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Research ArticleBRAIN

Diffusion Tensor Imaging of the Corticospinal Tract before and after Mass Resection as Correlated with Clinical Motor Findings: Preliminary Data

Bryan J. Laundre, Brian J. Jellison, Behnam Badie, Andrew L. Alexander and Aaron S. Field
American Journal of Neuroradiology April 2005, 26 (4) 791-796;
Bryan J. Laundre
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Brian J. Jellison
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Behnam Badie
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Andrew L. Alexander
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Aaron S. Field
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    Fig 1.

    Patient 1. Preoperative (A–C) and postoperative (D–F) axial images of a right thalamic pilocytic astrocytoma: contrast-enhanced T1-weighted images (A and D), T2-weighted images (B and E), and directional color maps (C and F). Before surgery, DTI reveals decreased FA (diminished blue in C) and posteromedial displacement of the right PLIC (arrow in C). After surgery, DTI shows persistently decreased FA and displacement of the right PLIC (arrowhead in F).

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    Fig 2.

    Patient 2. Preoperative (A–C) and postoperative (D–F) axial images of a left frontal pilocytic astrocytoma: contrast-enhanced T1-weighted images (A and D), T2-weighted images (B and E), and directional color maps (C and F). Before surgery, DTI reveals decreased FA (diminished blue in C) and posteromedial displacement of the left PLIC (arrow in C). After surgery, DTI shows both restored FA (normal blue in F) and normal positioning of the left PLIC.

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    Fig 3.

    Patient 3. Preoperative (A–C) and postoperative (D–F) axial images of a left thalamic ganglioglioma: contrast-enhanced T1-weighted images (A and D), T2-weighted images (B and E), and directional color maps (C and F). Before surgery, DTI reveals lateral displacement of the left PLIC (arrow in C); after surgery, DTI shows that the position has returned to normal.

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    Fig 4.

    Patient 4. Preoperative (A–C) and postoperative (D–F) axial images of the right striatal hemorrhagic cavernous angioma: contrast-enhanced T1-weighted images (A and D), T2-weighted images (B and E), and directional color maps (C and F). Before surgery, DTI reveals only slight displacement of the right PLIC. After surgery, DTI shows a preserved right PLIC.

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    Fig 5.

    Patient 1. Axial images of the brainstem. Before (A) and after (C) surgery, conventional T2-weighted images show subtle blunting of the right ventral surface of the pons (arrow). Preoperative (B) and postoperative (D) DTI reveals marked diminution of the CST in the right ventral pons, consistent with wallerian degeneration (arrowhead).

Tables

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  • Clinical motor findings and DTI-determined CST involvement

    Patient/Age (y)/SexPathologyLocationMotor DeficitsCST Involvement on DTI
    PreoperativePostoperativePreoperativePostoperative
    1/29/MPilocytic astrocytomaR thalamus2–4/5 L upper extremity2–5/5 L upper extremityDecreased FA, deviated R PLICDecreased FA, deviated R PLIC
    2/20/FPilocytic astrocytomaL frontal4/5 R upper/lower extremityNo deficitDecreased FA, deviated L PLICNormalized L PLIC
    3/46/FGangliogliomaL thalamus3–4/5 R upper/lower extremityNo deficitDeviated L PLICNormalized L PLIC
    4/23/FCavernous angiomaR striatumNo deficitNo deficitUninvolved R PLICPreserved R PLIC
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American Journal of Neuroradiology: 26 (4)
American Journal of Neuroradiology
Vol. 26, Issue 4
1 Apr 2005
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Cite this article
Bryan J. Laundre, Brian J. Jellison, Behnam Badie, Andrew L. Alexander, Aaron S. Field
Diffusion Tensor Imaging of the Corticospinal Tract before and after Mass Resection as Correlated with Clinical Motor Findings: Preliminary Data
American Journal of Neuroradiology Apr 2005, 26 (4) 791-796;

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Diffusion Tensor Imaging of the Corticospinal Tract before and after Mass Resection as Correlated with Clinical Motor Findings: Preliminary Data
Bryan J. Laundre, Brian J. Jellison, Behnam Badie, Andrew L. Alexander, Aaron S. Field
American Journal of Neuroradiology Apr 2005, 26 (4) 791-796;
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