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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleSpine Imaging and Spine Image-Guided Interventions

Ionic versus Nonionic Paramagnetic Contrast Media in Differentiating between Postoperative Scar and Recurrent Disk

Jui-Sheng Hsu, Gin-Chung Liu, Shih-Hsien Chen, Twei-Shiun Jaw, Wun-Jer Shen and Chiao-Yun Chen
American Journal of Neuroradiology June 2004, 25 (6) 1110-1115;
Jui-Sheng Hsu
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Gin-Chung Liu
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Shih-Hsien Chen
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Twei-Shiun Jaw
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Wun-Jer Shen
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Chiao-Yun Chen
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  • Fig 1.
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    Fig 1.

    Axial view images of a patient with surgically confirmed recurrent herniated disk.

    A, Obtained before the administration of gadopentetate dimeglumine (0.1 mmol/kg).

    B, Obtained 5 min after the administration of gadopentetate dimeglumine (0.1 mmol/kg).

    C, Obtained 50 min after the administration of gadopentetate dimeglumine (0.1 mmol/kg).

    D, Obtained 5 min after the administration of contrast medium. Placement of cursor to measure recurrent disk (1) and scar (2) enhancement. Contrast ratio between scar and recurrent disk fragment is greater at 5 min than at 50 min.

  • Fig 2.
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    Fig 2.

    Graph of the average enhancement in scar and in recurrent disk fragment as a function of time after the injection of 0.1 mmol/kg gadopentetate dimeglumine (M) or gadodiamide (O). The scar tended to decrease in enhancement and the recurrent disk fragment tended to increase in enhancement with time.

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    Fig 3.

    MR images of a patient with recurrent herniated disk

    A, Sagittal view unenhanced T2-weighted MR image.

    B, Axial view image obtained before the IV administration of ionic contrast medium.

    C, Axial view image obtained 5 min after the IV administration of ionic contrast medium.

    D, Axial view image obtained 50 min after the IV administration of ionic contrast medium. Contrast ratio is greater after administration of ionic rather than nonionic contrast media at 50 min (see panel G).

    E, Axial view image obtained before the IV administration of nonionic contrast medium.

    F, Axial view image obtained 5 min after the IV administration of nonionic contrast medium.

    G, Axial view image obtained 50 min after the IV administration of nonionic contrast medium. Contrast ratio is greater after administration of ionic rather than nonionic contrast media at 50 min.

  • Fig 4.
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    Fig 4.

    Graph of the contrast ratio between scar and recurrent disk fragment as a function of time after injection of 0.1 mmol/kg ionic (M) and nonionic (O) contrast medium. The contrast radio tended to decrease with time (arithmetic mean ± SD, n = 20).

Tables

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    TABLE 1:

    Contrast enhancement in recurrent disk fragment and scar after IV injection of ionic and nonionic contrast media

    LocationType of Contrast MediumEnhancement at Time after Injection (min)
    5254050
    Ionic0.60 ± 0.100.68 ± 0.070.72 ± 0.070.70 ± 0.07
    DiskNonionic0.58 ± 0.090.66 ± 0.080.71 ± 0.080.70 ± 0.08
    Ionic1.37 ± 0.261.15 ± 0.180.98 ± 0.170.90 ± 0.15
    ScarNonionic1.04 ± 0.210.88 ± 0.150.83 ± 0.120.78 ± 0.11
    • * Enhancement is expressed as arithmetic mean ± SD (n = 20).

    • View popup
    TABLE 2:

    Contrast between the scar and recurrent disk fragment after IV injection of ionic and nonionic contrast media

    Type of Contrast MediumContrast (SI scar/SI disk) at Time after Injection (min)
    05254050
    Ionic1.32 ± 0.421.95 ± 0.801.66 ± 0.671.40 ± 0.421.32 ± 0.41
    Nonionic1.37 ± 0.611.93 ± 0.781.54 ± 0.441.30 ± 0.441.20 ± 0.56
    • Note.—SI indicates signal intensity.

    • * Contrast between scar and recurrent disc fragment is expressed as arithmetic mean ± SD (n = 20).

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American Journal of Neuroradiology: 25 (6)
American Journal of Neuroradiology
Vol. 25, Issue 6
1 Jun 2004
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Ionic versus Nonionic Paramagnetic Contrast Media in Differentiating between Postoperative Scar and Recurrent Disk
Jui-Sheng Hsu, Gin-Chung Liu, Shih-Hsien Chen, Twei-Shiun Jaw, Wun-Jer Shen, Chiao-Yun Chen
American Journal of Neuroradiology Jun 2004, 25 (6) 1110-1115;
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Show more SPINE IMAGING AND SPINE IMAGE-GUIDED INTERVENTIONS

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Jui-Sheng Hsu, Gin-Chung Liu, Shih-Hsien Chen, Twei-Shiun Jaw, Wun-Jer Shen, Chiao-Yun Chen
Ionic versus Nonionic Paramagnetic Contrast Media in Differentiating between Postoperative Scar and Recurrent Disk
American Journal of Neuroradiology Jun 2004, 25 (6) 1110-1115;

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