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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleBrain

Imaging Features of Calvarial Tuberculosis: A Study of 42 Cases

Abhijit A. Raut, Arpit M. Nagar, Datta Muzumdar, Ashish J. Chawla, Ranjeet S. Narlawar, Sudhir Fattepurkar and Veena L. Bhatgadde
American Journal of Neuroradiology March 2004, 25 (3) 409-414;
Abhijit A. Raut
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Arpit M. Nagar
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Datta Muzumdar
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Ashish J. Chawla
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Ranjeet S. Narlawar
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Sudhir Fattepurkar
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Veena L. Bhatgadde
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Figures

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  • Fig 1.
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    Fig 1.

    Lateral radiograph shows large circumscribed lytic lesion in frontal bone.

  • Fig 2.
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    Fig 2.

    Anteroposterior radiograph demonstrates a large frontoparietal lytic lesion suggestive of diffuse spreading type.

  • Fig 3.
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    Fig 3.

    Frontal radiograph shows a lytic lesion with a sclerotic margin.

  • Fig 4.
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    Fig 4.

    A, Contrast-enhanced axial CT scan shows peripherally enhancing epidural collection in left frontal region with bone defect and scalp swelling. B, Axial CT with a bone window shows left frontal calvarial defect destroying both inner and outer tables. Note the bony sequestration.

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    Fig 5.

    Contrast-enhanced coronal CT scan shows right frontal epidural collection with subgaleal soft tissue. Note the circumscribed area of encephalomalacia of CSF attenuation.

  • Fig 6.
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    Fig 6.

    A, Coronal CT scan demonstrates a peripherally enhancing epidural collection over parietal region, crossing the midline associated with subgaleal soft tissue. On subsequent imaging, superior sagittal sinus showed no evidence of filling defect. The sinus tract is seen. B, Coronal bone window demonstrates destruction of right parietal bone.

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    Fig 7.

    A, Axial T1- weighted MR image shows a predominantly isointense lesion in the right parietal bone. The hypointensity within it is suggestive of sinus tract. A streak of hyperintensity is also seen in the epidural region. B, Axial T2-weighted MR image shows the hypointense lesion in the right parietal bone. The epidural collection is hyperintense. C, Axial T1-weighted contrast-enhanced MR image shows diffuse enhancement of the calvarial lesion.

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    Fig 8.

    Histopathologic analysis (Ziehl Nelsen stain) of surgical specimen obtained from the lesion showing multiple epitheloid granulomas with central caseation and palisade epitheloid cells (white arrowhead) with Langerhans giant cells (white arrow). Magnification ×100.

Tables

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    TABLE 1:

    Demographic distribution of patients

    CharacteristicNumber of Cases (%)
    Age (y):
     0–102 (4.7)
     11–2026 (61.9)
     21–3012 (28.5)
     31–402 (4.7)
     >410 (0)
    Sex:
     Male28 (66)
     Female18 (33)
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    TABLE 2:

    Clinical features of calvarial tuberculosis

    FeatureNumber of Cases (%)
    Scalp swelling39 (92.8)
    Sinuses22 (52.3)
    Seizures4 (.095)
    Meningitis2 (.047)
    Duration of Presenting Symptoms (mo)
    Sinuses:
     0–18 (19)
     2–327 (64)
     4–64 (9)
     >63 (7)
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    TABLE 3:

    Radiologic features of calvarial tuberculosis

    FeatureNumber of Cases (%)
    Location:
     Parietal bone22 (52.3)
     Frontal bone14 (33.3)
     Occipital bone6 (14.2)
    Plain radiographic finding:
     Circumscribed lesions31 (73.8)
     Sclerotic lesions3 (7)
     Diffuse spreading8 (19)
     Subgaleal soft tissue39 (92.8)
    CT scan finding:
     Extradural soft tissue22 (52)
     Calvarial destruction36 (85.7)
     Parenchymal involvement5 (11.9)
     Subgaleal soft tissue38 (90)
     Sinus formation22 (52.3)
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American Journal of Neuroradiology: 25 (3)
American Journal of Neuroradiology
Vol. 25, Issue 3
1 Mar 2004
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Cite this article
Abhijit A. Raut, Arpit M. Nagar, Datta Muzumdar, Ashish J. Chawla, Ranjeet S. Narlawar, Sudhir Fattepurkar, Veena L. Bhatgadde
Imaging Features of Calvarial Tuberculosis: A Study of 42 Cases
American Journal of Neuroradiology Mar 2004, 25 (3) 409-414;

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Imaging Features of Calvarial Tuberculosis: A Study of 42 Cases
Abhijit A. Raut, Arpit M. Nagar, Datta Muzumdar, Ashish J. Chawla, Ranjeet S. Narlawar, Sudhir Fattepurkar, Veena L. Bhatgadde
American Journal of Neuroradiology Mar 2004, 25 (3) 409-414;
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