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Research ArticleBRAIN

Enhancing Gray-to-White Matter Contrast in 3T T1 Spin-Echo Brain Scans by Optimizing Flip Angle

Bernd L. Schmitz, Georg Grön, Florian Brausewetter, Martin H.K. Hoffmann and Andrik J. Aschoff
American Journal of Neuroradiology September 2005, 26 (8) 2000-2004;
Bernd L. Schmitz
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Georg Grön
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Florian Brausewetter
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Martin H.K. Hoffmann
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Andrik J. Aschoff
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    Fig 1.

    A, Black bar charts represent measured mean gray-to-white matter CNR at increasing flip angles. (Values were scaled to their grand mean to scale with predicted signal intensity.) Error is in SD. Striped bar charts represent predicted gray-to-white matter contrast.

    B, Black bar charts represent measured SNR at increasing flip angles. (Values were scaled to their grand mean to scale with predicted signal intensity.) Error is in SD. Striped bar charts represent predicted mean signal intensity for gray and white matter.

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    Fig 2.

    Bar charts represent mean subjective observer scores on image quality at increasing flip angles. Error is in SD. Observers were 2 experienced neuroradiologists.

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    Fig 3.

    Transversal sections of a prototypical subject scanned at different flip angles during a spin-echo T1 sequence at 3T B0 field strength to demonstrate the obvious decrease of gray-to-white matter contrast with increasing flip angle. Also noteworthy is the inverted T1 contrast in the basal ganglia region at a flip angle of 130°.

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American Journal of Neuroradiology: 26 (8)
American Journal of Neuroradiology
Vol. 26, Issue 8
1 Sep 2005
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Cite this article
Bernd L. Schmitz, Georg Grön, Florian Brausewetter, Martin H.K. Hoffmann, Andrik J. Aschoff
Enhancing Gray-to-White Matter Contrast in 3T T1 Spin-Echo Brain Scans by Optimizing Flip Angle
American Journal of Neuroradiology Sep 2005, 26 (8) 2000-2004;

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Enhancing Gray-to-White Matter Contrast in 3T T1 Spin-Echo Brain Scans by Optimizing Flip Angle
Bernd L. Schmitz, Georg Grön, Florian Brausewetter, Martin H.K. Hoffmann, Andrik J. Aschoff
American Journal of Neuroradiology Sep 2005, 26 (8) 2000-2004;
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