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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleSpine Imaging and Spine Image-Guided Interventions

Diffusion Tensor MR Imaging in Cervical Spine Trauma

K. Shanmuganathan, R.P. Gullapalli, J. Zhuo and S.E. Mirvis
American Journal of Neuroradiology April 2008, 29 (4) 655-659; DOI: https://doi.org/10.3174/ajnr.A0916
K. Shanmuganathan
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R.P. Gullapalli
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J. Zhuo
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S.E. Mirvis
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    Fig 1.

    Images showing the placement of regions of interest in the sagittal T2-weighted image (A), FA image (B), and the corresponding ellipsoid representation of the tensor at each level of the cord (C).

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    Fig 2.

    A 56-year-old man admitted following a fall, with central cord syndrome. A, T2-weighted image shows a cord contusion (arrowhead) posterior to the C4-5 disk space. Ellipsoid representation of the tensor of the axial cervical cord of the patient and healthy volunteer at corresponding anatomic levels of the upper cord (B), adjacent to the contusion (C), cord contusion (D), and the lower cord (E) shows abnormal ellipsoid representation of the cord at and away from the cord contusion, where the conventional MR imaging shows no signal-intensity abnormality

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    Fig 3.

    Comparison of whole spine control (n = 8) DTI parameters with the patient population (n = 16), patients exhibiting hemorrhagic (Hem) injury (n = 6), patients with quadriplegia (Quads, n = 7), and site of injury (n = 11).

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  • Regional DTI parameters of the normal cord in control individuals and patients

    ParametersControlPatient
    UpperMidLowerUpperMidLower
    ADC (*10−3 mm2/s)0.83 ± 0.070.97 ± 0.110.97 ± 0.110.71 ± 0.130.77 ± 0.130.74 ± 0.13
        P value.013.0005.00013
    FA0.64 ± 0.080.69 ± 0.060.63 ± 0.060.63 ± 0.090.64 ± 0.080.60 ± 0.08
        P value.378.075.187
    RA0.63 ± 0.120.68 ± 0.090.59 ± 0.080.59 ± 0.120.60 ± 0.10.53 ± 0.1
        P value.248.037.099
    VR0.53 ± 0.150.49 ± 0.110.59 ± 0.090.53 ± 0.150.55 ± 0.120.61 ± 0.13
        P value.49.135.381
    E1 (*10−3 mm2/s)1.54 ± 0.151.88 ± 0.21.75 ± 0.151.25 ± 0.231.40 ± 0.271.27 ± 0.23
        P value.0018.0001.000105
    E2 (*10−3 mm2/s)0.63 ± 0.090.68 ± 0.100.74 ± 0.120.62 ± 0.140.64 ± 0.110.67 ± 0.1
        P value.393.199.063
    E3 (*10−3 mm2/s)0.32 ± 0.10.36 ± 0.110.42 ± 0.110.25 ± 0.110.29 ± 0.080.29 ± 0.13
        P value.09.039.01
    • Note:—Bold indicates P value < .05; ADC, apparent diffusion coefficient; FA, fractional anisotropy; RA, relative anisotropy; VR, volume ratio; E1, eigenvalue E1.

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American Journal of Neuroradiology: 29 (4)
American Journal of Neuroradiology
Vol. 29, Issue 4
April 2008
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Cite this article
K. Shanmuganathan, R.P. Gullapalli, J. Zhuo, S.E. Mirvis
Diffusion Tensor MR Imaging in Cervical Spine Trauma
American Journal of Neuroradiology Apr 2008, 29 (4) 655-659; DOI: 10.3174/ajnr.A0916

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Diffusion Tensor MR Imaging in Cervical Spine Trauma
K. Shanmuganathan, R.P. Gullapalli, J. Zhuo, S.E. Mirvis
American Journal of Neuroradiology Apr 2008, 29 (4) 655-659; DOI: 10.3174/ajnr.A0916
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  • Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function
  • Cervical Spinal Cord DTI Is Improved by Reduced FOV with Specific Balance between the Number of Diffusion Gradient Directions and Averages
  • Pulse-Triggered DTI Sequence with Reduced FOV and Coronal Acquisition at 3T for the Assessment of the Cervical Spinal Cord in Patients with Myelitis
  • Diffusion tensor imaging of the spinal cord and its clinical applications
  • Diffusion Tensor Imaging of the Pediatric Spinal Cord at 1.5T: Preliminary Results
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More in this TOC Section

  • Dynamic CT Myelography: Patient Positioning
  • Evaluation of SIH MR Scoring Systems in Normals
  • Management Outcomes For VO Spine Biopsy
Show more SPINE IMAGING AND SPINE IMAGE-GUIDED INTERVENTIONS

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