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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleBrainF

Diagnostic Yield of Double-Dose Gadobutrol in the Detection of Brain Metastasis: Intraindividual Comparison with Double-Dose Gadopentetate Dimeglumine

E.S. Kim, J.H. Chang, H.S. Choi, J. Kim and S.-K. Lee
American Journal of Neuroradiology June 2010, 31 (6) 1055-1058; DOI: https://doi.org/10.3174/ajnr.A2010
E.S. Kim
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J.H. Chang
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H.S. Choi
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J. Kim
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S.-K. Lee
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    Fig 1.

    Comparison of lesion CNR between gadopentetate dimeglumine and gadobutrol. The mean CNR of enhancing lesions is significantly higher with gadobutrol.

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    Fig 2.

    A 63-year-old woman with lung cancer. Gadobutrol MR imaging shows more enhancing lesions than gadopentetate dimeglumine MR imaging (arrow in the right precentral gyrus). Retrospective review of gadopentetate dimeglumine images suggests the existence of a small nodule in the right precentral gyrus, but it is not definite. A thicker enhancing rim and prominent gadolinium spillage are seen on gadobutrol MR imaging (arrowheads).

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    Fig 3.

    A 60-year-old man with lung cancer. Gadobutrol MR imaging shows more enhancing lesions than gadopentetate dimeglumine MR imaging (arrows). There is no suspected lesion on gadopentetate dimegluimine MR imaging. Note the higher signal intensity of the thick enhancing rim (arrowheads). The interval between the 2 MR images is 60 hours.

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American Journal of Neuroradiology: 31 (6)
American Journal of Neuroradiology
Vol. 31, Issue 6
1 Jun 2010
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Diagnostic Yield of Double-Dose Gadobutrol in the Detection of Brain Metastasis: Intraindividual Comparison with Double-Dose Gadopentetate Dimeglumine
E.S. Kim, J.H. Chang, H.S. Choi, J. Kim, S.-K. Lee
American Journal of Neuroradiology Jun 2010, 31 (6) 1055-1058; DOI: 10.3174/ajnr.A2010
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Cited By...

  • Improving Treatment Options for Brain Metastases From ALK-Positive Non-Small-Cell Lung Cancer
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  • Does Higher Gadolinium Concentration Play a Role in the Morphologic Assessment of Brain Tumors? Results of a Multicenter Intraindividual Crossover Comparison of Gadobutrol versus Gadobenate Dimeglumine (the MERIT Study)
  • MR Imaging of Neoplastic Central Nervous System Lesions: Review and Recommendations for Current Practice
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Cite this article
E.S. Kim, J.H. Chang, H.S. Choi, J. Kim, S.-K. Lee
Diagnostic Yield of Double-Dose Gadobutrol in the Detection of Brain Metastasis: Intraindividual Comparison with Double-Dose Gadopentetate Dimeglumine
American Journal of Neuroradiology Jun 2010, 31 (6) 1055-1058; DOI: 10.3174/ajnr.A2010

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