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Research ArticlePediatric Neuroimaging

Involvement of the Anterior Lobe of the Cerebellar Vermis in Perinatal Profound Hypoxia

D.J.A. Connolly, E. Widjaja and P.D. Griffiths
American Journal of Neuroradiology January 2007, 28 (1) 16-19;
D.J.A. Connolly
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E. Widjaja
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P.D. Griffiths
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  • Fig 1.
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    Fig 1.

    Five-year-old girl with athetoid spastic quadriplegia.

    A, Axial T2. Mild signal intensity change in the perirolandic white matter.

    B, Axial T2. Typical signal intensity change in the posterior putamen and the ventrolateral thalamus bilaterally.

    C, Axial T2. Typical signal intensity change in the anterior lobe of the vermis.

    D, Axial T1. Low T1 signal intensity change in the vermis.

    E, Axial FLAIR. High T2 signal intensity and cystic change.

    F, Coronal T2. Anterior lobe of vermis high T2 signal intensity change.

  • Fig 2.
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    Fig 2.

    Nine-month-old girl with dyskinetic cerebral palsy.

    A, Coronal T2. Central lobule of anterior lobe of the vermis high T2 signal intensity.

    B, Axial FLAIR. High T2 signal intensity and cystic change of anterior lobe of vermis.

    C, Sagittal T2. Central lobule of anterior lobe of vermis high T2 signal intensity.

  • Fig 3.
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    Fig 3.

    Seven-year-old boy with severe spastic quadriplegia.

    A, Axial T2. Severe signal intensity change and volume loss in the perirolandic white matter.

    B, Axial T2. Severe putaminal and thalamic volume loss and high T2 signal intensity bilaterally.

    C, Axial T2. Mild vermian high T2 signal intensity change.

Tables

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  • Patient clinical information and scores for brain damage secondary to hypoxic ischemic encephalopathy

    CaseAge (years)ApgarHeart Rate (bpm)PutamenThalamusPCWMTotal Score*VermisOthers
    1 minute5 minutes
    1466>100221500
    22138033281Hippocampus, caudate
    330270232710
    41501UR132610
    54176033391Hippocampus
    61126021141Hippocampus
    7115<2032271Hippocampus
    81412UR22261Hippocampus
    9603UR211400
    10769212500
    115213261Caudate
    1253512141Hippocampus
    13504UR332810
    141216103400
    1531540–6022151Hippocampus
    162415220410
    1713530250Caudate
    18510333910
    19100UR221500
    202UR22041Hippocampus
    2122370232700
    2225680333910
    2311160–8022261Hippocampus
    244487000220Caudate
    252466021360Caudate
    262202UR120310
    271567UR221500
    2846822261Hippocampus
    2971460220400
    30527<80323800
    • Note:—bpm indicates beats per minute; PCWM, paracentral white matter; UR, unrecordable.

    • * Total score of the abnormalities seen in putamen, thalamus, and paracentral white matter.

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American Journal of Neuroradiology: 28 (1)
American Journal of Neuroradiology
Vol. 28, Issue 1
January 2007
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Involvement of the Anterior Lobe of the Cerebellar Vermis in Perinatal Profound Hypoxia
D.J.A. Connolly, E. Widjaja, P.D. Griffiths
American Journal of Neuroradiology Jan 2007, 28 (1) 16-19;
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  • Injury to the Cerebellum in Term Asphyxiated Newborns Treated with Hypothermia
  • Low Cerebellar Vermis Volumes and Impaired Neuropsychologic Performance in Children Treated for Brain Tumors and Leukemia
  • Anatomic Localization of Dyskinesia in Children with "Profound" Perinatal Hypoxic-Ischemic Injury
  • Injury to the Developing Cerebellum: Mechanisms and Consequences
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D.J.A. Connolly, E. Widjaja, P.D. Griffiths
Involvement of the Anterior Lobe of the Cerebellar Vermis in Perinatal Profound Hypoxia
American Journal of Neuroradiology Jan 2007, 28 (1) 16-19;

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