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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePatient Safety

Radiation Dose Reduction in Paranasal Sinus CT Using Model-Based Iterative Reconstruction

J.M. Hoxworth, D. Lal, G.P. Fletcher, A.C. Patel, M. He, R.G. Paden and A.K. Hara
American Journal of Neuroradiology April 2014, 35 (4) 644-649; DOI: https://doi.org/10.3174/ajnr.A3749
J.M. Hoxworth
aFrom the Departments of Radiology (J.M.H., G.P.F., A.C.P., R.G.P, A.K.H.)
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D. Lal
bOtolaryngology (D.L.), Mayo Clinic, Phoenix, Arizona
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G.P. Fletcher
aFrom the Departments of Radiology (J.M.H., G.P.F., A.C.P., R.G.P, A.K.H.)
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A.C. Patel
aFrom the Departments of Radiology (J.M.H., G.P.F., A.C.P., R.G.P, A.K.H.)
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M. He
cSchool of Computing, Informatics, and Decision Systems Engineering, (M.H.), Arizona State University, Tempe, Arizona.
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R.G. Paden
aFrom the Departments of Radiology (J.M.H., G.P.F., A.C.P., R.G.P, A.K.H.)
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A.K. Hara
aFrom the Departments of Radiology (J.M.H., G.P.F., A.C.P., R.G.P, A.K.H.)
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  • Fig 1.
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    Fig 1.

    Graphic representation of mean image noise for the pons, globe, masseter, and air within the maxillary sinus for each of the tested CT series: soft-tissue algorithm, filtered back-projection, low dose; bone algorithm, filtered back-projection, low dose; Veo model-based iterative reconstruction, low dose; soft-tissue algorithm, filtered back-projection, standard dose; and bone algorithm, filtered back-projection, standard dose.

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    Fig 2.

    Graphic representation of mean image quality for the brain, cribriform plate, globe, inferior rectus muscle, lamina papyracea, middle turbinate, nasal septum, and optic nerve for each of the tested CT series: soft-tissue algorithm, filtered back-projection, low dose; bone algorithm, filtered back-projection, low dose; Veo model-based iterative reconstruction, low dose; soft-tissue algorithm, filtered back-projection, standard dose; and bone algorithm, filtered back-projection, standard dose.

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    Fig 3.

    Axial noncontrast sinus CT (window level, 40 HU; window width, 400 HU) through the level of the orbits for the following imaging series: soft-tissue algorithm, filtered back-projection, standard dose (A); bone algorithm, filtered back-projection, standard dose (B); soft-tissue algorithm, filtered back-projection, low dose (C); bone algorithm, filtered back-projection, low dose (D); and Veo model-based iterative reconstruction, low dose (E). The decreased image noise secondary to Veo allows improved visualization of orbital and intracranial soft-tissue structures relative to the other low-dose protocols but not to the level of the standard-dose sinus CT.

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    Fig 4.

    Coronal noncontrast sinus CT (window level, 800 HU; window width, 3500 HU) through the level of the maxillary sinuses for the following imaging series: soft-tissue algorithm, filtered back-projection, standard dose (A); bone algorithm, filtered back-projection, standard dose (B); soft-tissue algorithm, filtered back-projection, low dose (C); bone algorithm, filtered back-projection, low dose (D); and Veo model-based iterative reconstruction, low dose (E). The noise reduction achieved with Veo results in loss of edge enhancement, making thin bones such as the nasal septum (white arrow) and left lamina papyracea (white arrowhead) difficult to see.

Tables

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    Table 1:

    Image-noise measurementa

    Pons (n = 20)Globe (n = 20)Masseter (n = 20)Maxillary Sinus (n = 20)Total (n = 80)
    SOFT FBP LD74.9 (10.60)b55.6 (8.79)b52.6 (8.79)b45.3 (13.16)b57.1 (15.06)b
    BONE FBP LD278.8 (36.73)b173.0 (19.66)b175.3 (27.03)b105.5 (15.64)b183.1 (67.38)b
    VEO LD18.9 (2.98)12.4 (1.37)14.3 (2.16)12.3 (2.11)14.5 (3.49)
    SOFT FBP SD24.7 (5.14)b19.5 (3.06)b19.1 (3.35)b17.5 (2.48)b20.2 (4.48)b
    BONE FBP SD97.4 (14.47)b66.9 (7.78)b66.3 (8.96)b50.1 (6.42)b70.2 (19.73)b
    • ↵a Values are expressed as mean (SD) of image noise measured in Hounsfield units.

    • ↵b Statistically significant difference (P < .001) in paired comparison with VEO LD.

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    Table 2:

    Image-quality assessmenta

    Brain (n = 40)Globe (n = 40)Inferior Rectus Muscle (n = 40)Optic Nerve (n = 40)Cribriform Plate (n = 40)Lamina Papyracea (n = 40)Middle Turbinate (n = 40)Nasal Septum (n = 40)Total (n = 320)
    SOFT FBP LD1.5 (0.51)b1.6 (0.55)b1.9 (0.43)b1.8 (0.52)b3.3 (0.47)3.1 (0.38)b3.3 (0.44)3.1 (0.38)2.4 (0.90)b
    BONE FBP LD1.0 (0.00)b1.0 (0.16)b1.0 (0.16)b1.1 (0.27)b3.7 (0.62)b3.7 (0.56)b3.4 (0.58)3.6 (0.59)b2.3 (1.35)b
    VEO LD2.8 (0.41)2.9 (0.35)3.1 (0.32)3.1 (0.32)3.2 (0.48)2.7 (0.53)3.2 (0.53)3.0 (0.45)3.0 (0.46)
    SOFT FBP SD3.4 (0.55)b4.0 (0.42)b4.0 (0.58)b4.1 (0.40)b4.0 (0.51)b3.9 (0.47)b4.0 (0.55)b3.9 (0.56)b3.9 (0.54)b
    BONE FBP SD2.0 (0.28)b2.5 (0.51)b3.0 (0.53)3.1 (0.45)4.7 (0.47)b4.9 (0.33)b4.7 (0.46)b4.9 (0.36)b3.7 (1.19)b
    • ↵a Values are expressed as mean (SD). Image-quality scale ranges from 1 (unacceptable noise, nondiagnostic) to 5 (excellent image quality, best diagnostic value).

    • ↵b Statistically significant difference (P < .001) in paired comparison with VEO LD.

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American Journal of Neuroradiology: 35 (4)
American Journal of Neuroradiology
Vol. 35, Issue 4
1 Apr 2014
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J.M. Hoxworth, D. Lal, G.P. Fletcher, A.C. Patel, M. He, R.G. Paden, A.K. Hara
Radiation Dose Reduction in Paranasal Sinus CT Using Model-Based Iterative Reconstruction
American Journal of Neuroradiology Apr 2014, 35 (4) 644-649; DOI: 10.3174/ajnr.A3749

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Radiation Dose Reduction in Paranasal Sinus CT Using Model-Based Iterative Reconstruction
J.M. Hoxworth, D. Lal, G.P. Fletcher, A.C. Patel, M. He, R.G. Paden, A.K. Hara
American Journal of Neuroradiology Apr 2014, 35 (4) 644-649; DOI: 10.3174/ajnr.A3749
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