Article Figures & Data
Figures
- Fig 1.
16-year-old boy with a purely cystic thyroid nodule (group A).
A, Ultrasonogram obtained before ethanol sclerotherapy shows a huge hemorrhagic thyroid nodule.
B, Ultrasonogram obtained 2 months after ethanol sclerotherapy reveals the complete disappearance of the cystic portion of the thyroid nodule and replacement by echogenic material.
C, Ultrasonogram obtained 9 months after ethanol sclerotherapy shows a decrease in the size of the postsclerotic thyroid nodule.
- Fig 2.
46-year-old woman with a cystic thyroid nodule (group B).
A, Ultrasonogram obtained before ethanol sclerotherapy shows a nearly pure thyroid cyst with an intracystic blood clot (arrow).
B, Ultrasonogram obtained after aspiration of infused ethanol shows the disappearance of the cystic portion and incomplete collapse of the cystic nodule due to the blood clot (arrow).
C, Ultrasonogram obtained 24 months after ethanol sclerotherapy shows the markedly decreased size of the thyroid nodule (arrow) without the cystic portion.
Tables
Group A Age (y)/Sex First Aspirates (ml) Infused Ethanol (ml) Total Procedure (min) First Follow-up Ultrasonography (mo) Therapeutic Result Complication 1 39/F 2 2 14 2 + 2 51/F 7 7 15 1 + 3 49/M 2 2 15 8 + 4 44/F 5 5 17 15 + 5 37/F 10 7 16 15 + Headache, dizziness 6 43/M 12 9 16 8 + 7 43/F 5 5 16 5 + 8 43/F 4 4 17 5 + Mild pain 9 58/F 8 8 16 3 + Moderate pain 10 36/F 6 6 15 15 + Mild pain 11 44/M 15 10 18 3 + Mild pain 12 27/F 7 6 15 7 + 13 38/F 5 5 17 3 + Facial flushing 14 47/F 13 12 15 1 + Mild pain 15 49/F 4 4 14 2 + 16 28/F 3.5 3.5 14 8 + 17 38/F 7 7 15 4 + 18 43/M 29 16 20 2 + 19 32/F 8 8 16 2 + Intracystic hemorrhage 20 44/F 2 3 20 2 + Mild pain 21 64/F 2 2 13 3 + Mild pain 22 46/M 4 4 15 2 + 23 47/M 40 15 20 4 + 24 75/F 20 12 17 3 + 25 47/M 10 7 16 2 + 26 35/F 20 17 19 2 + Mild pain 27 45/F 5 5 15 1 + Mild pain, drunken sense 28 16/M 96 20 23 2 + Facial flushing, drunken sense 29 70/F 135 30 29 3 + Perithyroidal leakage 30 47/F 8 8 15 2 − Mean 44.2 16.5 8.3 16.8 4.6 Note.—+ indicates complete disappearance of the cystic portion of the thyroid nodule; −, incomplete disappearance of the cystic portion of the thyroid nodule.
Group B Age (y)/Sex First Aspirates (ml) Infused Ethanol (ml) Ethanol Mixed Aspirates Total Procedure (min) First Follow-up Ultrasonography (mo) Therapeutic Result Complication 1 50/F 6 5 5 30 1 + 2 46/F 2 2 6 32 24 + Mild pain and intracystic hemorrhage 3 32/F 3.5 3 3.5 27 24 + 4 31/F 2 2 2 28 2 + 5 35/F 9 9 9 30 24 + 6 60/F 2 2 3 33 1 + Mild pain and intracystic hemorrhage 7 32/F 2 1.5 2 26 2 + 8 24/F 8 5 7 30 1 − Mild pain 9 66/F 2 2 2 31 1 + Mild pain 10 74/F 2 2 2 28 8 + 11 41/F 4 4 6 29 2 + Intracystic hemorrhage 12 45/M 5 5 5 27 3 + 13 31/F 8 6 8 32 1 + Mild pain 14 42/F 5 5 6 30 3 + Intracystic hemorrhage 15 32/F 4 4 4 28 6 + 16 60/F 8 9 7 30 3 + 17 43/F 2 2 1.2 29 4 + 18 66/F 20 12 7 33 1 + 19 37/F 25 20 20 31 2 + Drunken sense 20 55/M 4 4 4 27 2 + 21 46/F 4 4 2 33 1 + Mild dizziness 22 20/F 1 1.5 1 32 5 + Mild pain and facial flushing 23 49/F 4 4 3.5 28 1 + 24 29/F 1 1 1.2 30 1 + Mild pain 25 41/M 5 5 2 36 1 + Moderate pain and perithyroidal leakage 26 47/F 17 10 12 34 1 − Intracystic hemorrhage 27 66/F 4 4 4.5 31 3 + Intracystic hemorrhage 28 43/F 1 1 1 30 1 + 29 41/F 8 8 6.5 34 2 + Mild pain 30 75/M 50 20 22 38 1 + Mild pain and intracystic hemorrhage Mean 45.3 7.3 5.4 5.5 30.6 4.4 Note.—+ indicates complete disappearance of the cystic portion of the thyroid nodule; −, incomplete disappearance of the cystic portion of the thyroid nodule.
Group A (%) Group B (%) P Success result 29/30 (96.7) 28/30 (93.3) >.05 Complication Mild pain 8/30 (26.7) 9/30 (30) >.05 Moderate pain 1/30 (3.3) 1/30 (3.3) >.05 Facial flushing 2/30 (6.6) 1/30 (3.3) >.05 Drunken sense 2/30 (6.6) 1/30 (3.3) >.05 Headache 1/30 (3.3) 0/30 (0) >.05 Mild dizziness 1/30 (3.3) 1/30 (3.3) >.05 Perithyroidal ethanol leakage 1/30 (3.3) 1/30 (3.3) >.05 Intracystic hemorrage 1/30 (3.3) 7/30 (23.3) <.05 Complaint: double puncture − + <.001 Total procedure (min) 16.8 30.6 <.001
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