Article Figures & Data
Figures
- Fig 1.
Axial FLAIR showing outlines of the MR imaging–visible cortical/subcortical tubers, which have been outlined manually to calculate the volume of the cortical/subcortical tubers.
- Fig 2.
Selected ROIs are carefully drawn over the fractional anisotropy color-encoded images, in the genu and splenium of corpus callosum and in the internal capsules.
Tables
- Table 1:
Mean trace, FA, D‖, and D⊥ of the genu and splenium of corpus callosum and internal capsules of patients with TSC and controls
Mean Trace × 10−3 (SD) Mean FA (SD) Mean D‖ × 10−3 (SD) Mean D⊥ × 10−3 (SD) TSC Controls P Value TSC Controls P Value TSC Controls P Value TSC Controls P Value Genu of corpus callosum 3.36 (0.21) 3.03 (0.18) <.01 0.75 (0.06) 0.81 (0.02) <.01 2.34 (0.09) 2.26 (0.17) .33 0.49 (0.12) 0.38 (0.03) <.01 Splenium of corpus callosum 3.18 (0.21) 2.85 (0.18) <.01 0.79 (0.08) 0.85 (0.35) <.01 2.33 (0.17) 2.25 (0.18) .41 0.42 (0.12) 0.30 (0.05) <.01 Internal capsules 2.85 (0.13) 2.73 (0.13) .04 0.69 (0.04) 0.70 (0.03) .95 1.88 (0.11) 1.80 (0.08) .06 0.49 (0.04) 0.46 (0.04) .35 - Table 2:
Pearson correlation coefficient between hemisphere tuber volume and hemispheric tuber number with DTI indices of internal capsules, as well as between total tuber volume and total tuber number with DTI indices of genu and splenium of corpus callosum
Correlation Mean Trace (P Value) Mean FA (P Value) Mean D‖ (P Value) Mean D⊥ (P Value) Left internal capsule Left hemispheric tuber volume r = 0.56 (P = .05) r = 0.36 (P = .25) r = 0.63 (P = .02) r = 0.06 (P = 0.84) Left hemispheric tuber number r = −0.16 (P = .61) r = 0.43 (P = .16) r = 0.13 (P = .68) r = −0.38 (P = .22) Right internal capsule Right hemispheric tuber volume r = 0.67 (P = .02) r = 0.02 (P = .94) r = 0.59 (P = .04) r = 0.23 (P = .46) Right hemispheric tuber number r = 0.04 (P = .89) r = 0.06 (P = .86) r = 0.01 (P = .99) r = −0.06 (P = .84) Genu of corpus callosum Total tuber volume r = 0.77 (P < .01) r = −0.35 (P = .25) r = 0.53 (P = .07) r = 0.43 (P = .16) Total tuber number r = 0.44 (P = .15) r = −0.20 (P = .53) r = −0.23 (P = .47) r = 0.14 (P = .66) Splenium of corpus callosum Total tuber volume r = 0.69 (P = .01) r = −0.60 (P = .04) r = −0.11 (P = .74) r = 0.68 (P = .01) Total tuber number r = 0.19 (P = .55) r = −0.40 (P = .19) r = −0.34 (P = .27) r = 0.40 (P = .19)
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