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Research ArticleNeurointervention

Preliminary Results of Endovascular Stent-Assisted Angioplasty for Symptomatic Middle Cerebral Artery Stenosis

Tae Hong Lee, Dong Hyun Kim, Byung-Hee Lee, Hak Jin Kim, Chang Hwa Choi, Kyung Pil Park, Dae Soo Jung, Suk Kim and Tae Yong Moon
American Journal of Neuroradiology January 2005, 26 (1) 166-174;
Tae Hong Lee
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Dong Hyun Kim
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Byung-Hee Lee
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Hak Jin Kim
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Chang Hwa Choi
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Kyung Pil Park
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Dae Soo Jung
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Suk Kim
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Tae Yong Moon
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    Fig 1.

    A 71-year-old woman with recurrent TIA symptoms.

    A, Anteroposterior oblique left ICA angiogram shows severe stenosis (about 70%, arrow) in the M1 portion of the left MCA.

    B, Balloon-mounted coronary stent (arrow) is positioned at the lesion, and the microwire is anchored in the distal branch of the MCA.

    C, At 4 atm, the balloon is initially expanded at the distal and proximal ends of the stent (dumbbell phenomenon, arrows).

    D, At 6 atm, the balloon expands in the center section containing the stent (arrow).

    E, When no gap is present between the distal end of the stent and the parent artery on angiography, the balloon tip (long arrow) is pulled back into the distal end of the stent (short arrow) to prevent dissection and rupture of the parent artery. Balloon inflation is restarted.

    F, Immediate postprocedural anteroposterior left ICA angiogram shows excellent recanalization (arrow) of the diseased segment, with preservation of the lateral lenticulostriate arteries.

  • Fig 2.
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    Fig 2.

    A 67-year-old man with recurrent TIA symptoms.

    A, Anteroposterior left ICA angiogram shows severe stenosis (about 90%, arrow) in the proximal M1 portion of the left MCA.

    B, Balloon-mounted coronary stent (arrow) is successfully deployed.

    C, Postprocedural ICA angiogram shows acute in-stent thrombosis (arrow).

    D, Final ICA angiogram after thrombolysis with abciximab shows the MCA (arrow) with a smooth appearance, normalized luminal diameter, and preservation of the lenticulostriate arteries.

    E, Angiogram at 10 months after the procedure shows asymptomatic, mild (20%) in-stent restenosis (arrow) due to intimal hyperplasia.

  • Fig 3.
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    Fig 3.

    A 58-year-old woman with recurrent TIA and infarction symptoms involving the left MCA territories.

    A, Anteroposterior left ICA angiogram shows diffuse severe stenosis (about 90%, arrow) in the total M1 portion of the right MCA.

    B, Anteroposterior radiograph shows the stent (arrow) during deployment in the M1 portion.

    C and D, After stent deployment, left ICA angiogram shows extravasation of contrast agent in the stent (arrow) due to a vascular tear.

    E, Second stent (arrow) is inserted over the tear site.

    F, Postprocedural anteroposterior left ICA angiogram shows the near-normal diameter of the vessel, with no extravasation of contrast agent (arrow).

Tables

  • Figures
  • Patient characteristics, stents used, complications, and outcomes of stenting for symptomatic MCA stenosis

    Patient/Sex/Age (y)Clinical PresentationStent (mm)*ComplicationComplication ManagementStenosis Degree (%)Neurologic OutcomeFollow-Up
    InitialPoststentingDSAIschemic
    1/M/48TIAG 2.5 × 9NoneNA65NAFailNANA
    2/M/51TIAG 3.0 × 9RuptureNA75NADeathNANA
    3/M/71TIAS 2.5 × 9NoneNA700ExcellentNANone, 25 mo
    4/M/67TIAS 2.5 × 15ATAbciximab 8 mg IA805Excellent6 mo, no RSNone, 17 mo
    5/F/74TIAS 2.5 × 15NoneNA700ExcellentNANone, 17 mo
    6/F/58TIA, infarctS 2.5 × 18, S 2.5 × 12Rupture, ATSecond stent overlap, abciximab 10 mg IA900Good10 mo RSNone, 15 mo
    7/M/66TIA, infarctF 2.5 × 9NoneNA600ExcellentNANone, 11 mo
    8/M/60InfarctF 2.5 × 9NoneNA650ExcellentNANone, 11 mo
    9/F/52InfarctF 2.5 × 9NoneNA700Good6 mo, no RSNone, 9 mo
    10/F/49TIA, infarctF 2.5 × 9, F 2.5 × 12Stent jumping, AT, minor strokeSecond stent overlap, abciximab 10 mg IA, IV heparin500Fair3 mo, no RSNone, 9 mo
    11/M/60TIAF 2.75 × 12AT, SATAbciximab 10 mg IA, IA thrombolysis700Fair3 mo, no RSNone, 9 mo
    12/M/67TIAF 2.5 × 9ATAbciximab 10 mg IA600Good6 mo, no RSNone, 8 mo
    13/M/60TIAS 2.5 × 9ATAbciximab 16 mg 1A700ExcellentNANone, 7 mo
    14/M/63InfarctS 2.5 × 9ATAbciximab 16 mg IA650ExcellentNANone, 4 mo
    15/M/41InfarctS 2.5 × 12NoneNA600ExcellentNANone, 3 mo
    16/F/71TIAS 2.5 × 15ATAbciximab 10 mg IA600ExcellentNANone, 2 mo
    17/M/53InfarctS 2.5 × 12ATAbciximab 10 mg IA700ExcellentNANone, 1 mo
    • Note.—Abbreviations: AT, acute in-stent thrombosis; F, Flexmaster (JoMed); G, Gfx (AVE; Medtronic); IA, intra-arterial; IV, intravenous; NA, not applicable; RS, in-stent restenosis; S, S660 (AVE; Medtronic); and SAT, subacute in-stent thrombosis.

    • * Stent implantation was successful in all patients except patient 1.

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American Journal of Neuroradiology: 26 (1)
American Journal of Neuroradiology
Vol. 26, Issue 1
1 Jan 2005
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Tae Hong Lee, Dong Hyun Kim, Byung-Hee Lee, Hak Jin Kim, Chang Hwa Choi, Kyung Pil Park, Dae Soo Jung, Suk Kim, Tae Yong Moon
Preliminary Results of Endovascular Stent-Assisted Angioplasty for Symptomatic Middle Cerebral Artery Stenosis
American Journal of Neuroradiology Jan 2005, 26 (1) 166-174;

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Preliminary Results of Endovascular Stent-Assisted Angioplasty for Symptomatic Middle Cerebral Artery Stenosis
Tae Hong Lee, Dong Hyun Kim, Byung-Hee Lee, Hak Jin Kim, Chang Hwa Choi, Kyung Pil Park, Dae Soo Jung, Suk Kim, Tae Yong Moon
American Journal of Neuroradiology Jan 2005, 26 (1) 166-174;
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  • Intra-arterial versus intravenous abciximab therapy for thromboembolic complications of neuroendovascular procedures: case review and meta-analysis
  • Symptom Differences and Pretreatment Asymptomatic Interval Affect Outcomes of Stenting for Intracranial Atherosclerotic Disease
  • Randomized Controlled Trial of Symptomatic Middle Cerebral Artery Stenosis: Endovascular Versus Medical Therapy in a Chinese population
  • Standard of practice: endovascular treatment of intracranial atherosclerosis
  • Wingspan Stents for the Treatment of Symptomatic Atherosclerotic Stenosis in Small Intracranial Vessels: Safety and Efficacy Evaluation
  • Reporting standards for angioplasty and stent-assisted angioplasty for intracranial atherosclerosis
  • Reporting Standards for Angioplasty and Stent-Assisted Angioplasty for Intracranial Atherosclerosis
  • A Systematic Review on Outcome After Stenting for Intracranial Atherosclerosis
  • Subacute Stent Thrombosis in Intracranial Stenting
  • US Multicenter Experience With the Wingspan Stent System for the Treatment of Intracranial Atheromatous Disease: Periprocedural Results
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