Association between Resting-State Coactivation in the Parieto-Frontal Network and Intelligence during Late Childhood and Adolescence

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Fig 1.
Spatial maps representing the parieto-frontal networks on the basis of temporal-concatenation group independent component analyses.
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Fig 2.
Positive correlations with full-scale intelligence quotient (FSIQ) across subjects. In the right parieto-frontal network (R.PFN) of children, significant correlations were observed in the right angular gyrus (AG) (a) and inferior frontal gyrus (IFG) (b), and marginally significant correlations were observed in the left cerebellum (c) and another right AG region (d). In adolescents, significant correlations were observed in the left IFG in the left PFN (L.PFN) (e), and marginally significant correlations were observed in the left frontal pole (FP) in the L.PFN (f) and right FP in the R.PFN (g). Green color indicates significant correlations and red-yellow color indicates marginally significant correlations. In the scatterplots, the y-coordinate indicates the mean coactivation of voxels exhibiting significant spatial map–versus–FSIQ correlations.

Positive correlations with FSIQ across subjects

Region	Brodmann Area	Cluster Size, mm³	MNI Coordinate (Peak)	r Value (mean)
Children:
Correlations with FSIQ in the R.PFN
R AG	39	184	40, −66, 56	0.45
R AG	39	1656^{^b}	40, −66, 56	0.45
R IFG	44	128	52, 12, 28	0.41
R IFG	44	1616^{^b}	52, 12, 28	0.41
L cerebellum^{^a}		536^{^b}	−36, −74, −50	0.37
R AG^{^a}	39	280^{^b}	32, −80, 38	0.27
Adolescents:
Correlations with FSIQ in the L.PFN
L IFG	45	256	−42, 34, 6	0.54
L IFG	45	2416^{^b}	−42, 34, 6	0.54
L FP^{^a}	10	360^{^b}	−22, 60, 2	0.37
Correlations with FSIQ in the R.PFN
R FP^{^a}	11	528^{^b}	30, 56, −4	0.43

Note:—Threshold was P < .05 (threshold-free cluster enhanced, family-wise error–corrected).
↵a Marginally significant correlations (uncorrected P < .005 and cluster size >200 mm³);
↵b represents the cluster size at this threshold. No marginally significant correlation was found in the L.PFN of children.
R indicates right; L, left; IFG, inferior frontal gyrus; AG, angular gyrus; FP, frontal pole; MNI, Montreal Neurological Institute.