Acute Hydrocephalus and Cerebral Perfusion after Aneurysmal Subarachnoid Hemorrhage

American Journal of Neuroradiology

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Fig 1.
A, ROIs that were drawn in the flow territories of the anterior cerebral artery (cortex: ROIs 1 and 2, basal ganglia: ROIs 5 and 6) and the middle cerebral artery (cortex: ROIs 3 and 4, basal ganglia: ROIs 7 and 8). B, In the periventricular white matter, ROIs were drawn anterior (ROIs 9 and 10) and on either side (ROIs 11 and 12) of the lateral ventricles.

Table 1:

Patient characteristics

Characteristic	Hydrocephalus	No Hydrocephalus
No. of patients (%)	49 (36)	89 (65)
Mean age (SD)	59.8 (13)	54.1 (14)
Women (%)	31 (63)	65 (73)
Admission WFNS score (%)
I	20 (41)	47 (53)
II	7 (14)	12 (14)
III	7 (14)	9 (10)
IV	11 (22)	12 (13)
V	4 (8)	9 (10)
Day (after SAH) of admission scan (%)
0	33 (67)	56 (63)
1	10 (20)	24 (27)
2	4 (8)	5 (6)
3	2 (4)	4 (5)
Amount of blood (Hijdra score)
Median cisternal sum score	24	22
Median ventricular sum score	2	0
Mean bicaudate index (SD)	0.22 (0.3)	0.14 (0.3)
Mean relative bicaudate index (SD)	1.2 (0.1)	0.75 (0.2)
Aneurysm location (%)
Anterior communicating^a	22 (45)	41 (46)
Internal carotid artery	6 (12)	14 (16)
Middle cerebral artery	6 (12)	17 (19)
Posterior^b	15 (31)	17 (19)

Note:—WFNS indicates World Federation of Neurologic Surgeons; SAH, subarachnoid hemorrhage.
^a Includes the anterior cerebral artery.
^b Basilar or vertebral arteries.

Table 2:

Cerebral perfusion in patients with and without hydrocephalus

	Hydro-cephalus	Cortex	Difference of Means (95% CI; P Value)	Basal Ganglia	Difference of Means (95% CI; P Value)	Periventricular White Matter	Difference of Means (95% CI; P Value)
Mean CBV (mL/100 g) (SD)	No	4.0 (1.2)	−0.1 (−0.4 to 0.1; P = .41)	4.1 (1.2)	−0.2 (−0.5 to 0.2; P = .35)	3.1 (0.9)	0.1 (−0.2 to 0.3; P = .61)
Mean CBV (mL/100 g) (SD)	Yes	4.1 (1.0)	−0.1 (−0.4 to 0.1; P = .41)	4.3 (1.3)	−0.2 (−0.5 to 0.2; P = .35)	3.0 (0.9)	0.1 (−0.2 to 0.3; P = .61)
Mean CBF (mL/100 g/min) (SD)	No	53.4 (18.2)	1.8 (−2.8 to 6.4; P = .43)	62.7 (21.1)	6.2 (1.6 to 11.0; P = .014)	32.4 (11.0)	3.8 (0.9 to 6.8; P = .005)
Mean CBF (mL/100 g/min) (SD)	Yes	51.6 (18.6)	1.8 (−2.8 to 6.4; P = .43)	56.5 (17.2)	6.2 (1.6 to 11.0; P = .014)	28.6 (10.3)	3.8 (0.9 to 6.8; P = .005)
Mean MTT (seconds) (SD)	No	4.9 (1.8)	−0.5 (−1.1 to −0.1; P = .048)	4.3 (1.7)	−0.7 (−1.1 to −0.1; P = .008)	6.0 (1.9)	−0.9 (−1.6 to −0.2; P = .004)
Mean MTT (seconds) (SD)	Yes	5.4 (2.7)	−0.5 (−1.1 to −0.1; P = .048)	5.0 (1.9)	−0.7 (−1.1 to −0.1; P = .008)	6.9 (2.8)	−0.9 (−1.6 to −0.2; P = .004)
Mean TTP (seconds) (SD)	No	23.4 (5.5)	−1.6 (−3.0 to −0.1; P = .28)	23.1 (5.6)	−1.4 (−2.9 to 0.1; P = .056)	25.7 (4.6)	−1.7 (−3.1 to −0.3; P = .034)
Mean TTP (seconds) (SD)	Yes	25.0 (6.0)	−1.6 (−3.0 to −0.1; P = .28)	24.5 (5.9)	−1.4 (−2.9 to 0.1; P = .056)	27.4 (5.4)	−1.7 (−3.1 to −0.3; P = .034)