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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNeurointervention

Periprocedural Morbidity and Mortality Associated with Endovascular Treatment of Intracranial Aneurysms

Hae-Kwan Park, Michael Horowitz, Charles Jungreis, Julie Genevro, Christopher Koebbe, Elad Levy and Amin Kassam
American Journal of Neuroradiology March 2005, 26 (3) 506-514;
Hae-Kwan Park
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Michael Horowitz
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Charles Jungreis
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Julie Genevro
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Christopher Koebbe
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Elad Levy
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Amin Kassam
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Article Figures & Data

Tables

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    TABLE 1:

    Locations of aneurysms

    LocationRuptured (n = 118)Unruptured (n = 72)
    Anterior circulation88 (74.6)53 (73.6)
        Anterior choroidal artery42
        Posterior communicating artery34
        Paraclinoid ICA732
        ICA bifurcation52
        A1 segment of the ACA11
        Anterior communicating artery456
        Distal ACA61
        M1 segment of the MCA10
        MCA bifurcation65
    Posterior circulation30 (25.4)19 (26.4)
        Basal artery tip1611
        Distal posterior cerebral artery31
        Superior cerebellar artery23
        Basal artery trunk11
        Vertebrobasilar junction10
        Posterior inferior cerebellar artery73
    • Note.—Data in parentheses are percentages. ACA is anterior cerebral artery; ICA, internal carotid artery; and MCA, middle cerebral artery.

    • View popup
    TABLE 2:

    Procedure-related complications

    ComplicationRuptured (n = 118)Unruptured (n = 72)Retreated (n = 20)Incidence (%)
    Thromboembolism (n = 22)135410.4
    Intraprocedural rupture (n = 9)9004.2
    Coil migration (n = 2)2001.0
    Parent-vessel injury (n = 2)2001.0
    Postprocedural rupture (n = 1)1000.5
    Cranial nerve palsy (n = 1)0100.5
    Total (n = 37)276417.6
    • View popup
    TABLE 3:

    Procedural complications in 118 ruptured aneurysms

    ComplicationNeurologic SequlaeTotalIncidence (%)
    NoneTransientPersistentFatal
    Intraprocedural rupture600397.6
    Postprocedural rupture000110.8
    Thromboembolism11741311.0
    Coil migration100121.7
    Parent-vessel injury200021.7
    Total101792722.9
    • View popup
    TABLE 4:

    Published complication rates for coil embolization of cerebral aneurysms

    ReferenceRate
    Johnston et al6210% procedure-related adverse outcome rate in coiled unruptured aneurysms (adverse outcome not defined)
    Duke et al632.5% procedure-related neurologic deficit rate
    Johnston et al6411% procedure-related adverse outcome rate
    Vanninen et al654% technique-related mortality rate
    Bavinzski et al662.2% procedure-related mortality, 4.4% procedure-related morbidity
    Solander et al2113% procedure-related temporary neurologic complication rate
    Klein et al6724% inadvertent vessel occlusion secondary to coiling, 10% stroke/TIA rate secondary to coiling procedure
    Eskridge et al6823% procedure-related embolus rate
    Guglielmi et al694.8% procedure-related morbidity, 2.4% procedure-related mortality
    Murayama et al704.3% procedure-related neurologic morbidity for unruptured aneurysms
    Kuether et al29.1% procedure-related morbidity, 7.8% procedure-related mortality
    Raymond et al7122% procedure-related neurologic complications, 3% procedure-related mortality
    McDougall et al7210% procedure-related neurologic complications
    Byrne et al7318% procedure-related neurologic complications, 4% procedure-related mortality
    Casasco et al744.2% procedure-related strokes, 7% procedure-related deaths
    Brilstra et al14% procedure-related permanent neurologic complications, 8.5% procedure-related temporary neurologic ischemic complications, 1.1% procedure-related mortality
    Soeda et al7520% procedure-related ischemic event rate in coiling or unruptured aneurysms
    Vinuela et al68.9% procedure-related morbidity, 1.8% procedure-related mortality
    Klotzsch et al7620% procedure-related neurologic complications
    Holley et al777.1% procedure-related neurologic morbidity
    Graves et al788% procedure-related stroke rate
    Pelz et al2228% procedure-related neurologic thromboembolic rate (12% TIA rate, 17% stroke rate)
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American Journal of Neuroradiology: 26 (3)
American Journal of Neuroradiology
Vol. 26, Issue 3
1 Mar 2005
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Cite this article
Hae-Kwan Park, Michael Horowitz, Charles Jungreis, Julie Genevro, Christopher Koebbe, Elad Levy, Amin Kassam
Periprocedural Morbidity and Mortality Associated with Endovascular Treatment of Intracranial Aneurysms
American Journal of Neuroradiology Mar 2005, 26 (3) 506-514;

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Periprocedural Morbidity and Mortality Associated with Endovascular Treatment of Intracranial Aneurysms
Hae-Kwan Park, Michael Horowitz, Charles Jungreis, Julie Genevro, Christopher Koebbe, Elad Levy, Amin Kassam
American Journal of Neuroradiology Mar 2005, 26 (3) 506-514;
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  • Intra-arterial versus intravenous abciximab therapy for thromboembolic complications of neuroendovascular procedures: case review and meta-analysis
  • Safety and efficacy of a new prophylactic tirofiban protocol without oral intraoperative antiplatelet therapy for endovascular treatment of ruptured intracranial aneurysms
  • Next day discharge after elective intracranial aneurysm coiling: is it safe?
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  • Analysis of Complications and Recurrences of Aneurysm Coiling with Special Emphasis on the Stent-Assisted Technique
  • Balloon-assisted coil embolization of intracranial aneurysms is not associated with increased periprocedural complications
  • Results of Screening for Intracranial Aneurysms in Patients with Coarctation of the Aorta
  • Endovascular Treatment of Ruptured Paraclinoid Aneurysms: Results, Complications, and Follow-Up
  • Repair of intracranial vessel perforation with Onyx-18 using an exovascular retreating catheter technique
  • Stent-Supported Aneurysm Coiling: A Literature Survey of Treatment and Follow-Up
  • Preinterventional Clopidogrel Response Variability for Coil Embolization of Intracranial Aneurysms: Clinical Implications
  • Safety of intravenous heparin administration after endovascular treatment for ruptured intracranial aneurysms
  • Angiographic and Clinical Outcomes in 200 Consecutive Patients with Cerebral Aneurysm Treated with Hydrogel-Coated Coils
  • Clinical and Angiographic Follow-up of Ruptured Intracranial Aneurysms Treated with Endovascular Embolization
  • Immediate Clinical Outcome of Patients Harboring Unruptured Intracranial Aneurysms Treated by Endovascular Approach: Results of the ATENA Study
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