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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleSpine
Open Access

Application of a Semiautomated Contour Segmentation Tool to Identify the Intervertebral Nucleus Pulposus in MR Images

B.P. Bechara, S.K. Leckie, B.W. Bowman, C.E. Davies, B.I. Woods, E. Kanal, G.A. Sowa and J.D. Kang
American Journal of Neuroradiology October 2010, 31 (9) 1640-1644; DOI: https://doi.org/10.3174/ajnr.A2162
B.P. Bechara
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S.K. Leckie
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B.W. Bowman
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C.E. Davies
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B.I. Woods
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E. Kanal
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G.A. Sowa
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J.D. Kang
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  • Fig 1.
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    Fig 1.

    Midsagittal T2WI of the rabbit lumbar spine with 3 punctured intervertebral disks between the second and third lumbar vertebrae, the third and fourth lumbar vertebrae, and the fourth and fifth lumbar vertebrae, across 3 time points relative to the date of surgery.

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    Fig 2.

    An example of the computer-generated validation image with 0% noise (A) and 40% noise (B). The Gaussian structure is located in the bottom right corner of the image.

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    Fig 3.

    An example of applying the CS method on the lumbar disk between the third and fourth lumbar vertebrae of a control rabbit. After the user selects, with a box, the area surrounding the disk, the contour isolines are generated and the user is prompted to select the largest closed area (shown as a red line) within the vertebrae, which is assumed to represent the NP. After the selection is made, the MR image is displayed with the selected region of interest bounded by a red line. Additionally, the NP boundary between the second and third as well as fourth and fifth lumbar vertebrae is displayed in red.

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    Fig 4.

    The validation dataset SNR of each image is plotted against the area error calculated in equation 3 for both manual and CS of the Gaussian structure. The dotted line is the zero error line, meaning that the segmented area is exactly equal to the area of the structure.

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    Fig 5.

    The time course of the average percentage MR imaging index (A) and average percentage area (B) of the control and punctured rabbit lumbar NPs relative to week 0. Error bars are the standard error at each time point.

Tables

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  • ICCs for manual segmentation and CS

    ICC (area)ICC (MRI index)
    MD1 × MD10.820.95
    MD2 × MD20.730.88
    S × S0.830.92
    CS × CS0.970.99
    MD1 × MD20.850.89
    MD1 × S0.870.96
    MD2 × S0.830.86
    MD1 × CS0.490.53
    MD2 × CS0.640.66
    S × CS0.490.56
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American Journal of Neuroradiology: 31 (9)
American Journal of Neuroradiology
Vol. 31, Issue 9
1 Oct 2010
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Application of a Semiautomated Contour Segmentation Tool to Identify the Intervertebral Nucleus Pulposus in MR Images
B.P. Bechara, S.K. Leckie, B.W. Bowman, C.E. Davies, B.I. Woods, E. Kanal, G.A. Sowa, J.D. Kang
American Journal of Neuroradiology Oct 2010, 31 (9) 1640-1644; DOI: 10.3174/ajnr.A2162
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Cite this article
B.P. Bechara, S.K. Leckie, B.W. Bowman, C.E. Davies, B.I. Woods, E. Kanal, G.A. Sowa, J.D. Kang
Application of a Semiautomated Contour Segmentation Tool to Identify the Intervertebral Nucleus Pulposus in MR Images
American Journal of Neuroradiology Oct 2010, 31 (9) 1640-1644; DOI: 10.3174/ajnr.A2162

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