Article Figures & Data
Figures
- Fig 1.
FLAIR image just above ventricles shows punctuate and confluent white matter T2 hyperintensities. From left to right: juxtacortical punctate, juxtacortical confluent, periventricular punctate, and central punctate.
- Fig 2.
Probability value of correlation between Vitamin D level and white matter T2 hyperintensities in subjects without vitamin D supplementation by lesion location and type (n = 17, age >50 years). Bar height represents P value of relationship between WMH and serum 25-hydroxyvitamin D. Bars lower than the horizontal line are less than .05 and are significant. Correlation coefficient (r) value is shown above each bar. Red bars are punctate lesions, green bars are confluent lesions by size, and blue bars are confluent lesion number. J indicates juxtacortical; C, central; and P, periventricular.
Tables
Age, Years n Vit D <20 Vit D ≥20 31–49; mean, 38.2 22 10 (7 female, 3 male) 12 (11 female, 1 male) 7 white, 3 black 12 white 1 hypertensive, 1 diabetic 2 hypertensive, 2 diabetic 1 supplemental vitamin D 8 supplemental vitamin D 50–69; mean, 59.5 25 11 (7 female, 4 male) 14 (11 female, 3 male) 7 white, 4 black 13 white, 1 black 8 hypertensive (2 uncontrolled) 10 hypertensive (2 uncontrolled) 4 diabetic (1 uncontrolled) 3 diabetic (1 uncontrolled) 1 supplemental vitamin D 7 supplemental vitamin D WMH Region Correlation Coefficient P Value Punctate lesions Juxtacortical −0.283 .054 Central −0.409 .004 Periventricular −0.359 .013 Confluent lesions Juxtacortical −0.235 .112 Central −0.214 .148 Periventricular −0.321 .028 No. of lesions Juxtacortical −0.199 .180 Central −0.228 .123 Periventricular −0.301 .040 WMH Region Age Diabetes Hypertension Correlation Coefficient P Value Correlation Coefficient P Value Correlation Coefficient P Value Punctate lesions Juxtacortical 0.364 .012 0.129 .389 0.331 .023 Central 0.540 0 0.317 .03 0.476 .001 Periventricular 0.468 .001 0.324 .026 0.345 .018 Confluent lesions Juxtacortical 0.277 .06 0.297 .042 0.274 .062 Central 0.410 .004 0.185 .212 0.226 .127 Periventricular 0.536 0 0.226 .126 0.467 .001 No. of lesions Juxtacortical 0.205 .168 0.113 .451 0.289 .049 Central 0.353 .015 0.269 .067 0.263 .074 Periventricular 0.471 .001 0.232 .117 0.385 .008 WMH Region κ Value P Value Punctate lesions Juxtacortical 0.399 <.001 Central 0.394 <.001 Periventricular 0.215 <.001 Confluent lesions Juxtacortical 0.261 <.001 Central 0.125 .031 Periventricular 0.305 <.001 No. of lesions Juxtacortical 0.532 <.001 Central 0.206 .003 Periventricular 0.44 <.001
