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Research ArticleBRAIN

Diffusion Anisotropy and Diffusivity of White Matter Tracts Within the Temporal Stem in Alzheimer Disease: Evaluation of the “Tract of Interest” by Diffusion Tensor Tractography

T. Taoka, S. Iwasaki, M. Sakamoto, H. Nakagawa, A. Fukusumi, K. Myochin, S. Hirohashi, T. Hoshida and K. Kichikawa
American Journal of Neuroradiology May 2006, 27 (5) 1040-1045;
T. Taoka
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S. Iwasaki
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M. Sakamoto
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H. Nakagawa
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A. Fukusumi
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K. Myochin
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S. Hirohashi
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T. Hoshida
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K. Kichikawa
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    Fig 1.

    Tractographies were drawn by using diffusion-weighted images (EPI imaging: TR/TE, 2300/122 ms; b = 1000 seconds/mm2; 6-axis encoding; FOV, 230 mm; matrix, 128 × 128; section spacing, 3.3 mm; section thickness, 3 mm; averaging, 6). Tractographies of the inferior occipitofrontal fasciculus (green), uncinate fasciculus (blue), and Meyer’s loop (yellow are shown). A, 3D view from the right upper; B, view from the bottom; C, view from the right; D, view from the front. Mean FA and ADC values were measured along these tracts of interest separately.

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    Fig 2.

    Comparison of mean FA, ADC, and number of voxels between patients with AD and controls. The patients with AD had significantly lower mean FA than the controls at both sides of the uncinate fasciculus and at the left side of the inferior occipitofrontal fasciculus (A). The patients with AD had significantly higher mean ADC than the controls at both sides of the uncinate fasciculus and inferior occipitofrontal fasciculus (B). There were no statistically significant differences between AD and controls for the number of voxels of the 3 tracts (C). R indicates right side; L, left side.

Tables

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  • Characteristics of the patients with Alzheimer disease

    Patient No./Age (y)/SexADASMMSE
    1/70/F17.015
    2/73/M15.021
    3/70/MN/A19
    4/73/M21.714
    5/72/F59.74
    6/70/F39.68
    7/76/FN/A9
    8/63/F31.711
    9/81/F24.020
    10/76/F41.37
    11/76/FN/A22
    12/87/F29.020
    13/68/M17.021
    14/75/F17.019
    15/76/F29.015
    • Note:— MMSE indicates Mini-Mental State Examination; ADAS, Alzheimer disease assessment scale.

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American Journal of Neuroradiology: 27 (5)
American Journal of Neuroradiology
Vol. 27, Issue 5
May 2006
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Cite this article
T. Taoka, S. Iwasaki, M. Sakamoto, H. Nakagawa, A. Fukusumi, K. Myochin, S. Hirohashi, T. Hoshida, K. Kichikawa
Diffusion Anisotropy and Diffusivity of White Matter Tracts Within the Temporal Stem in Alzheimer Disease: Evaluation of the “Tract of Interest” by Diffusion Tensor Tractography
American Journal of Neuroradiology May 2006, 27 (5) 1040-1045;

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Diffusion Anisotropy and Diffusivity of White Matter Tracts Within the Temporal Stem in Alzheimer Disease: Evaluation of the “Tract of Interest” by Diffusion Tensor Tractography
T. Taoka, S. Iwasaki, M. Sakamoto, H. Nakagawa, A. Fukusumi, K. Myochin, S. Hirohashi, T. Hoshida, K. Kichikawa
American Journal of Neuroradiology May 2006, 27 (5) 1040-1045;
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