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Research ArticleHead and NeckF

Changes in Perfusion CT of Advanced Squamous Cell Carcinoma of the Head and Neck Treated during the Course of Concomitant Chemoradiotherapy

K. Šurlan-Popovič, S. Bisdas, Z. Rumboldt, T.S. Koh and P. Strojan
American Journal of Neuroradiology March 2010, 31 (3) 570-575; DOI: https://doi.org/10.3174/ajnr.A1859
K. Šurlan-Popovič
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S. Bisdas
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Z. Rumboldt
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T.S. Koh
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P. Strojan
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References

  1. 1.↵
    1. Haddad RI,
    2. Shin DM
    . Recent advances in head and neck cancer. N Engl J Med 2008;359:1143–54
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Pignon JP,
    2. Bourhis J,
    3. Domenge C,
    4. et al
    . Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet 2000;355:949–55
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Bourhis J,
    2. Calais G,
    3. Lapeyre M,
    4. et al
    . Concomitant radiochemotherapy or accelerated radiotherapy: analysis of two randomized trials of the French Head and Neck Cancer Group (GORTEC). Semin Oncol 2004;31:822–26
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Hermans R,
    2. Lambin P,
    3. Van den Bogaert W,
    4. et al
    . Non-invasive tumour perfusion measurement by dynamic CT: preliminary results. Radiother Oncol 1997;44:159–62
    CrossRefPubMed
  5. 5.↵
    1. Bisdas S,
    2. Baghi M,
    3. Smolarz A,
    4. et al
    . Quantitative measurements of perfusion and permeability of oropharyngeal and oral cavity cancer, recurrent disease, and associated lymph nodes using first-pass contrast-enhanced computed tomography studies. Invest Radiol 2007;42:172–79
    CrossRefPubMed
  6. 6.↵
    1. Hermans R,
    2. Meijerink M,
    3. Van den Bogaert W,
    4. et al
    . Tumor perfusion rate determined noninvasively by dynamic computed tomography predicts outcome in head-and-neck cancer after radiotherapy. Int J Radiat Oncol Biol Phys 2003;57:1351–56
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Hoskin PJ,
    2. Saunders MI,
    3. Goodchild K,
    4. et al
    . Dynamic contrast enhanced magnetic resonance scanning as a predictor of response to accelerated radiotherapy for advanced head and neck cancer. Br J Radiol 1999;72:1093–98
    Abstract
  8. 8.↵
    1. Gandhi D,
    2. Chepeha DB,
    3. Miller T,
    4. et al
    . Correlation between initial and early follow-up CT perfusion parameters with endoscopic tumor response in patients with advanced squamous cell carcinomas of the oropharynx treated with organ-preservation therapy. AJNR Am J Neuroradiol 2006;27:101–06
    Abstract/FREE Full Text
  9. 9.↵
    1. Zima A,
    2. Carlos R,
    3. Gandhi D,
    4. et al
    . Can pretreatment CT perfusion predict response of advanced squamous cell carcinoma of the upper aerodigestive tract treated with induction chemotherapy? AJNR Am J Neuroradiol 2007;28:328–34
    Abstract/FREE Full Text
  10. 10.↵
    1. Cao Y,
    2. Popovtzer A,
    3. Li D,
    4. et al
    . Early prediction of outcome in advanced head-and-neck cancer based on tumor blood volume alterations during therapy: a prospective study. Int J Radiat Oncol Biol Phys 2008;72:1287–90
    PubMed
  11. 11.↵
    1. Wiggenraad R,
    2. Mast M,
    3. van Santvoort J,
    4. et al
    . ConPas: a 3-D conformal parotid gland-sparing irradiation technique for bilateral neck treatment as an alternative to IMRT. Strahlenther Onkol 2005;181:673–82
    CrossRefPubMed
  12. 12.↵
    1. Bisdas S,
    2. Nguyen SA,
    3. Anand SK,
    4. et al
    . Outcome prediction after surgery and chemoradiation of squamous cell carcinoma in the oral cavity, oropharynx, and hypopharynx: use of baseline perfusion CT microcirculatory parameters vs. tumor volume. Int J Radiat Oncol Biol Phys 2009;73:1313–18
    PubMed
  13. 13.↵
    1. Billis W,
    2. Fuks Z,
    3. Kolesnick R
    . Signaling in and regulation of ionizing radiation-induced apoptosis in endothelial cells. Recent Prog Horm Res 1998;53:85–92, discussion 93
    PubMed
  14. 14.↵
    1. Cemazar M,
    2. Parkins CS,
    3. Holder AL,
    4. et al
    . Electroporation of human microvascular endothelial cells: evidence for an anti-vascular mechanism of electrochemotherapy. Br J Cancer 2001;84:565–70
    CrossRefPubMed
  15. 15.↵
    1. Clements MK,
    2. Jones CB,
    3. Cumming M,
    4. et al
    . Antiangiogenic potential of camptothecin and topotecan. Cancer Chemother Pharmacol 1999;44:411–16
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Cooper JS,
    2. Fu K,
    3. Marks J,
    4. et al
    . Late effects of radiation therapy in the head and neck region. Int J Radiat Oncol Biol Phys 1995;31:1141–64
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Garcia-Barros M,
    2. Paris F,
    3. Cordon-Cardo C,
    4. et al
    . Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 2003;300:1155–59
    Abstract/FREE Full Text
  18. 18.↵
    1. Ng QS,
    2. Goh V,
    3. Milner J,
    4. et al
    . Acute tumor vascular effects following fractionated radiotherapy in human lung cancer: in vivo whole tumor assessment using volumetric perfusion computed tomography. Int J Radiat Oncol Biol Phys 2007;67:417–24
    PubMed
  19. 19.↵
    1. Ando S,
    2. Nojima K,
    3. Majima H,
    4. et al
    . Evidence for mRNA expression of vascular endothelial growth factor by x-ray irradiation in a lung squamous carcinoma cell line. Cancer Lett 1998;132:75–80
    CrossRefPubMed
  20. 20.↵
    1. Koutsimpelas D,
    2. Brieger J,
    3. Kim DW,
    4. et al
    . Proangiogenic effects of ionizing irradiation on squamous cell carcinoma of the hypopharynx. Auris Nasus Larynx 2008;35:369–75
    CrossRefPubMed
  21. 21.↵
    1. Gupta VK,
    2. Jaskowiak NT,
    3. Beckett MA,
    4. et al
    . Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance. Cancer J 2002;8:47–54
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. Ash L,
    2. Teknos TN,
    3. Gandhi D,
    4. et al
    . Head and neck squamous cell carcinoma: CT perfusion can help noninvasively predict intratumoral microvessel density. Radiology 2009;251:422–28
    CrossRefPubMed
  23. 23.↵
    1. Kamijo T,
    2. Yokose T,
    3. Hasebe T,
    4. et al
    . Potential role of microvessel density in predicting radiosensitivity of T1 and T2 stage laryngeal squamous cell carcinoma treated with radiotherapy. Clin Cancer Res 2000;6:3159–65
    Abstract/FREE Full Text
  24. 24.↵
    1. Bisdas S,
    2. Surlan-Popovic K,
    3. Didanovic V,
    4. et al
    . Functional CT of squamous cell carcinoma in the head and neck: repeatability of tumor and muscle quantitative measurements, inter- and intra-observer agreement. Eur Radiol 2008;18:2241–50
    CrossRefPubMed
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American Journal of Neuroradiology: 31 (3)
American Journal of Neuroradiology
Vol. 31, Issue 3
1 Mar 2010
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Cite this article
K. Šurlan-Popovič, S. Bisdas, Z. Rumboldt, T.S. Koh, P. Strojan
Changes in Perfusion CT of Advanced Squamous Cell Carcinoma of the Head and Neck Treated during the Course of Concomitant Chemoradiotherapy
American Journal of Neuroradiology Mar 2010, 31 (3) 570-575; DOI: 10.3174/ajnr.A1859

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Changes in Perfusion CT of Advanced Squamous Cell Carcinoma of the Head and Neck Treated during the Course of Concomitant Chemoradiotherapy
K. Šurlan-Popovič, S. Bisdas, Z. Rumboldt, T.S. Koh, P. Strojan
American Journal of Neuroradiology Mar 2010, 31 (3) 570-575; DOI: 10.3174/ajnr.A1859
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  • Prediction of Locoregional Control in Head and Neck Squamous Cell Carcinoma with Serial CT Perfusion during Radiotherapy
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    American Journal of Neuroradiology 2011 32 7
  • An exploratory pilot study into the association between microcirculatory parameters derived by MRI-based pharmacokinetic analysis and glucose utilization estimated by PET-CT imaging in head and neck cancer
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