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Degenerative Thalamic Hamartoma: CT and MR Imaging Features

Tomoki Kaneko, Rei Kawakami, Yasunari Fujinaga, Kazuhiro Oguchi, Jun Nakayama, Kazuhiro Hongo and Masumi Kadoya
American Journal of Neuroradiology May 2004, 25 (5) 766-768;
Tomoki Kaneko
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Rei Kawakami
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Yasunari Fujinaga
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Kazuhiro Oguchi
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Jun Nakayama
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Kazuhiro Hongo
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Masumi Kadoya
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    Fig 1.

    Noncontrast CT scan shows a low-attenuation mass in the right thalamus. Marked calcifications are seen in the center of the mass lesion (arrow).

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    Fig 2.

    Axial MR images. All images are obtained at same level.

    A, T1-weighted image (500/20 [TR/TE]). B, T2-weighted image (5000/88 [TR/TE]). C, T1-weighted (500/20 [TR/TE]) image after gadolinium-DTPA administration.

    The mass lesion shows lower signal intensity on the T1-weighted image (A) and higher signal intensity on the T2-weighted MR image (B) relative to gray matter. Calcified regions show slightly greater signal intensity on the T1-weighted image (A) and are enhanced after administration of gadolinium-DTPA (C, light arrows). CSF-like signal intensity exists in the core of the lesion (dark arrows).

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    Fig 3.

    A, Coronal image after administration of gadolinium-DTPA (500/20 [TR/TE]). B, Sagittal T2-weighted image (4000/88.9 [TR/TE]). The margin of the mass lesion is covered with thalamus extending in a beaklike shape (arrows).

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    Fig 4.

    A, Hematoxylin and eosin stain (magnification ×100). B, N-CAM stain (magnification ×200). C, Polysialic acid stain (magnification ×200).

    Proliferation of vessels and minute calcified corpuscles (dark arrows) are observed. There are no atypical cells or abnormal division of nucleus. Immunohistochemical staining is positive for N-CAM (dark arrows) and negative for polysialic acid.

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American Journal of Neuroradiology: 25 (5)
American Journal of Neuroradiology
Vol. 25, Issue 5
1 May 2004
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Tomoki Kaneko, Rei Kawakami, Yasunari Fujinaga, Kazuhiro Oguchi, Jun Nakayama, Kazuhiro Hongo, Masumi Kadoya
Degenerative Thalamic Hamartoma: CT and MR Imaging Features
American Journal of Neuroradiology May 2004, 25 (5) 766-768;

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Degenerative Thalamic Hamartoma: CT and MR Imaging Features
Tomoki Kaneko, Rei Kawakami, Yasunari Fujinaga, Kazuhiro Oguchi, Jun Nakayama, Kazuhiro Hongo, Masumi Kadoya
American Journal of Neuroradiology May 2004, 25 (5) 766-768;
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