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Research ArticleNeurointervention

Effects of Circle of Willis Anatomic Variations on Angiographic and Clinical Outcomes of Coiled Anterior Communicating Artery Aneurysms

E. Tarulli, M. Sneade, A. Clarke, A.J. Molyneux and A.J. Fox
American Journal of Neuroradiology August 2014, 35 (8) 1551-1555; DOI: https://doi.org/10.3174/ajnr.A3991
E. Tarulli
aFrom the Department of Medical Imaging (E.T., A.J.F.), University of Toronto, Ontario, Canada
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M. Sneade
bOxford Neurovascular and Neuroradiology Research Unit (M.S., A.C., A.J.M.), University of Oxford, Oxford, UK.
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A. Clarke
bOxford Neurovascular and Neuroradiology Research Unit (M.S., A.C., A.J.M.), University of Oxford, Oxford, UK.
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A.J. Molyneux
bOxford Neurovascular and Neuroradiology Research Unit (M.S., A.C., A.J.M.), University of Oxford, Oxford, UK.
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A.J. Fox
aFrom the Department of Medical Imaging (E.T., A.J.F.), University of Toronto, Ontario, Canada
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    Fig 1.

    DSA studies showing examples of A1 segment categories with white and black arrows indicating right and left A1, respectively, for codominant (A) and dominant (B and C) configurations. Panels B and C demonstrate A1 dominant cases with diminutive and absent contralateral A1 segments, respectively.

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    Fig 2.

    Anatomic dimensions of aneurysm neck width and remnants taken at baseline and follow-up imaging. All cases with available measurements in each group were included regardless of angiographic classification as listed in Table 1. The A1-dominant AcomA aneurysm group had a larger mean neck width at baseline and more variance in neck remnant at follow-up, P = .03 and .01 by *t test and **F test, respectively.

Tables

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    Table 1:

    Angiographic classification data

    Angiographic OcclusionBaseline Post-Coiling5–7 Month Follow-Up
    AcomA Aneurysm A1 Codominant (n = 33), No. (%)AcomA Aneurysm A1 Dominant (n = 91), No. (%)Basilar/MCA Termination Aneurysms (n = 89), No. (%)AcomA Aneurysm A1 Codominant (n = 31), No. (%)AcomA Aneurysm A1 Dominant (n = 86), No. (%)Basilar/MCA Termination Aneurysms (n = 78), No. (%)
    Complete12 (36%)48 (53%)45 (50%)13 (42%)34 (40%)22 (28%)
    Neck remnant16 (49%)32 (35%)29 (33%)11 (35%)31 (36%)41 (53%)
    Sac filling5 (15%)11 (12%)15 (17%)7 (23%)21 (24%)15 (19%)
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    Table 2:

    CCT definition of success at 5–7 months

    Angiographic Occlusion at First Follow-UpAcomA Aneurysm A1 Co-Dominant (n = 31), No. (%)AcomA Aneurysm A1 Dominant (n = 86), No. (%)
    Complete13 (42%)29 (34%)
    Stable0 (0%)3 (3%)
    Improved6 (19%)17 (20%)
    Totala19 (61%)49 (57%)
    • ↵a There were 12 (39%) and 37 (43%) from each group that did not meet the CCT definition of success at 5–7 month follow-up.

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    Table 3:

    Change in angiographic appearance from baseline to first follow-up

    Baseline (n = 31a)
    Complete (n = 12)Neck Remnant (n = 15)Sac Filling (n = 4)
    A1 Codominant
        First follow-up (n = 31)
            Complete (n = 13)940
            Neck remnant (n = 11)191
            Sac filling (n = 7)223
    Baseline (n = 86a)
    Complete (n = 47)Neck Remnant (n = 30)Sac Filling (n = 9)
    A1 Dominant
        First follow-up (n = 86)
            Complete (n = 34)2671
            Neck remnant (n = 31)8185
            Sac filling (n = 21)1353
    • ↵a Only baseline cases with follow-up data were included (31 of 33 and 86 of 91).

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American Journal of Neuroradiology: 35 (8)
American Journal of Neuroradiology
Vol. 35, Issue 8
1 Aug 2014
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Cite this article
E. Tarulli, M. Sneade, A. Clarke, A.J. Molyneux, A.J. Fox
Effects of Circle of Willis Anatomic Variations on Angiographic and Clinical Outcomes of Coiled Anterior Communicating Artery Aneurysms
American Journal of Neuroradiology Aug 2014, 35 (8) 1551-1555; DOI: 10.3174/ajnr.A3991

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Effects of Circle of Willis Anatomic Variations on Angiographic and Clinical Outcomes of Coiled Anterior Communicating Artery Aneurysms
E. Tarulli, M. Sneade, A. Clarke, A.J. Molyneux, A.J. Fox
American Journal of Neuroradiology Aug 2014, 35 (8) 1551-1555; DOI: 10.3174/ajnr.A3991
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