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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleFunctional
Open Access

Stability in Brain Glucose Metabolism Following Brown Adipose Tissue Inactivation in Chinese Adults

Q. Miao, X.L. Zhao, Q.Y. Zhang, Z.Y. Zhang, Y.H. Guan, H.Y. Ye, S. Zhang, M.F. Zeng, C.T. Zuo and Y.M. Li
American Journal of Neuroradiology September 2012, 33 (8) 1464-1469; DOI: https://doi.org/10.3174/ajnr.A3006
Q. Miao
aFrom the Division of Endocrinology and Metabolism (Q.M., X.L.Z., Q.Y.Z., Z.Y.Z., H.Y.Y., S.Z., M.F.Z., Y.M.L.)
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X.L. Zhao
aFrom the Division of Endocrinology and Metabolism (Q.M., X.L.Z., Q.Y.Z., Z.Y.Z., H.Y.Y., S.Z., M.F.Z., Y.M.L.)
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Q.Y. Zhang
aFrom the Division of Endocrinology and Metabolism (Q.M., X.L.Z., Q.Y.Z., Z.Y.Z., H.Y.Y., S.Z., M.F.Z., Y.M.L.)
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Z.Y. Zhang
aFrom the Division of Endocrinology and Metabolism (Q.M., X.L.Z., Q.Y.Z., Z.Y.Z., H.Y.Y., S.Z., M.F.Z., Y.M.L.)
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Y.H. Guan
bDepartment of Internal Medicine, and PET Center (Y.H.G.. C.T.Z.), Division of Nuclear Medicine, Department of Radiology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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H.Y. Ye
aFrom the Division of Endocrinology and Metabolism (Q.M., X.L.Z., Q.Y.Z., Z.Y.Z., H.Y.Y., S.Z., M.F.Z., Y.M.L.)
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S. Zhang
aFrom the Division of Endocrinology and Metabolism (Q.M., X.L.Z., Q.Y.Z., Z.Y.Z., H.Y.Y., S.Z., M.F.Z., Y.M.L.)
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M.F. Zeng
aFrom the Division of Endocrinology and Metabolism (Q.M., X.L.Z., Q.Y.Z., Z.Y.Z., H.Y.Y., S.Z., M.F.Z., Y.M.L.)
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C.T. Zuo
bDepartment of Internal Medicine, and PET Center (Y.H.G.. C.T.Z.), Division of Nuclear Medicine, Department of Radiology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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Y.M. Li
aFrom the Division of Endocrinology and Metabolism (Q.M., X.L.Z., Q.Y.Z., Z.Y.Z., H.Y.Y., S.Z., M.F.Z., Y.M.L.)
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Data supplements

  • Supplemental Online Tables and Figure

    Files in this Data Supplement:

    • Online Tables 1-5 and Figure (PDF) -

      Online Table 1: Demographic features of subjects with activated BAT and controls

      Online Table 2: Demographic features of BAT-positive subjects

      Online Table 3: Brain regions with significant metabolic difference between BAT-positive and BAT-negative groups

      Online Table 4: Brain regions with significant metabolic changes following BAT elimination by heat exposure (28°C)

      Online Table 5: Group differences in regional cerebral metabolism after heat exposure of the BAT-positive group (28°C)

      Online Figure: BAT activity as assessed with 18F-FDG. The intense yellow regions in the transverse plane of the PET/CT image (A) show the areas of BAT (arrow). Comparative PET-CT scans reveal the patterns of 18F-FDG uptake in the same subject under thermoneutral conditions (22°C) and after exposure to heat (28°C). There is no detectable BAT activity after heat exposure (arrow, B).
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American Journal of Neuroradiology: 33 (8)
American Journal of Neuroradiology
Vol. 33, Issue 8
1 Sep 2012
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Cite this article
Q. Miao, X.L. Zhao, Q.Y. Zhang, Z.Y. Zhang, Y.H. Guan, H.Y. Ye, S. Zhang, M.F. Zeng, C.T. Zuo, Y.M. Li
Stability in Brain Glucose Metabolism Following Brown Adipose Tissue Inactivation in Chinese Adults
American Journal of Neuroradiology Sep 2012, 33 (8) 1464-1469; DOI: 10.3174/ajnr.A3006

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Stability in Brain Glucose Metabolism Following Brown Adipose Tissue Inactivation in Chinese Adults
Q. Miao, X.L. Zhao, Q.Y. Zhang, Z.Y. Zhang, Y.H. Guan, H.Y. Ye, S. Zhang, M.F. Zeng, C.T. Zuo, Y.M. Li
American Journal of Neuroradiology Sep 2012, 33 (8) 1464-1469; DOI: 10.3174/ajnr.A3006
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Cold-induced activity of brown adipose tissue in young lean men of South-Asian and European origin
    W. M. Admiraal, H. J. Verberne, F. A. Karamat, M. R. Soeters, J. B. L. Hoekstra, F. Holleman
    Diabetologia 2013 56 10
  • Brown Adipose Tissue Function is Accompanied by Cerebral Activation in Lean But Not in Obese Humans
    Janne Orava, Lauri Nummenmaa, Tommi Noponen, Tapio Viljanen, Riitta Parkkola, Pirjo Nuutila, Kirsi A Virtanen
    Journal of Cerebral Blood Flow & Metabolism 2014 34 6
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  • Gender differences in brown adipose tissue-related brain functional networks: an 18F-FDG-PET study
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  • Neuropeptide Y Plays an Important Role in the Relationship Between Brain Glucose Metabolism and Brown Adipose Tissue Activity in Healthy Adults: A PET/CT Study
    Qiongyue Zhang, Qing Miao, Yehong Yang, Jiaying Lu, Huiwei Zhang, Yonghao Feng, Wei Wu, Xiaoming Zhu, Boni Xiang, Quanya Sun, Yihui Guan, Yiming Li, Chuantao Zuo, Hongying Ye
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