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OtherHead and Neck Imaging

Window Settings for the Study of Calcified Carotid Plaques with Multidetector CT Angiography

L. Saba and G. Mallarin
American Journal of Neuroradiology August 2009, 30 (7) 1445-1450; DOI: https://doi.org/10.3174/ajnr.A1509
L. Saba
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G. Mallarin
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    Fig 1.

    A, Scatterplot between width and level (NASCET II-V) with linear regression through the origin, with a 99% mean predictive interval and 99% individual predictive interval. Width = 2.81 × Level. B, Scatterplot between intraluminal Hounsfield unit values (IntraluminHU) and level (NASCET II-V) with linear regression through the origin with a 99% mean predictive interval and a 99% individual predictive interval. Level = 0.72 × Intraluminal HU. C, Scatterplot between intraluminal Hounsfield unit value and width (NASCET II-V) with linear regression through the origin with a 99% mean predictive interval and 99% individual predictive interval. Width = 2.07 × Intraluminal HU Value.

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    Fig 2.

    Bland-Altman plots of intraobserver variability in the window width (A), window level (B), and intraluminal Hounsfield unit measurements (C). Obs indicates observer. Intralumin-HU indicates intraluminal Hounsfield unit.

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    Fig 3.

    A 68-year-old man. CT axial images applying different window parameters. A and B, Intraluminal Hounsfield unit value is 547 (right bulbus). With a 275 width and 30 level (A) and 600/200 (B), it is not possible to differentiate lumen from calcification. C, With 800/300, it is possible to differentiate opacified lumen and calcification. D, By using equations described in this article, we obtained window parameters of 1132/394; a clear differentiation between lumen and parietal calcifications is visible.

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    Table 1:

    κ statistics for the comparison of stenosis grading between observer 1 and observer 2

    NASCET ClassObserver 2Total
    IIIIIIVV
    Observer 1
        II1200012
        III1281131
        IV0228333
        V0036265
    Total13303266141
    • Note:—NASCET indicates North American Symptomatic Carotid Endarterectomy Trial.

    • *Measurements were made by selecting a plane perpendicular to the lumen center line.

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    Table 2:

    Pearson correlation calculation between window level, window width, and intraluminal Hounsfield unit values in NASCET classes*

    Pearson Correlation VariablesNASCET II-V (r)NASCET II (r)NASCET III (r)NASCET IV (r)NASCET V (r)
    Window level−window width0.8910.9280.8900.9050.881
    IntraluminHU value−window level0.7430.7530.7180.6890.763
    IntraluminHU value−window width0.8080.7240.7380.7860.836
    • Note:—IntraluminHU indicates intraluminal Hounsfield unit.

    • * Correlation is significant at the 0.01 level (2-tailed).

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American Journal of Neuroradiology: 30 (7)
American Journal of Neuroradiology
Vol. 30, Issue 7
August 2009
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L. Saba, G. Mallarin
Window Settings for the Study of Calcified Carotid Plaques with Multidetector CT Angiography
American Journal of Neuroradiology Aug 2009, 30 (7) 1445-1450; DOI: 10.3174/ajnr.A1509

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Window Settings for the Study of Calcified Carotid Plaques with Multidetector CT Angiography
L. Saba, G. Mallarin
American Journal of Neuroradiology Aug 2009, 30 (7) 1445-1450; DOI: 10.3174/ajnr.A1509
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