Functional MR Imaging of the Human Sensorimotor Cortex After Toe-to-Finger Transplantation

fMRI of the motor task (A) and the tactile sensory task (B) in subject 6. For both motor and sensory tasks, the main activation is located approximately two thirds of the distance from the lateral fissure to the interhemispheric fissure, corresponding to the hand area of the primary sensorimotor cortex. The activated volumes from the transplanted toe are greater than those from the normal finger. During the motor task, less-obvious activation is noted at the supplementary motor area along the midline (arrow in A) and bilateral secondary somatosensory areas along the lateral sulcus (arrowheads in A). Activation of the ipsilateral sensorimotor cortex is also noted during the motor task.