Article Figures & Data
Tables
- Table 1:
Univariate analysis of predictors of PH and HI after multimodal endovascular therapy for acute ischemic stroke
Variable PH No PH P HI No HI P (N = 24) N (%) (N = 161) N (%) (N = 45) N (%) (N = 140) N (%) Demographics Age (mean ± SD), years 68 ± 12 64 ± 13 .13 64 ± 14 64 ± 13 .96 NIHSS (mean ± SD) 18 ± 5 17 ± 4 .35 18 ± 04 17 ± 4 .20 Hypertension 13 (54) 100 (62) .37 30 (67) 82 (59) .59 Diabetes mellitus 4 (17) 38 (24) .67 9 (20) 32 (23) .69 Atrial fibrillation 8 (33) 44 (27) .63 16 (36) 36 (26) .34 Hyperlipidemia 8 (33) 61 (38) .66 14 (31) 55 (39) .29 Coronary artery disease 12 (50) 54 (34) .18 12 (27) 54 (39) .15 Hyperglycemia 9 (38) 34 (21) .04 12 (27) 30 (21) .30 Location of thrombus CCA bifurcation 0 (0) 8 (6) .61 1 (2) 7 (5) .68 ICA terminus 6 (25) 39 (24) .89 10 (22) 35 (25) .65 M1 MCA 10 (42) 68 (42) .92 23 (51) 55 (39) .22 M2 MCA 1 (4) 6 (4) .83 3 (7) 4 (3) .37 Vertebrobasilar system 1 (4) 26 (16) .09 7 (16) 20 (14) .38 Tandem occlusion 6 (25) 15 (9) .03 4 (9) 17 (12) .78 Type of intervention IV tPA 13 (54) 60 (37) .09 20 (44) 53 (38) .37 IV urokinase 7 (29) 27 (18) .12 8 (18) 26 (19) .87 IA tPA 11 (46) 84 (52) .66 22 (49) 73 (52) .61 IV IIb/IIIa 8 (33) 63 (39) .66 17 (38) 54 (39) .87 IV IIb/IIIa + thrombolytic 5 (21) 36 (22) .93 10 (22) 31 (22) .93 Angioplasty 7 (29) 65 (40) .37 18 (40) 54 (39) .89 Snare/Merci 7 (29) 20 (12) .06 6 (13) 21 (15) .70 Extracranial stent 4 (17) 27 (17) .96 5 (19) 26 (14) .38 Intracranial stent 1 (4) 25 (16) .11 6 (13) 20 (14) .88 IV tPA + IA urokinase 4 (17) 8 (5) .045 3 (7) 9 (6) .69 IV tPA + IA tPA 6 (25) 32 (20) .59 9 (20) 29 (21) .97 IV tPA + any IA thrombolytic 10 (42) 40 (25) .05 12 (27) 38 (27) .91 Postintervention TIMI 2 or 3 flow 14 (58) 102 (63) .63 26 (58) 90 (64) .48 CT imaging preprocedure ASPECTS 1 (4) 16 (10) .47 10 (22) 7 (5) .002 Neuroimaging postprocedure TIMI 2 or 3 flow + ASPECTS ≤7 1 (4) 8 (5) .64 5 (11) 4 (1) .05 Note:—PH indicates parenchymal hematoma; HI, hemorrhagic transformation; CCA, common carotid artery; ICA, internal carotid artery; MCA, middle cerebral artery; IIb/IIA, glycoprotein receptor IIb/IIa antagonist; NIHSS, National Institutes of Health Stroke Scale; TIMI, Thrombolysis in Myocardial Infarction; ASPECTS, Alberta Stroke Programme Early CT Score. Boldfaced numbers indicate which parameters from the univariate analysis were entered into the multiple logistic analysis.
- Table 2:
Independent predictors of parenchymal hematoma after multimodal treatment of acute ischemic stroke
Variable OR 95%CI P Parenchymal hematoma Hyperglycemia 2.8 1.05–7.7 .043 Tandem occlusion 4.6 1.35–6.5 .016 IV tPA + IA urokinase 5.1 1.07–25.0 .041 Hemorrhagic infarction Admission ASPECTS ≤7 1.9 1.3–2.7 .01 Note:—CI indicates confidence interval; OR, odds ratio.