Skip to main content
Advertisement
  • Main menu
  • User menu
  • Search
  • English ▼
    • English
    • Afrikaans
    • Albanian
    • Amharic
    • Arabic
    • Armenian
    • Azerbaijani
    • Basque
    • Belarusian
    • Bengali
    • Bosnian
    • Bulgarian
    • Catalan
    • Cebuano
    • Chichewa
    • Chinese (Simplified)
    • Chinese (Traditional)
    • Corsican
    • Croatian
    • Czech
    • Danish
    • Dutch
    • Esperanto
    • Estonian
    • Filipino
    • Finnish
    • French
    • Frisian
    • Galician
    • Georgian
    • German
    • Greek
    • Gujarati
    • Haitian Creole
    • Hausa
    • Hawaiian
    • Hebrew
    • Hindi
    • Hmong
    • Hungarian
    • Icelandic
    • Igbo
    • Indonesian
    • Irish
    • Italian
    • Japanese
    • Javanese
    • Kannada
    • Kazakh
    • Khmer
    • Korean
    • Kurdish (Kurmanji)
    • Kyrgyz
    • Lao
    • Latin
    • Latvian
    • Lithuanian
    • Luxembourgish
    • Macedonian
    • Malagasy
    • Malay
    • Malayalam
    • Maltese
    • Maori
    • Marathi
    • Mongolian
    • Myanmar (Burmese)
    • Nepali
    • Norwegian
    • Pashto
    • Persian
    • Polish
    • Portuguese
    • Punjabi
    • Romanian
    • Russian
    • Samoan
    • Scottish Gaelic
    • Serbian
    • Sesotho
    • Shona
    • Sindhi
    • Sinhala
    • Slovak
    • Slovenian
    • Somali
    • Spanish
    • Sudanese
    • Swahili
    • Swedish
    • Tajik
    • Tamil
    • Telugu
    • Thai
    • Turkish
    • Ukrainian
    • Urdu
    • Uzbek
    • Vietnamese
    • Welsh
    • Xhosa
    • Yiddish
    • Yoruba
    • Zulu

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • Advancing NeuroMRI with High-Relaxivity Contrast Agents
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

English ▼
  • English
  • Afrikaans
  • Albanian
  • Amharic
  • Arabic
  • Armenian
  • Azerbaijani
  • Basque
  • Belarusian
  • Bengali
  • Bosnian
  • Bulgarian
  • Catalan
  • Cebuano
  • Chichewa
  • Chinese (Simplified)
  • Chinese (Traditional)
  • Corsican
  • Croatian
  • Czech
  • Danish
  • Dutch
  • Esperanto
  • Estonian
  • Filipino
  • Finnish
  • French
  • Frisian
  • Galician
  • Georgian
  • German
  • Greek
  • Gujarati
  • Haitian Creole
  • Hausa
  • Hawaiian
  • Hebrew
  • Hindi
  • Hmong
  • Hungarian
  • Icelandic
  • Igbo
  • Indonesian
  • Irish
  • Italian
  • Japanese
  • Javanese
  • Kannada
  • Kazakh
  • Khmer
  • Korean
  • Kurdish (Kurmanji)
  • Kyrgyz
  • Lao
  • Latin
  • Latvian
  • Lithuanian
  • Luxembourgish
  • Macedonian
  • Malagasy
  • Malay
  • Malayalam
  • Maltese
  • Maori
  • Marathi
  • Mongolian
  • Myanmar (Burmese)
  • Nepali
  • Norwegian
  • Pashto
  • Persian
  • Polish
  • Portuguese
  • Punjabi
  • Romanian
  • Russian
  • Samoan
  • Scottish Gaelic
  • Serbian
  • Sesotho
  • Shona
  • Sindhi
  • Sinhala
  • Slovak
  • Slovenian
  • Somali
  • Spanish
  • Sudanese
  • Swahili
  • Swedish
  • Tajik
  • Tamil
  • Telugu
  • Thai
  • Turkish
  • Ukrainian
  • Urdu
  • Uzbek
  • Vietnamese
  • Welsh
  • Xhosa
  • Yiddish
  • Yoruba
  • Zulu
  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • Advancing NeuroMRI with High-Relaxivity Contrast Agents
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates


Improved Turnaround Times | Median time to first decision: 12 days

Research ArticlePediatric Neuroimaging

Angiography of Primary Central Nervous System Angiitis of Childhood: Conventional Angiography versus Magnetic Resonance Angiography at Presentation

R.I. Aviv, S.M. Benseler, G. DeVeber, E.D. Silverman, P.N. Tyrrell, L.M. Tsang and D. Armstrong
American Journal of Neuroradiology January 2007, 28 (1) 9-15;
R.I. Aviv
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S.M. Benseler
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G. DeVeber
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
E.D. Silverman
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
P.N. Tyrrell
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L.M. Tsang
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D. Armstrong
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Fig 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 1.

    Representative MRA and angiographic images. Aggressive appearing lesions were those that demonstrated multiple short segment irregularity with alternating narrowing and dilation (beading) (white arrow) (A) or multiple longer segmental narrowing with normal intervening vessel (black arrowheads) (B). Aneurysms (not shown) were included in this definition. Benign appearing lesions (C) had smooth (white arrows), often solitary, tapered (white arrowhead) narrowing that could be concentric or eccentric. Incidental hypoplasia of the ipsilateral A1 is noted.

  • Fig 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 2.

    Good agreement of CA (A) and (B) MRA for right ICA. Both modalities demonstrate tapered narrowing of the terminal carotid and proximal M1 and A1 (carotid terminus) with focal midM1 dilation and distal narrowing. Both modalities identify beading of the proximal A1 (black arrows).

  • Fig 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 3.

    Abnormal CA (A) in the context of normal MRA (B) in a patient with a lone focal stenosis of the left PcomA. No other CA abnormality was present. MR imaging was abnormal maintaining suspicion for vasculitis despite a negative MRA.

  • Fig 4.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 4.

    A, Occlusion of the P3 segment of the right PCA on TOF MRA (white arrowhead). Inferior temporal branches (white arrows) are slightly more prominent than on the contralateral side but B, extent of collaterals and reconstitution of the distal PCA (black arrow) best seen on CA.

Tables

  • Figures
    • View popup
    Table 1:

    Demographic distribution of abnormality in patients with abnormal MRA and CA

    MRA Patients (%)CA Patients (%)P Value
    Unilateral lesions*19 (79.2)19 (90.5)1.0
    Bilateral lesions5 (20.8)2 (9.5).42
    Any proximal lesion† regardless of whether distal lesion22 (87.5)18 (85.7).28
    Distal lesion only2 (8.3)3 (14.3).18
    Anterior circulation only‡19 (79.2)15 (71.4).36
    Posterior circulation only2 (8.3)3 (14.3)1.00
    Anterior and posterior3 (12.5)3 (14.3)1.00
    Ipsilateral ≥ 2 lesions§16 (66.7)16 (76.2)1.00
    Total lesions ≥ 53 (12.5)4 (19.0).29
    Benign appearance19 (79.2)16 (76.2).50
    Aggressive appearance5 (20.8)5 (23.8)1.00
    • Note:— MRA indicates MR angiography; CA, conventional angiography. Twenty-one CA and 24 MRA studies were abnormal and compared in 25 patients.

    • * Unilateral vs bilateral, P <0.05.

    • † Proximal vs distal, P = .08.

    • ‡ Anterior vs posterior, P = .06.

    • § Multifocal vs unifocal, P = .09.

    • View popup
    Table 2:

    Distribution of lesions on MRA and CA

    LesionsMRA (n = 62)CA (n = 64)P Value
    ICA11 (17.7%)11 (17.5%).94
    ACA11 (17.7%)17 (27.0%).23
    MCA34 (54.8%)26 (41.3%).11
        M12416.10
        M2109.75
        M401.32
    PCA5 (8.1%)9 (14.3%).28
        P122.97
        P237.21
    Vertebrobasilar00
    Anterior choroidal00
    PcomA1 (1.6%)1 (1.6%).98
    • Note:— MRA indicates MR angiography; CA, conventional angiography; ICA, internal carotid artery; ACA, anterior cerebral artery; MCA, middle cerebral artery; PCA, posterior cerebral artery; PcomA, posterior communicating artery.

    • View popup
    Table 3:

    Morphology of CA and MRA stenoses

    MorphologyMRA (n = 56)CA (n = 54)P Value
    Smooth45 (80.4%)45 (83.3%).80
    Irregular11 (19.6%)9 (16.7%).80
    Concentric54 (96.4%)50 (92.6%).57
    Eccentric2 (3.6%)4 (7.4%).57
    Graduated11 (19.6%)11 (20.4%).95
    Single52 (92.9%)48 (88.9%).64
    Beading6 (10.7%)6 (11.1%).97
    Multiple2 (3.6%)6 (11.1%).33
    • Note:— CA indicates conventional angiography; MRA, MR angiography. Data exclude occlusions and aneurysms.

    • View popup
    Table 4:

    Vascular segmental location of MRA false-negatives

    LocationNumber (n = 19)
    A14 (21.1%)
    Cavernous carotid3 (15.8%)
    M12 (10.5%)
    M24 (21.1%)
    M41 (5.3%)
    P11 (5.3%)
    P21 (5.3%)
    PcomA1 (5.3%)
    Pericallosal2 (10.5%)
    • Note:— MRA indicates MR angiography; PcomA, posterior communicating artery.

    • View popup
    Table 5:

    Stenosis quantification

    CA StenosisNumber of Lesions on CAMRA Agreement LesionsMRA Falsely Upgraded LesionsMRA Falsely Downgraded LesionsMRA False-Negatives
    <50%204 (20%)7 (35%)9 (45%)
    50–<75%2512 (48%)6 (24%)1 (4%)6 (24%)
    75–99%97 (78%)1 (11%)1 (11%)
    100%81 (13%)4 (50%)3 (38%)
    • Note:— MRA indicates MR angiography; CA, conventional angiography. Total MRA agreement is 43 lesions, excluding 2 aneurysms. Number of lesions correctly graded or up- and downgraded by MRA when compared with CA (n = 62 CA lesions; excludes 2 aneurysms)

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 28 (1)
American Journal of Neuroradiology
Vol. 28, Issue 1
January 2007
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article
Cite this article
0 Responses
Respond to this article
Share
Bookmark this article
Angiography of Primary Central Nervous System Angiitis of Childhood: Conventional Angiography versus Magnetic Resonance Angiography at Presentation
R.I. Aviv, S.M. Benseler, G. DeVeber, E.D. Silverman, P.N. Tyrrell, L.M. Tsang, D. Armstrong
American Journal of Neuroradiology Jan 2007, 28 (1) 9-15;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget

Jump to section

  • Article
    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • Conclusion
    • Acknowledgments
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Strategies for treatment of childhood primary angiitis of the central nervous system
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Clinical SVR of Fetal Brain MRI
  • Comparing MRI Perfusion in Pediatric Brain Tumors
  • Sodium MRI in Pediatric Brain Tumors
Show more PEDIATRIC NEUROIMAGING

Similar Articles

  • Amyloid-β-Related Angiitis: Neuroimaging FindingsAmyloid-β-Related Angiitis: Neuroimaging Findings
  • Magnetic Resonance Imaging versus Noncontrast Computed Tomography for Selecting Patients with Acute Ischemic Stroke of Large Vessel Occlusion for Endovascular Thrombectomy: A Systematic Review and Meta-Analysis
  • Predicting White Matter Hyperintensity: Leveraging Portable Magnetic Resonance Imaging for Accessible Brain Health Screening
  • Digital FDG-PET detects MYD88 mutation-driven glycolysis in primary central nervous system lymphoma
  • CNS Vasculitis in Autoimmune Diseases
See more
Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire
Email this Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Angiography of Primary Central Nervous System Angiitis of Childhood: Conventional Angiography versus Magnetic Resonance Angiography at Presentation
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
R.I. Aviv, S.M. Benseler, G. DeVeber, E.D. Silverman, P.N. Tyrrell, L.M. Tsang, D. Armstrong
Angiography of Primary Central Nervous System Angiitis of Childhood: Conventional Angiography versus Magnetic Resonance Angiography at Presentation
American Journal of Neuroradiology Jan 2007, 28 (1) 9-15;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

We use cookies on this site to enhance your user experience. By clicking any link on this page you are giving your consent for us to set cookies.