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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatric Neuroimaging

Terminal Zones of Myelination: MR Evaluation of Children Aged 20–40 Months

Cecilia Parazzini, Cristina Baldoli, Giuseppe Scotti and Fabio Triulzi
American Journal of Neuroradiology November 2002, 23 (10) 1669-1673;
Cecilia Parazzini
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Cristina Baldoli
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Giuseppe Scotti
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Fabio Triulzi
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  • Fig 1.
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    Fig 1.

    Axial T2-weighted MR images.

    A, Image in a 21-month-old girl with grade 0 myelination in the frontal lobe. The subcortical white matter is clearly hyperintense, so not myelinated, in the prerolandic area and along the first and second convolutions bilaterally. Subcortical hyperintensity was also evident in the frontopolar regions.

    B, Example of grade 2 myelination in the frontal area. A T2 hyperintensity is present along the first and second convolutions, while the prerolandic area is myelinated.

    C, Example of grade 3 myelination. T2 hyperintensity is no longer evident, and myelination appears complete.

  • Fig 2.
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    Fig 2.

    Histogram of frontal lobe myelination. Numbers on x axis are ages in months.

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    Fig 3.

    Histogram of temporal lobe myelination. Numbers on x axis are ages in months.

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    Fig 4.

    Histogram of parietal lobe myelination. Numbers on x axis are ages in months.

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    Fig 5.

    Histogram of peritrigonal area myelination. Numbers on x axis are ages in months.

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    Fig 6.

    A and B, Axial T2-weighted MR images show grade 0 myelination in the temporal lobe. Subcortical T2 hyperintensity is recognizable in both temporopolar (A) and temporolateral (B) areas.

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    Fig 7.

    Axial T2-weighted MR image shows peritrigonal linear areas of hyperintensity that can be referred to perivascular spaces.

Tables

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  • Subdivision of marker sites and summary of grading system

    GradeMarker Sites
    Frontal LobeTemporal LobeParietal LobePeritrigonal Area
    Pre-RPolarI–IILateralPolarPost-RGyriPosteriorSuperior
    0−−−−−−−−−
    1+−−+−+−+−
    2++−++++++
    3+++
    • Note.—R indicates rolandic; I–II, first and second convolutions; +, presence of myelination (absence of T2 hyperintensity); −, absence of myelination (presence of T2 hyperintensity).

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American Journal of Neuroradiology: 23 (10)
American Journal of Neuroradiology
Vol. 23, Issue 10
1 Nov 2002
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Cite this article
Cecilia Parazzini, Cristina Baldoli, Giuseppe Scotti, Fabio Triulzi
Terminal Zones of Myelination: MR Evaluation of Children Aged 20–40 Months
American Journal of Neuroradiology Nov 2002, 23 (10) 1669-1673;

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Terminal Zones of Myelination: MR Evaluation of Children Aged 20–40 Months
Cecilia Parazzini, Cristina Baldoli, Giuseppe Scotti, Fabio Triulzi
American Journal of Neuroradiology Nov 2002, 23 (10) 1669-1673;
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