Article Figures & Data
Figures
- Fig 1.
Interobserver agreement scatterplots (n = 319). A, Stenosis measures (in millimeters); ICC, 0.90 (95% CI, 0.88–0.92). B, Distal ICA measures (in millimeters); ICC, 0.79 (95% CI, 0.75–0.83).
- Fig 2.
Gender-specific linear regression lines between mean millimeter stenosis and their corresponding percent stenosis values. A, Female regression line (n = 157; adjusted R2 = 0.93). B, Male regression line (n = 162; adjusted R2= 0.90).
- Fig 3.
Gender-specific estimated percentage stenosis values (presented as 95% predictive intervals) corresponding to specific millimeter stenosis measures, calculated from the respective gender-specific linear regression models. The shaded areas represent the millimeter stenosis ranges that correspond to the estimated percentage stenosis ranges that include the 70% and 50% stenosis cut-off values (severe and moderate stenosis, respectively).
- Fig 4.
Severe stenosis ROC curves. A, Female (n = 157), area under the curve = 0.98 (95% CI, 0.96–1.0). B, Male (n = 162), area under the curve = 0.98 (95% CI, 0.96–1.0).
- Fig 5.
Moderate stenosis ROC curves. A, Female (n = 157), area under the curve = 0.98 (95% CI, 0.97–1.0). B, Male (n = 162), area under the curve = 0.98 (95% CI, 0.96–1.0).
Tables
- Table 1:
Range of gender-specific direct millimeter stenosis values that correspond to the percent stenosis ranges estimating severe stenosis (≥70%) as in NASCET
Severe Stenosis (mm) Sensitivity Specificity LR+ LR− 10% Prevalence 30% Prevalence PPV NPV PPV NPV Women 1.1 78.9 98.6 54.5 0.2 86.2 97.7 96.0 91.6 1.2 78.9 94.2 13.6 0.2 60.2 97.6 85.4 91.2 1.3 94.7 90.6 10.1 0.06 52.8 99.4 81.2 97.6 1.4 94.7 83.3 5.7 0.06 38.7 99.3 70.8 97.3 Men 1.1 62.5 98.6 45.6 0.4 83.2 95.9 95.0 86.0 1.2 87.5 96.6 25.6 0.1 74.1 98.6 91.7 94.7 1.3 93.8 93.8 15.2 0.07 62.7 99.3 86.6 97.2 1.4 93.8 90.4 9.8 0.07 52.1 99.2 80.7 97.1 Note:—LR+ indicates positive likelihood ratio; LR−, negative likelihood ratio; PPV, positive predictive value; NPV, negative predictive value.
- Table 2:
Range of gender-specific direct millimeter stenosis values that correspond to the percent stenosis ranges estimating moderate stenosis (≥50%) as in NASCET
≥ Moderate Stenosis (mm) Sensitivity Specificity LR+ LR− 40% Prevalence 60% Prevalence PPV NPV PPV NPV Women 1.9 79.8 98.6 58.2 0.2 97.4 88.0 98.8 76.5 2.0 86.9 94.5 15.9 0.1 91.3 91.5 96.0 82.8 2.1 92.9 91.8 11.3 0.08 88.3 95.1 94.4 89.6 2.2 94.0 89.0 8.6 0.07 85.1 95.7 92.8 90.8 2.3 96.4 84.9 6.4 0.04 81.0 97.3 90.5 94.0 Men 1.9 79.7 97.8 37.1 0.2 96.0 87.8 98.2 76.3 2.0 82.6 96.8 25.6 0.2 94.5 89.3 97.5 78.8 2.1 88.4 94.6 16.4 0.1 91.6 92.4 96.1 84.5 2.2 92.8 90.3 9.6 0.08 86.4 95.0 93.5 89.3 2.3 95.7 87.1 7.4 0.05 83.2 96.8 91.8 93.1 2.4 95.7 81.7 5.2 0.05 77.7 96.6 88.7 92.7 Note:—LR+ indicates positive likelihood ratio; LR−, negative likelihood ratio; PPV, positive predictive value; NPV, negative predictive value.
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