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Research ArticleHead and Neck Imaging

Dampening of Blood-Flow Pulsatility along the Carotid Siphon: Does Form Follow Function?

T. Schubert, F. Santini, A.F. Stalder, J. Bock, S. Meckel, L. Bonati, M. Markl and S. Wetzel
American Journal of Neuroradiology June 2011, 32 (6) 1107-1112; DOI: https://doi.org/10.3174/ajnr.A2426
T. Schubert
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F. Santini
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A.F. Stalder
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J. Bock
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S. Meckel
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L. Bonati
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M. Markl
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S. Wetzel
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    Fig 1.

    Placement of 2D planes for flow measurement at the C4 and C7 segments in subjects with helical (A) and laminar (B) carotid blood flow patterns.

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    Fig 2.

    Velocity diagrams at the C4 (left) and C7 (right) segments of 1 individual carotid artery with peak acceleration values of 74 mL/s2 at C4 and 34 mL/s2 at C7.

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    Fig 3.

    PI (top), RI (middle), and PA (bottom) of the 17 volunteers proximally (at segment C4) and distally (segment C7) averaged over the left and right ICAs.

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    Fig 4.

    Time-resolved blood flow visualization in a subject with helical blood flow in the left ICA.

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    Table 1:

    Estimates and results of the likelihood ratio tests for the fixed effects of the linear mixed-effects model

    End PointContrastEstimateχ2 (1)P Value
    PIDistal-proximal−0.1937.8<.0001
    RIDistal-proximal−0.0827.5<.0001
    PADistal-proximal−0.0331.2<.0001
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    Table 2:

    Mean values and the standard error of PI, RI, and PA proximal (C4) and distal (C7) to the carotid siphona

    End PointLocationMean ValueStandard Error
    PIProximal (C4),1.05680.02425
    distal (C7)0.86660.02576
    RIProximal (C4),0.50390.01204
    distal (C7)0.42990.01409
    PAProximal (C4),0.08460.00375
    distal (C7)0.05810.00364
    • a The standard error is defined as the SD of the sampling distribution associated with the estimation method.

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American Journal of Neuroradiology: 32 (6)
American Journal of Neuroradiology
Vol. 32, Issue 6
1 Jun 2011
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Cite this article
T. Schubert, F. Santini, A.F. Stalder, J. Bock, S. Meckel, L. Bonati, M. Markl, S. Wetzel
Dampening of Blood-Flow Pulsatility along the Carotid Siphon: Does Form Follow Function?
American Journal of Neuroradiology Jun 2011, 32 (6) 1107-1112; DOI: 10.3174/ajnr.A2426

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Dampening of Blood-Flow Pulsatility along the Carotid Siphon: Does Form Follow Function?
T. Schubert, F. Santini, A.F. Stalder, J. Bock, S. Meckel, L. Bonati, M. Markl, S. Wetzel
American Journal of Neuroradiology Jun 2011, 32 (6) 1107-1112; DOI: 10.3174/ajnr.A2426
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