Abstract
SUMMARY: Resting-state fMRI measures spontaneous low-frequency fluctuations in the BOLD signal to investigate the functional architecture of the brain. Application of this technique has allowed the identification of various RSNs, or spatially distinct areas of the brain that demonstrate synchronous BOLD fluctuations at rest. Various methods exist for analyzing resting-state data, including seed-based approaches, independent component analysis, graph methods, clustering algorithms, neural networks, and pattern classifiers. Clinical applications of resting-state fMRI are at an early stage of development. However, its use in presurgical planning for patients with brain tumor and epilepsy demonstrates early promise, and the technique may have a future role in providing diagnostic and prognostic information for neurologic and psychiatric diseases.
ABBREVIATIONS:
- BOLD
- blood oxygen level–dependent
- DMN
- default mode network
- ICA
- independent component analysis
- RS-fMRI
- resting-state fMRI
- RSN
- resting-state network
- © 2013 by American Journal of Neuroradiology
Indicates open access to non-subscribers at www.ajnr.org
Jump to section
Related Articles
Cited By...
- Estimating Brain Similarity Networks with Diffusion MRI
- Multimodal MRI Marker of Cognition Explains the Association Between Cognition and Mental Health in UK Biobank
- Functional Connectivity Alterations in Spinocerebellar Ataxia Type 10: Insights from Gray Matter Atrophy
- State-dependent relationship between lower and higher order networks in fMRI brain dynamics
- Co-Activation Patterns in Neonates using High-Density Diffuse Optical Tomography: Insights into Early Dynamic Functional Connectivity
- The Link to Oxidative Metabolism Varies across rs-fMRI Metrics: A Whole-Brain Assessment Using Macrovascular Correction
- Evidence for white matter intrinsic connectivity networks at rest and during a task: a large-scale study and templates
- Probabilistic Presurgical Language fMRI Atlas of Patients with Brain Tumors
- Subcortical Hubs of Brain Networks Sustaining Human Consciousness
- Neurocognitive and resting-state functional MRI changes in patients with diffuse gliomas after chemoradiotherapy
- Behavior- and circuit-specific cortico-striatal decoupling during the early development of Parkinsons disease-like syndrome
- Static and Dynamic Cross-Network Functional Connectivity Shows Elevated Entropy in Schizophrenia Patients
- Inter-modality source coupling: a fully-automated whole-brain data-driven structure-function fingerprint shows replicable links to reading in a large-scale (N~8K) analysis
- Mitigation of Fetal Irradiation Injury from Mid-Gestation Total Body Radiation with Mitochondrial-Targeted GS-Nitroxide JP4-039
- TR(acking) individuals down: exploring the effect of temporal resolution in resting-state functional MRI fingerprinting
- Resting-state functional connectivity in children cooled for neonatal encephalopathy
- How can graph theory inform the dual-stream model of speech processing? a resting-state fMRI study of post-stroke aphasia
- Atlasing white matter and grey matter joint contributions to resting-state networks in the human brain
- Subcortical Functional Connectivity Gradients in Temporal Lobe Epilepsy
- Individualized fMRI connectivity defines signatures of antidepressant and placebo responses in major depression
- Acute tryptophan depletion balances altered resting-state functional connectivity of the salience network in female patients recovered from anorexia nervosa
- Task-based fMRI in early Multiple Sclerosis: what is the best head motion correction approach?
- Heart-brain connections: phenotypic and genetic insights from 40,000 cardiac and brain magnetic resonance images
- Functional connectome of brainstem nuclei involved in autonomic, limbic, pain and sensory processing in living humans from 7 Tesla resting state fMRI
- Functional connectome of arousal and motor brainstem nuclei in living humans by 7 Tesla resting-state fMRI
- Automated skull stripping in mouse fMRI analysis using 3D U-Net
- A systematic data-driven approach to analyze sensor-level EEG connectivity: Identifying robust phase-synchronized network components using surface Laplacian with spectral-spatial PCA
- Genetic influences on the intrinsic and extrinsic functional organizations of the cerebral cortex
- The "neural shift" of sleep quality and cognitive ageing: A resting-state MEG study of transient neural dynamics
- Individualized Spatial Network Predictions Using Siamese Convolutional Neural Networks: A Resting-State fMRI Study of over 11,000 Unaffected Individuals
- Post-stroke reorganization of transient brain activity characterizes deficits and recovery of cognitive functions
- Evolutionary optimization in classification of early-MCI patients from healthy controls using graph measures of resting-state fMRI
- Optimizing EEG source reconstruction with concurrent fMRI-derived spatial priors
- How to Interpret Resting-State fMRI: Ask Your Participants
- Hierarchical modelling of functional brain networks in population and individuals from big fMRI data
- Lasting effects of a single psilocybin dose on resting-state functional connectivity in healthy individuals
- Evolving Use of fMRI in Medicare Beneficiaries
- Phase-locking of resting-state brain networks with the gastric basal electrical rhythm
- Early alterations of large-scale brain networks temporal dynamics in young children with autism
- Common variants contribute to intrinsic human brain functional networks
- Integrity of Neurocognitive Networks in Dementing Disorders as Measured with Simultaneous PET/Functional MRI
- Greater TMS-evoked frontoparietal effective connectivity is correlated with better cognitive performance
- JuSpace: A tool for spatial correlation analyses of magnetic resonance imaging data with nuclear imaging derived neurotransmitter maps
- Excitatory-Inhibitory Balance within EEG Microstates and Resting-state fMRI Networks: Assessed via Simultaneous PET-MR-EEG Imaging
- Transient resting-state network dynamics in cognitive ageing
- Topological Data Analysis Reveals Robust Alterations in the Whole-Brain and Frontal Lobe Functional Connectomes in Attention-Deficit/Hyperactivity Disorder
- Measuring robust functional connectivity from resting-state MEG using amplitude and entropy correlation across frequency-bands and temporal scales
- Typicality of Functional Connectivity robustly captures motion artifacts in rs-fMRI across datasets, atlases and preprocessing pipelines
- Theoretical properties of nearest-neighbor distance distributions and novel metrics for high dimensional bioinformatics data
- An open database of resting-state fMRI in awake rats
- Topological Data Analysis reveals robust alterations in the whole-brain and frontal lobe functional connectomes in Attention-Deficit/Hyperactivity Disorder
- Resting state functional connectivity in early post-anesthesia recovery is characterized by globally reduced anticorrelations
- Spatial dynamics within and between brain functional domains: A hierarchical approach to study time-varying brain function
- Dynamic up- and down-regulation of the default (DMN) and extrinsic (EMN) mode networks during alternating task-on and task-off periods
- The Importance of Anti-Correlations in Graph Theory Based Classification of Autism Spectrum Disorder
- Effects of childhood maltreatment on social cognition and brain functional connectivity in borderline personality disorder patients
- Test-Retest Reliability of Task-based and Resting-state Blood Oxygen Level Dependence and Cerebral Blood Flow measures
- Resting-State Brain Fluctuation and Functional Connectivity Dissociate Moral Injury from Posttraumatic Stress Disorder
- Atypical flexibility in dynamic functional connectivity quantifies the severity in autism spectrum disorder
- Fundamental Differences: A Basis Set for Characterizing Inter-Individual Variation in Resting State Connectomes
- Resting state cerebral networks in mouse lemur primates: from multilevel validation to comparison with humans
- Multiple spin echos in cerebral dynamics: Evidence for spontaneous symmetry breaking during pulsation
- A new analysis of resting state connectivity and graph theory reveals distinctive short-term modulations due to whisker stimulation in rats
- Default Mode Network in Temporal Lobe epilepsy: interactions with memory performance
- Interaction of Developmental Venous Anomalies with Resting-State Functional MRI Measures
- Resting-State Functional MRI: Everything That Nonexperts Have Always Wanted to Know
- Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET
- Resting-State Networks as Simultaneously Measured with Functional MRI and PET
- Resting-State Seed-Based Analysis: An Alternative to Task-Based Language fMRI and Its Laterality Index
- Abnormal Amygdala Resting-State Functional Connectivity in Irritable Bowel Syndrome
- Presurgical Assessment of the Sensorimotor Cortex Using Resting-State fMRI
- Influence of Resting-State Network on Lateralization of Functional Connectivity in Mesial Temporal Lobe Epilepsy
- Structural and Resting-State Brain Connectivity of Motor Networks After Stroke
- Multivariate Classification of Blood Oxygen Level-Dependent fMRI Data with Diagnostic Intention: A Clinical Perspective