    3. Wattjes MP, et al
    . Outcome and survival of asymptomatic PML in natalizumab-treated MS patients. Ann Clin Transl Neurol 2014;1:755–64 doi:10.1002/acn3.114 pmid:25493267
    CrossRefPubMed
  3. 3.↵
    1. Wattjes MP,
    2. Richert ND,
    3. Killestein J, et al
    . The chameleon of neuroinflammation: magnetic resonance imaging characteristics of natalizumab-associated progressive multifocal leukoencephalopathy. Mult Scler 2013;19:1826–40 doi:10.1177/1352458513510224 pmid:24192217
    Abstract/FREE Full Text
  4. 4.↵
    1. Wattjes MP,
    2. Vennegoor A,
    3. Steenwijk MD, et al
    . MRI pattern in asymptomatic natalizumab-associated PML. J Neurol Neurosurg Psychiatry 2015;86:793–98 doi:10.1136/jnnp-2014-308630 pmid:25205744
    Abstract/FREE Full Text
  5. 5.↵
    1. Yousry TA,
    2. Pelletier D,
    3. Cadavid D, et al
    . Magnetic resonance imaging pattern in natalizumab-associated progressive multifocal leukoencephalopathy. Ann Neurol 2012;72:779–87 doi:10.1002/ana.23676 pmid:23280794
    CrossRefPubMed
  6. 6.↵
    1. Blair NF,
    2. Brew BJ,
    3. Halpern JP
    . Natalizumab-associated PML identified in the presymptomatic phase using MRI surveillance. Neurology 2012;78:507–08 doi:10.1212/WNL.0b013e318246d6d8 pmid:22302545
    FREE Full Text
  7. 7.↵
    1. Bag AK,
    2. Curé JK,
    3. Chapman PR, et al
    . JC virus infection of the brain. AJNR Am J Neuroradiol 2010;31:1564–76 doi:10.3174/ajnr.A2035 pmid:20299430
    Abstract/FREE Full Text
  8. 8.↵
    1. Wattjes MP,
    2. Verhoeff L,
    3. Zentjens W, et al
    . Punctate lesion pattern suggestive of perivascular inflammation in acute natalizumab-associated progressive multifocal leukoencephalopathy: productive JC virus infection or preclinical PML-IRIS manifestation? J Neurol Neurosurg Psychiatry 2013;84:1176–77 doi:10.1136/jnnp-2013-304986 pmid:23695498
    FREE Full Text
  9. 9.↵
    1. Berger JR,
    2. Aksamit AJ,
    3. Clifford DB, et al
    . PML diagnostic criteria: consensus statement from the AAN Neuroinfectious Disease Section. Neurology 2013;80:1430–38 doi:10.1212/WNL.0b013e31828c2fa1 pmid:23568998
    Abstract/FREE Full Text
  10. 10.↵
    1. Rudko DA,
    2. Solovey I,
    3. Gati JS, et al
    . Multiple sclerosis: improved identification of disease-relevant changes in gray and white matter by using susceptibility-based MR imaging. Radiology 2014;272:851–64 doi:10.1148/radiol.14132475 pmid:24828000
    CrossRefPubMed
  11. 11.↵
    1. Major EO,
    2. Ault GS
    . Progressive multifocal leukoencephalopathy: clinical and laboratory observations on a viral induced demyelinating disease in the immunodeficient patient. Curr Opin Neurol 1995;8:184–90 doi:10.1097/00019052-199506000-00006 pmid:7551117
    CrossRefPubMedWeb of Science
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American Journal of Neuroradiology: 36 (12)
American Journal of Neuroradiology
Vol. 36, Issue 12
1 Dec 2015
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Cite this article
J. Hodel, O. Outteryck, S. Verclytte, V. Deramecourt, A. Lacour, J.-P. Pruvo, P. Vermersch, X. Leclerc
Brain Magnetic Susceptibility Changes in Patients with Natalizumab-Associated Progressive Multifocal Leukoencephalopathy
American Journal of Neuroradiology Dec 2015, 36 (12) 2296-2302; DOI: 10.3174/ajnr.A4436

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Brain Magnetic Susceptibility Changes in Patients with Natalizumab-Associated Progressive Multifocal Leukoencephalopathy
J. Hodel, O. Outteryck, S. Verclytte, V. Deramecourt, A. Lacour, J.-P. Pruvo, P. Vermersch, X. Leclerc
American Journal of Neuroradiology Dec 2015, 36 (12) 2296-2302; DOI: 10.3174/ajnr.A4436
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  • Current and Emerging Therapies in Multiple Sclerosis: Implications for the Radiologist, Part 2--Surveillance for Treatment Complications and Disease Progression
  • Low Signals on T2* and SWI Sequences in Patients with MS with Progressive Multifocal Leukoencephalopathy
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