Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleInterventional

Endovascular Therapy of 500 Small Asymptomatic Unruptured Intracranial Aneurysms

H. Oishi, M. Yamamoto, T. Shimizu, K. Yoshida and H. Arai
American Journal of Neuroradiology May 2012, 33 (5) 958-964; DOI: https://doi.org/10.3174/ajnr.A2858
H. Oishi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Yamamoto
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
T. Shimizu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
K. Yoshida
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H. Arai
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Tables

    • View popup
    Table 1:

    Characteristics of patients and aneurysms

    CharacteristicsData%
    No. of patients457
    Women333(72.9)
    No. of aneurysms500
    No. of patients with multiple aneurysms endovascularly treated36(7.9)
    Age (yr)
        Mean59.9 ± 10.5
        Median61.0
        Range19–89
    Aneurysm detection
        Radiologic examinations for various reasons unrelated to aneurysms465(93.0)
        Associated with ruptured aneurysms35(7)
    • View popup
    Table 2:

    Aneurysm locations

    LocationNo.%
    Anterior circulation449(89.8)
        Cavernous segment of ICA11(2.2)
        Siphon of ICA126(25.2)
        PcomA76(15.2)
        AChoA19(3.8)
        ICA bifurcation13(2.6)
        AcomA97(19.4)
        ACA26(5.2)
        MCA81(16.2)
    Posterior circulation51(10.2)
        BA bifurcation34(6.8)
        SCA8(1.6)
        PICA4(0.8)
        PCA4(0.8)
        BA trunk1(0.2)
    • Note:—PCA indicates posterior cerebral artery; SCA, superior cerebellar artery.

    • View popup
    Table 3:

    Aneurysm characteristics

    Characteristics
    Aneurysm size (mm) (mean) (range)5.1 ± 1.72.0–9.5
        <5223(44.6%)
        ≥5277(55.4%)
    Aneurysm neck (mm) (mean) (range)3.1 ± 1.11.0–6.5
        <4378(75.6%)
        ≥4122(22.4%)
    D/N ratio1.74 ± 0.480.71–4.0
        <1.5146(29.2%)
        ≥1.5354(70.8%)
    • View popup
    Table 4:

    Characteristics of 19 aneurysms with technically failed treatment

    Location
    MCA9/81(11.1%)
    AcomA4/97(4.1%)
    PcomA2/76(2.6%)
    ACA2/26(7.7%)
    AChoA1/19(5.3%)
    ICA bifurcation1/13(7.7%)
    Aneurysm size (mm)
        <512/223(5.4%)
        ≥57/277(2.5%)
    D/N ratio
        <1.512/146(8.2%)
        ≥1.57/354(2.0%)
    • View popup
    Table 5:

    Immediate angiographic outcomes according to aneurysm characteristics

    Outcome%
    Overall(n = 481)
        CO309(64.2)
        RN72(15.0)
        RA100(20.8)
    Aneurysms measuring <5 mm(n = 211)
        CO134(63.5)
        RN24(11.4)
        RA53(25.1)
    Aneurysms measuring ≥5 mm(n = 270)
        CO175(64.8)
        RN48(17.8)
        RA47(17.4)
    D/N ratio <1.5(n = 134)
        CO68(50.7)
        RN15(11.2)
        RA51(38.1)
    D/N ratio ≥1.5(n = 347)
        CO241(69.5)
        RN57(16.4)
        RA49(14.1)
    • View popup
    Table 6:

    Immediate angiographic outcomes according to endovascular techniques

    Technique/Outcome%
    Simple(n = 190)
        CO126(66.3)
        RN24(12.6)
        RA40(21.1)
    Balloon-assisted(n = 247)
        CO166(67.2)
        RN40(16.2)
        RA41(16.6)
    Double-catheter(n = 44)
        CO17(38.6)
        RN8(18.2)
        RA19(43.2)
    • View popup
    Table 7:

    Immediate and final anatomic outcomes according to the types of coils used

    OutcomeBare Coil (n = 339)Biologically Modified Coils (n = 88)
    No.%No.%
    Immediate
        CO225(66.4)49(55.7)
        RN49(14.5)19(21.6)
        RA65(19.2)20(22.7)
    Final
        CO233(68.7)61(69.3)
        RN50(14.7)17(19.3)
        RA56(16.5)10(11.4)
    • View popup
    Table 8:

    Anatomic follow-up outcomes according to aneurysm characteristics

    CharacteristicsUnchangedMinor RecurrenceMajor RecurrenceImproved
    No.%No.%No.%No.%
    Overall (N = 427)272(63.7)29(6.8)43(10.1)83(19.4)
    Aneurysms measuring <5 mm (n = 187)123(65.8)7(3.7)9(4.8)48(25.7)
    Aneurysms measuring ≥5 mm (n = 240)149(62.1)22(9.2)34(14.2)35(14.6)
    D/N ratio <1.5 (n = 117)56(47.9)10(8.5)18(15.4)33(28.2)
    D/N ratio ≥1.5 (n = 310)216(69.7)19(6.1)25(8.1)50(16.1)
    • View popup
    Table 9:

    Anatomic follow-up outcomes according to endovascular techniques

    TechniqueUnchangedMinor RecurrenceMajor RecurrenceImproved
    No.%No.%No.%No.%
    Simple (n = 168)121(72.0)6(3.6)13(7.7)28(16.7)
    Balloon-assisted (n = 222)139(62.6)19(8.6)21(9.5)43(19.4)
    Double-catheter (n = 37)12(32.4)4(10.8)9(24.3)12(32.4)
    • View popup
    Table 10:

    Ischemic and hemorrhagic complications according to aneurysm characteristics and endovascular techniques

    Characteristic/TechniqueIschemicHemorrhagic
    No.%No.%
    Aneurysms measuring <5 mm8/223(3.6)5/223(2.2)
    Aneurysms measuring ≥5 mm11/277(4.0)6/277(2.2)
    D/N ratio <1.510/146(6.8)4/146(2.7)
    D/N ratio ≥1.59/354(2.5)7/354(2.0)
    Simple7/190(3.7)4/190(2.1)
    Balloon-assisted10/247(4.0)5/247(2.0)
    Double-catheter2/44(4.5)1/44(2.3)
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 33 (5)
American Journal of Neuroradiology
Vol. 33, Issue 5
1 May 2012
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Endovascular Therapy of 500 Small Asymptomatic Unruptured Intracranial Aneurysms
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
H. Oishi, M. Yamamoto, T. Shimizu, K. Yoshida, H. Arai
Endovascular Therapy of 500 Small Asymptomatic Unruptured Intracranial Aneurysms
American Journal of Neuroradiology May 2012, 33 (5) 958-964; DOI: 10.3174/ajnr.A2858

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Endovascular Therapy of 500 Small Asymptomatic Unruptured Intracranial Aneurysms
H. Oishi, M. Yamamoto, T. Shimizu, K. Yoshida, H. Arai
American Journal of Neuroradiology May 2012, 33 (5) 958-964; DOI: 10.3174/ajnr.A2858
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Evaluation of effectiveness and safety of the CorPath GRX robotic system in endovascular embolization procedures of cerebral aneurysms
  • Long-Term Rupture Risk in Patients with Unruptured Intracranial Aneurysms Treated with Endovascular Therapy: A Systematic Review and Meta-Analysis
  • Long-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral Aneurysms
  • Risk factors for and outcomes of intraprocedural rupture during endovascular treatment of unruptured intracranial aneurysms
  • Endovascular treatment of intracranial aneurysms with the LVIS device: a systematic review
  • Current Trends and Results of Endovascular Treatment of Unruptured Intracranial Aneurysms at a Single Institution in the Flow-Diverter Era
  • Aneurysmal subarachnoid hemorrhage: a statewide assessment of outcome based on risk factors, aneurysm characteristics, and geo-demography
  • Treatment results of endosaccular coil embolization of asymptomatic unruptured intracranial aneurysms in elderly patients
  • Conventional endovascular treatment of small intracranial aneurysms is not associated with additional risks compared with treatment of larger aneurysms
  • Endovascular Therapy for Asymptomatic Unruptured Intracranial Aneurysms: JR-NET and JR-NET2 Findings
  • When Dealing with Unruptured Aneurysms, What Do Low Morbidity and Mortality Mean?
  • Crossref (53)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Procedural Clinical Complications, Case-Fatality Risks, and Risk Factors in Endovascular and Neurosurgical Treatment of Unruptured Intracranial Aneurysms
    Annemijn M. Algra, Antti Lindgren, Mervyn D. I. Vergouwen, Jacoba P. Greving, Irene C. van der Schaaf, Tristan P. C. van Doormaal, Gabriel J. E. Rinkel
    JAMA Neurology 2019 76 3
  • Complications of endovascular treatment for intracranial aneurysms: Management and prevention
    Yon Kwon Ihn, Shang Hun Shin, Seung Kug Baik, In Sup Choi
    Interventional Neuroradiology 2018 24 3
  • Endovascular treatment of intracranial aneurysms with the LVIS device: a systematic review
    Xiaoguang Zhang, Junjie Zhong, Heng Gao, Feng Xu, Nicholas C Bambakidis
    Journal of NeuroInterventional Surgery 2017 9 6
  • Endovascular Therapy for Asymptomatic Unruptured Intracranial Aneurysms
    Tomoyoshi Shigematsu, Toshiyuki Fujinaka, Toshiki Yoshimine, Hirotoshi Imamura, Akira Ishii, Chiaki Sakai, Nobuyuki Sakai
    Stroke 2013 44 10
  • Current Trends and Results of Endovascular Treatment of Unruptured Intracranial Aneurysms at a Single Institution in the Flow-Diverter Era
    O. Petr, W. Brinjikji, H. Cloft, D.F. Kallmes, G. Lanzino
    American Journal of Neuroradiology 2016 37 6
  • Intraprocedural Rupture During Endovascular Treatment of Intracranial Aneurysm: Clinical Results and Literature Review
    Yung Ki Park, Hyeong-Joong Yi, Kyu-Sun Choi, Young-Jun Lee, Hyoung-Joon Chun
    World Neurosurgery 2018 114
  • Safety of stent-assisted coiling for the treatment of wide-necked ruptured aneurysm: A systematic literature review and meta-analysis of prevalence
    Shadi Bsat, Ayman Bsat, Hani Tamim, Hani Chanbour, Safwan Omar Alomari, Mohamad Nabih El Houshiemy, Charbel Moussalem, Ibrahim Omeis
    Interventional Neuroradiology 2020 26 5
  • Risk factors for and outcomes of intraprocedural rupture during endovascular treatment of unruptured intracranial aneurysms
    Shuhei Kawabata, Hirotoshi Imamura, Hidemitsu Adachi, Shoichi Tani, So Tokunaga, Takayuki Funatsu, Keita Suzuki, Nobuyuki Sakai
    Journal of NeuroInterventional Surgery 2018 10 4
  • Evaluation of effectiveness and safety of the CorPath GRX robotic system in endovascular embolization procedures of cerebral aneurysms
    Vitor Mendes Pereira, Hal Rice, Laetitia De Villiers, Nader Sourour, Frédéric Clarencon, Julian Spears, Alejandro Tomasello, David Hernandez, Nicole M Cancelliere, Xiao Yu Eileen Liu, Patrick Nicholson, Vincent Costalat, Gregory Gascou, Pasquale Mordasini, Jan Gralla, Mario Martínez-Galdámez, Jorge Galvan Fernandez, Monika Killer-Oberpfalzer, David S Liebeskind, Raymond D Turner, Raphael Blanc, Michel Piotin
    Journal of NeuroInterventional Surgery 2024 16 4
  • Risk factors for angiographic recurrence after treatment of unruptured intracranial aneurysms: Outcomes from a series of 178 unruptured aneurysms treated by regular coiling or surgery
    Anne-Laure Bernat, Frédéric Clarençon, Arthur André, Aurélien Nouet, Stéphane Clémenceau, Nader-Antoine Sourour, Federico Di Maria, Vincent Degos, Jean-Louis Golmard, Philippe Cornu, Anne-Laure Boch
    Journal of Neuroradiology 2017 44 5

More in this TOC Section

  • CT-Guided C2 Dorsal Root Ganglion Radiofrequency Ablation for the Treatment of Cervicogenic Headache: Case Series and Clinical Outcomes
  • Safety, Efficacy, and Durability of Stent-Assisted Coiling Treatment of M2 (Insular) Segment MCA Aneurysms
  • Endovascular Management of Intracranial Dural AVFs: Transvenous Approach
Show more INTERVENTIONAL

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire