Article Figures & Data
Figures
- Fig 1.
The image data processing is fully automated and consists of the following steps: 1) coregistration of the postimplantation image to the preimplantation image; 2A) normalization of the preimplantation image; 2B) normalization of the postimplantation image based on the transformation parameters derived from the normalization of the preimplantation image; 3A) brain extraction in the preimplantation image; and 3B) brain extraction in the coregistered postimplantation image by using the skull-stripped preimplantation image as a mask.
- Fig 2.
The resulting skull-stripped postimplantation image is visualized within MRIcro. A simultaneous examination of the skull-stripped preimplantation and postimplantation 3D MR images in two yoked MRIcro application windows gives an excellent overview of the exact location of each electrode contact. The viewer is able to grasp the electrodes’ spatial relation to the sulcal pattern of the brain and to anatomic landmarks (e.g., the central sulcus as pointed out here by the crosshairs).
- Fig 3.
Subdural strip and double strip electrodes and their relationship to the Sylvian fissure (left) and to the precentral gyrus (right).
- Fig 4.
Lesions beneath the grid or the brain surface (here polymicrogyria) can be highlighted by loading as color-coded overlays and subsequent semitransparent volume rendering. The individual position of each electrode contact with respect to the presumed epileptogenic lesion can be exactly depicted by using yoked coregistered planar MR images alongside the 3D MR imaging data.
- Fig 5.
To allow for optimal visualization of electrodes on the posterior basal surface of the brain, the brain extraction (see Fig 1, step 3B) is optionally combined with masking the cerebellum in the skull-stripped postimplantation image.
