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Research ArticleBrain

Differentiation of Typical and Atypical Parkinson Syndromes by Quantitative MR Imaging

N.K. Focke, G. Helms, P.M. Pantel, S. Scheewe, M. Knauth, C.G. Bachmann, J. Ebentheuer, P. Dechent, W. Paulus and C. Trenkwalder
American Journal of Neuroradiology December 2011, 32 (11) 2087-2092; DOI: https://doi.org/10.3174/ajnr.A2865
N.K. Focke
aFrom the Department of Clinical Neurophysiology (N.K.F., P.M.P., S.S., C.G.B., W.P.)
dParacelsus Elena Klinik (N.K.F., J.E., C.T.), Specialized Movement Disorders Hospital, Kassel, Germany.
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G. Helms
bMR-Research in Neurology and Psychiatry (G.H., P.D.)
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P.M. Pantel
aFrom the Department of Clinical Neurophysiology (N.K.F., P.M.P., S.S., C.G.B., W.P.)
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S. Scheewe
aFrom the Department of Clinical Neurophysiology (N.K.F., P.M.P., S.S., C.G.B., W.P.)
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M. Knauth
cDepartment of Neuroradiology (M.K.), Georg-August University Göttingen, Göttingen, Germany
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C.G. Bachmann
aFrom the Department of Clinical Neurophysiology (N.K.F., P.M.P., S.S., C.G.B., W.P.)
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J. Ebentheuer
dParacelsus Elena Klinik (N.K.F., J.E., C.T.), Specialized Movement Disorders Hospital, Kassel, Germany.
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P. Dechent
bMR-Research in Neurology and Psychiatry (G.H., P.D.)
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W. Paulus
aFrom the Department of Clinical Neurophysiology (N.K.F., P.M.P., S.S., C.G.B., W.P.)
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C. Trenkwalder
dParacelsus Elena Klinik (N.K.F., J.E., C.T.), Specialized Movement Disorders Hospital, Kassel, Germany.
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Data supplements

  • Supplemental Online Figure and Tables

    Files in this Data Supplement:

    • Online Figure and Tables 1-4 (PDF) -

      Online Figure 1: Substantia nigra region of interest placement. Substantia nigra region of interest overlaid on the 3D-T1 (A) and magnetization transer-map (B). Note the much better visibility of the SN on the magnetization transfer-map.

      Online Table 1: Clinical and demographic details

      Online Table 2: Mean and SD of each region of interest, quantitative map and group

      Online Table 3: Post hoc ANOVA

      Online Table 4: ROC analysis results
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American Journal of Neuroradiology: 32 (11)
American Journal of Neuroradiology
Vol. 32, Issue 11
1 Dec 2011
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Cite this article
N.K. Focke, G. Helms, P.M. Pantel, S. Scheewe, M. Knauth, C.G. Bachmann, J. Ebentheuer, P. Dechent, W. Paulus, C. Trenkwalder
Differentiation of Typical and Atypical Parkinson Syndromes by Quantitative MR Imaging
American Journal of Neuroradiology Dec 2011, 32 (11) 2087-2092; DOI: 10.3174/ajnr.A2865

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Differentiation of Typical and Atypical Parkinson Syndromes by Quantitative MR Imaging
N.K. Focke, G. Helms, P.M. Pantel, S. Scheewe, M. Knauth, C.G. Bachmann, J. Ebentheuer, P. Dechent, W. Paulus, C. Trenkwalder
American Journal of Neuroradiology Dec 2011, 32 (11) 2087-2092; DOI: 10.3174/ajnr.A2865
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  • Combined Diffusion Tensor Imaging and Apparent Transverse Relaxation Rate Differentiate Parkinson Disease and Atypical Parkinsonism
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  • Neurite orientation dispersion and density imaging in the substantia nigra in idiopathic Parkinson disease
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  • Individual Detection of Patients with Parkinson Disease using Support Vector Machine Analysis of Diffusion Tensor Imaging Data: Initial Results
    S. Haller, S. Badoud, D. Nguyen, V. Garibotto, K.O. Lovblad, P.R Burkhard
    American Journal of Neuroradiology 2012 33 11

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