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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleBRAIN

Age-Related, Regional, Hemispheric, and Medial-Lateral Differences in Myelin Integrity in Vivo in the Normal Adult Brain

Carol L. Armstrong, Elfrides Traipe, Jill V. Hunter, John C. Haselgrove, George E. Ledakis, Emily M. Tallent, David Shera and Mark A. van Buchem
American Journal of Neuroradiology June 2004, 25 (6) 977-984;
Carol L. Armstrong
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Elfrides Traipe
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Jill V. Hunter
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John C. Haselgrove
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George E. Ledakis
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Emily M. Tallent
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David Shera
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Mark A. van Buchem
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    TABLE 1:

    Mean magnetization transfer ratios and analysis of variance for substructures of cortical and subcortical regions

    RegionMeanSESignificance (F)
    Mesial temporal37.350.10P = .0005
    Lateral temporal38.210.10
    Prefrontal39.630.16P = .0005
    Medial frontal38.360.16
    Mesial parietal38.970.14P = .61
    Lateral parietal38.870.14
    Genu40.980.22P = .0005
    Body39.520.22
    Splenium39.620.22
    Anterior cingulate39.460.26P = .11
    Posterior cingulate40.090.27
    Lentiform nucleus35.110.13P = .0005
    Head of caudate35.220.13
    Thalamus38.070.13
    Internal capsule39.800.13
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    TABLE 2:

    Hemispheric differences in magnetization transfer ratio of regions as measured by paired t tests

    RegionLeft MeanSDRight MeanSDPaired tPSignificance*
    Hemisphere mean37.551.2537.251.315.41.0005*
    Cortical regions38.771.4438.451.525.57.0005*
    Cingulate39.792.0439.921.791.08.287
    Subcortical36.651.2936.521.252.30.030
    Brain stem37.641.4237.611.340.44.666
    Cerebellum31.851.6132.011.761.25.222
    Frontal39.061.5038.811.543.42.002*
     Prefrontal39.901.6040.051.671.35.188
     Posterior frontal38.861.5938.541.634.52.0005*
    Parietal38.971.9638.762.232.32.029
     Lateral parietal38.982.0038.762.292.25.033
     Mesial parietal39.031.9938.902.141.29.207
    Occipital38.691.6138.651.750.34.733
    Temporal38.351.4137.771.557.52.0005*
     Lateral temporal38.541.4237.871.598.24.0005*
     Mesial temporal37.481.7437.251.631.14.267
    Internal Capsule39.951.5039.671.581.94.063
    Thalamus38.021.3338.111.301.40.174
    Head of the caudate35.321.3035.111.331.25.221
    Lentiform nucleus35.211.4335.011.272.86.008
    • * Significance indicates those results that reach an accepted α of P < .0036 after applying a Bonferroni correction.

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American Journal of Neuroradiology: 25 (6)
American Journal of Neuroradiology
Vol. 25, Issue 6
1 Jun 2004
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Carol L. Armstrong, Elfrides Traipe, Jill V. Hunter, John C. Haselgrove, George E. Ledakis, Emily M. Tallent, David Shera, Mark A. van Buchem
Age-Related, Regional, Hemispheric, and Medial-Lateral Differences in Myelin Integrity in Vivo in the Normal Adult Brain
American Journal of Neuroradiology Jun 2004, 25 (6) 977-984;

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Age-Related, Regional, Hemispheric, and Medial-Lateral Differences in Myelin Integrity in Vivo in the Normal Adult Brain
Carol L. Armstrong, Elfrides Traipe, Jill V. Hunter, John C. Haselgrove, George E. Ledakis, Emily M. Tallent, David Shera, Mark A. van Buchem
American Journal of Neuroradiology Jun 2004, 25 (6) 977-984;
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