Article Figures & Data
Figures
- Fig 1.
Example of patient with steroid-induced osteoporosis. Lateral thoracic spine plain-film radiograph. Initial prevertebroplasty film demonstrates T6 compression fracture.
- Fig 2.
Follow-up of the same patient. Lateral thoracic spine plain-film radiograph. One-year follow-up film demonstrates that the patient has undergone vertebroplasties of T5 through T8 and presents with a new fracture of T10 at the time of the study.
- Fig 3.
Primary and steroid-induced osteoporotic symptomatic refracture rates comparing 1-year follow-up with an extended follow-up
- Fig 4.
Graphs demonstrating relative frequencies of prevalent and incident fractures in both the steroid and osteoporosis groups.
Tables
Medical History No. of Patients COPD 18 Rheumatoid arthritis 5 Asthma 3 Polymyalgia rheumatica 3 Giant cell arteritis 2 Mixed connective tissue disease 1 CNS vasculitis 1 Myasthenia gravis 1 Pulmonary fibrosis 1 Other 2 Note:—COPD indicates chronic obstructive pulmonary disease; CNS, central nervous system.
- Table 2:
Odds ratio (OR) by location of incident fracture: steroid-induced compared to primary
Location of Incident Fracture T3–T11 T12–L1 L2–L5 OR (95% CI) 3.7 (1.56–8.62) 3.0 (1.24–.7.06) 1.5 (0.52–4.19) P value (group variable) .0029 .0146 .4313 Location Group Mean No. of Incident Fractures per Subject P-Value Any location Steroid 1.108 .0025 Primary 0.397 T3–T11 Steroid 0.568 .0009 Primary 0.149 T12–L1 Steroid 0.351 .0025 Primary 0.114 L2–L5 Steroid 0.189 .2081 Primary 0.134 Note:—Because all median are equal to O, means have been reported instead.
Percentage of Patients Having a Second Treatment Session Within 1 y of Initial Procedure Percentage of Refractured Patients Having a Third Treatment Session Within 1 y of Initial Procedure Average Available Cement Volumes for Patients Refracuring Within 1 y of Initial Procedure (cc) Average Time Between Treatment Sessions for Refracturing Patients Within 1 y of Initial Procedures No. of Patients Having Initial Procedure No. Refractured (2nd Procedure) % Refracturing No. Refractured (2nd Procedure) No. Refractured (3rd Procedure) % of Refractured Patients Having 3rd Procedure Δt Between 1st and 2nd procedure wk Δt Between 2nd and 3rd procedure wk Primary osteoporosis 350 72 20.6 72 23 31.9% 5.18 ± 2.58 11.3 12 Steroid-induced osteoporosis 37 14 37.8 14 6 42.9% 5.97 ± 3.02 7.93 10.8 Total 387 86 22.2 86 29 33.7% Relative risk 1.84 1.34† P value .0163 .3094 * Chi-squared analysis.
† Fisher exact test.
Vertebral Level Prevalent Fractures in Steroid Group Incident Fractures in Steroid Group (at 1 y) Prevalent Fractures in Primary Osteoporosis Group Incident Fractures in Primary Osteoporosis Group (at 1 y) T2 0 0 0 1 T3 0 0 4 0 T4 0 0 7 0 T5 2 1 7 2 T6 1 1 7 4 T7 2 3 24 5 T8 2 4 31 7 T9 3 2 23 9 T10 3 5 29 13 T11 6 5 44 11 T12 8 6 83 17 L1 6 7 98 19 L2 7 3 56 17 L3 9 2 54 12 L4 9 5 30 10 L5 4 0 12 4 Sacrum 0 0 0 1
