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Improved Turnaround Times | Median time to first decision: 12 days

Research ArticleNeurointervention

Anatomically Conformable, Three-Dimensional, Detachable Platinum Microcoil System for the Treatment of Intracranial Aneurysms

David Niemann, Richard Aviv, Caroline Cowsill, Mary Sneade and Andrew J. Molyneux
American Journal of Neuroradiology May 2004, 25 (5) 813-818;
David Niemann
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Richard Aviv
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Caroline Cowsill
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Mary Sneade
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Andrew J. Molyneux
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Article Figures & Data

Figures

  • Tables
  • Fig 1.
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    Fig 1.

    Patient 1.

    A, Small, wide-necked, ruptured aneurysm of the anterior cerebral artery.

    B, After treatment with a single, spherical ACT coil.

  • Fig 2.
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    Fig 2.

    Patient 2.

    A, Ruptured aneurysm of the middle cerebral artery bifurcation with a spherical dome and proximal tubular segment.

    B, After treatment with a 6-mm, spherical ACT coil and four small helical coils.

  • Fig 3.
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    Fig 3.

    Patient 3.

    A, Wide-necked, ruptured aneurysm of the posterior communicating artery.

    B, After treatment with a 5-mm, spherical ACT coil as a basket followed by several small helical coils.

Tables

  • Figures
    • View popup
    TABLE 1:

    Clinical presentations and grades

    PresentationNo. of Patients (n = 133)
    SAH110
     WFNS grade 1*61
     WFNS grade 2*13
     WFNS grade 3*7
     WFNS grade 4*7
     WFNS grade 5*22
    Incidental15
    Mass3†
    Headache2
    Ischemic stroke1
    Seizure2
    • * At the time of treatment.

    • † Cranial nerves II and III.

    • View popup
    TABLE 2:

    Questionnaire used to assess modified Rankin scale scores

    ScoreFunctional OutcomeQuestionnaire Response
    0No symptoms“I have no symptoms and I cope well with life.”
    1Minor symptoms“I have a few symptoms but these do not interfere with my everyday life.”
    2Some restriction in lifestyle“I have symptoms, which have changed my life but I am still able to look after myself.”
    3Significant restriction in lifestyle“I have symptoms, which have significantly changed my life and prevent me from coping fully, and I need some help looking after myself.”
    4Partly dependent“I have quite severe symptoms, which means I need to have help from other people but I am not so bad as to need attention day and night.”
    5Fully dependent“I have major symptoms, which severely handicap me and I need constant attention day and night.”
    6DeadNot applicable.
    • View popup
    TABLE 3:

    Aneurysm angiographic outcomes

    Occlusion GradeNo. of Aneurysms
    At treatment (n = 141)
     I104 (74%)
     II34 (24%)
     III3 (2%)
    At follow-up (n = 94)
     I74 (79%)
     II17 (18%)
     III3 (3%)
    • Note—Average radiographic follow-up was 10 months. Occlusion grades were as follows: I, complete angiographic occlusion, no neck remnant, approximately 100%; II, subtotal occlusion, coils at the neck but some body filling or small neck remnant, approximately 95–99%; and III, incomplete occlusion, residual aneurysm body filling or sizable neck remnant or coil compaction, <95%.

    • View popup
    TABLE 4:

    Aneurysm location and size

    No. of Aneurysms (n = 141)
    Arterial location
     Internal carotid47
     Anterior cerebral30
     Anterior communicating15
     Middle cerebral33
     Posterior cerebral1
     Superior cerebellar1
     Basilar termination9
     Anterior inferior cerebral2
     Vertebral3
    Size
     <10 mm with neck <4 mm75
     <10 mm with neck ≥4 mm40
     ≥10 mm with neck <4 mm8
     ≥10 mm with neck ≥4 mm18
    • View popup
    TABLE 5:

    Clinical outcomes

    Modified Rankin ScoreNo. of Patients
    SAH, WFNS grades 1–3 pretreatment (n = 80)
     025
     135
     210
     36
     41
     50
     63
    SAH, WFNS grades 4–5 pretreatment (n = 30)
     03
     16
     25
     34
     40
     52
     610
    Unruptured aneurysm (n = 23)
     010
     16
     25
     3*1
     40
     51
     60
    • Note—Average clinical follow-up was 15 months.

    • * Patient presented with ischemic stroke.

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American Journal of Neuroradiology: 25 (5)
American Journal of Neuroradiology
Vol. 25, Issue 5
1 May 2004
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Anatomically Conformable, Three-Dimensional, Detachable Platinum Microcoil System for the Treatment of Intracranial Aneurysms
David Niemann, Richard Aviv, Caroline Cowsill, Mary Sneade, Andrew J. Molyneux
American Journal of Neuroradiology May 2004, 25 (5) 813-818;
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Cite this article
David Niemann, Richard Aviv, Caroline Cowsill, Mary Sneade, Andrew J. Molyneux
Anatomically Conformable, Three-Dimensional, Detachable Platinum Microcoil System for the Treatment of Intracranial Aneurysms
American Journal of Neuroradiology May 2004, 25 (5) 813-818;

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