Article Figures & Data
Figures
- Fig 1.
The size of the midsagittal CC for NC and CIS suggestive of MS groups. A, One example of midsagittal CC and its subregions (yellow indicates the genu; red, the body; green, the splenium). B, The midsagittal CC area for the 2 groups. C, The normalized midsagittal CC area by midsagittal brain for the 2 groups.
- Fig 2.
The probability maps for the entire CC and its subregions. A, The entire CC probability map. B, The genu probability map. C, The body probability map. D, The splenium probability map. The gray-scale overlay indicates the probability of a voxel being part of the CC or its subregions.
- Fig 3.
The λ1 and λ23 distributions for the 3 subregions of the CC in CIS suggestive of MS and NCs. A, λ1 (×10−3 mm2/s) distribution for the 3 subregions of the CC for these 2 groups. B, λ23 (×10−3 mm2/s) distribution for the 3 subregions of the CC for these 2 groups.
Tables
Comparison of diffusion indices measured in subregions of CC of NC and CIS
NC (n = 19) CIS (n = 19) Pa Mean ± SD Mean ± SD FA Whole CC 0.46 ± 0.03 0.42 ± 0.04 .001 Genu 0.458 ± 0.038 0.419 ± 0.053 .011 Body 0.442 ± 0.032 0.399 ± 0.046 .002 Splenium 0.494 ± 0.034 0.453 ± 0.062 .020 MDb Whole CC 0.90 ± 0.06 1.02 ± 0.16 .004 Genu 0.868 ± 0.062 0.937 ± 0.142 .064 Body 0.868 ± 0.070 0.995 ± 0.182 .009 Splenium 0.948 ± 0.078 1.087 ± 0.181 .005 λ1c Whole CC 1.38 ± 0.06 1.49 ± 0.15 .010 Genu 1.333 ± 0.059 1.417 ± 0.175 .228 Body 1.310 ± 0.087 1.409 ± 0.177 .024 Splenium 1.505 ± 0.086 1.633 ± 0.197 .016 λ23d Whole CC 0.66 ± 0.07 0.79 ± 0.16 .003 Genu 0.635 ± 0.071 0.718 ± 0.151 .040 Body 0.648 ± 0.070 0.785 ± 0.188 .007 Splenium 0.670 ± 0.082 0.814 ± 0.183 .004 -
a A P value < .01 was considered statistically significant, while a value between .01 and .05 was considered a trend.
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b MD = ×10−3 mm2/s.
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c λ1= ×10−3 mm2/s.
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d λ23 = ×10−3 mm2/s.
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