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Research ArticleBrain

MR Imaging-Related Heating of Deep Brain Stimulation Electrodes: In Vitro Study

Daniel A. Finelli, Ali R. Rezai, Paul M. Ruggieri, Jean A. Tkach, John A. Nyenhuis, Greg Hrdlicka, Ashwini Sharan, Jorge Gonzalez-Martinez, Paul H. Stypulkowski and Frank G. Shellock
American Journal of Neuroradiology November 2002, 23 (10) 1795-1802;
Daniel A. Finelli
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Ali R. Rezai
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Paul M. Ruggieri
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Jean A. Tkach
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John A. Nyenhuis
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Greg Hrdlicka
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Ashwini Sharan
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Jorge Gonzalez-Martinez
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Paul H. Stypulkowski
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Frank G. Shellock
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    Fig 1.

    Phantom and experimental setup. Photograph shows the plexiglass phantom before filling with the gel saline solution shows the plastic grid frame and adjustable posts, which allow precise positioning and support of the dual implantable pulse generators, extensions, and DBS leads. The cables for the four fluoroptic thermometry probes are seen coursing off the bottom of the photograph.

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    Fig 2.

    DBS lead mean temperature elevation as a function of local SAR. Plot shows greatest observed mean temperature elevation for 1 min of data collection, obtained at the time of peak heating during the 10- to 15-minute imaging time interval, versus local SAR value for single and multisection fast spin-echo images. Linear regression (all data points): r = 0.994, P < .001, x variable = 0.88, and y intercept = −0.13.

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    TABLE 1:

    Deep brain stimulation temperature measurements

    SequenceSAR (W/kg)Temperature (°C)ΔTmean (°C)ΔTmax (°C)P < .01
    LocalWhole BodyBaselineImaging
    Standardized sequence
     FSE SS7.130.2424.8 ± 0.130.5 ± 0.15.75.8*
     FSE SS3.870.1324.6 ± 0.228.2 ± 0.13.63.7*
     FSE SS2.100.0724.4 ± 0.126.1 ± 0.11.72.3*
     FSE SS1.120.0424.9 ± 0.125.8 ± 0.20.91.3*
     FSE MS7.260.2424.8 ± 0.131.3 ± 0.16.56.7*
     FSE MS2.170.0724.8 ± 0.126.6 ± 0.11.82.0*
     FSE MS0.500.0224.1 ± 0.124.2 ± 0.10.10.3
    Clinical sequences
     EPI0.140.0023.7 ± 0.123.9 ± 0.10.20.3
     MPRAGE0.360.0123.3 ± 0.123.4 ± 0.10.10.2
     QMT3.440.1123.8 ± 0.124.8 ± 0.11.01.5*
     MT MRA4.280.1424.2 ± 0.125.8 ± 0.11.61.8*
    • Note.—SAR indicates specific absorption rate; ΔTmean, mean temperature increase; ΔTmax, maximum observed temperature increase; FSE, fast spin-echo; SS, single section; MS, multisection; EPI, echo-planar imaging; MPRAGE, magnetization prepared rapid acquisition gradient-echo; QMT, quantitative magnetization transfer; MT MRA, magnetization transfer-suppressed MR angiography. Baseline temperature is the mean ± 1 SD of 12 consecutive measurements (1 min of data) at ambient conditions before the start of the MR imaging sequence. Imaging temperature is the mean ± 1 SD of 12 consecutive measurements (1 min of data) obtained during 10 to 15 min of continuous imaging, encompassing the time of the maximum observed temperature increase. For all measurements, the background reference temperature increase was <0.5°C.

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American Journal of Neuroradiology: 23 (10)
American Journal of Neuroradiology
Vol. 23, Issue 10
1 Nov 2002
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Cite this article
Daniel A. Finelli, Ali R. Rezai, Paul M. Ruggieri, Jean A. Tkach, John A. Nyenhuis, Greg Hrdlicka, Ashwini Sharan, Jorge Gonzalez-Martinez, Paul H. Stypulkowski, Frank G. Shellock
MR Imaging-Related Heating of Deep Brain Stimulation Electrodes: In Vitro Study
American Journal of Neuroradiology Nov 2002, 23 (10) 1795-1802;

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MR Imaging-Related Heating of Deep Brain Stimulation Electrodes: In Vitro Study
Daniel A. Finelli, Ali R. Rezai, Paul M. Ruggieri, Jean A. Tkach, John A. Nyenhuis, Greg Hrdlicka, Ashwini Sharan, Jorge Gonzalez-Martinez, Paul H. Stypulkowski, Frank G. Shellock
American Journal of Neuroradiology Nov 2002, 23 (10) 1795-1802;
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