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Research ArticleInterventional
Open Access

Hemodynamics and Bleb Formation in Intracranial Aneurysms

J.R. Cebral, M. Sheridan and C.M. Putman
American Journal of Neuroradiology February 2010, 31 (2) 304-310; DOI: https://doi.org/10.3174/ajnr.A1819
J.R. Cebral
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M. Sheridan
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C.M. Putman
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    Fig 1.

    Vascular models of an aneurysm before (pre) and after (post) bleb formation created from 3DRA image.

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    Fig 2.

    Aneurysm and bleb characterization.

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    Fig 3.

    Visualizations of WSS distributions before (left) and after (right) bleb formation for all aneurysms in the sample. The regions where the blebs were smoothed out are indicated in the prebleb formation models.

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    Fig 4.

    Visualizations of WSS distributions before (left column) and after (right column) bleb formation in an aneurysm with WSS higher than the parent artery (top row), lower than the parent artery (middle row), and an example of the reduction of the WSS at the flow impaction zone when blebs are formed (bottom row).

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    Fig 5.

    Visualizations of intra-aneurysmal flow structures before (left column) and after (right column) bleb formation. Top row: flow patterns showing the bleb at the flow impaction region. Bottom row: examples of an aneurysm with a bleb aligned with the inflow jet.

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American Journal of Neuroradiology: 31 (2)
American Journal of Neuroradiology
Vol. 31, Issue 2
1 Feb 2010
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J.R. Cebral, M. Sheridan, C.M. Putman
Hemodynamics and Bleb Formation in Intracranial Aneurysms
American Journal of Neuroradiology Feb 2010, 31 (2) 304-310; DOI: 10.3174/ajnr.A1819

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Hemodynamics and Bleb Formation in Intracranial Aneurysms
J.R. Cebral, M. Sheridan, C.M. Putman
American Journal of Neuroradiology Feb 2010, 31 (2) 304-310; DOI: 10.3174/ajnr.A1819
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  • Computational Fluid Dynamics in Highly Complex Geometries Using MPI-Parallel Lattice Boltzmann Methods: A Biomedical Engineering Application
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  • Towards the Clinical utility of CFD for assessment of intracranial aneurysm rupture - a systematic review and novel parameter-ranking tool
  • Critical role of angiographic acquisition modality and reconstruction on morphometric and haemodynamic analysis of intracranial aneurysms
  • Inflow Jet Patterns of Unruptured Cerebral Aneurysms Based on the Flow Velocity in the Parent Artery: Evaluation Using 4D Flow MRI
  • Analysis of hemodynamics and wall mechanics at sites of cerebral aneurysm rupture
  • Parent Artery Curvature Influences Inflow Zone Location of Unruptured Sidewall Internal Carotid Artery Aneurysms
  • CFD: Computational Fluid Dynamics or Confounding Factor Dissemination? The Role of Hemodynamics in Intracranial Aneurysm Rupture Risk Assessment
  • Generalized versus Patient-Specific Inflow Boundary Conditions in Computational Fluid Dynamics Simulations of Cerebral Aneurysmal Hemodynamics
  • Wall shear stress association with rupture status in volume matched sidewall aneurysms
  • Role of Fluid Dynamics and Inflammation in Intracranial Aneurysm Formation
  • Quantification of speed-up and accuracy of multi-CPU computational flow dynamics simulations of hemodynamics in a posterior communicating artery aneurysm of complex geometry
  • Effect of Bifurcation Angle Configuration and Ratio of Daughter Diameters on Hemodynamics of Bifurcation Aneurysms
  • Hemodynamics of Cerebral Aneurysm Initiation: The Role of Wall Shear Stress and Spatial Wall Shear Stress Gradient
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More in this TOC Section

  • Endovascular Management of Intracranial Dural AVFs: Transvenous Approach
  • A Meta-analysis of Combined Aspiration Catheter and Stent Retriever versus Stent Retriever Alone for Large-Vessel Occlusion Ischemic Stroke
  • Follow-up of Intracranial Aneurysms Treated by Flow Diverters: Evaluation of Parent Artery Patency Using 3D-T1 Gradient Recalled-Echo Imaging with 2-Point Dixon in Combination with 3D-TOF-MRA with Compressed Sensing
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